Tissue Fixation

"Tissue Fixation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The technique of using FIXATIVES in the preparation of cytologic, histologic, or pathologic specimens for the purpose of maintaining the existing form and structure of all the constituent elements.

Descriptor ID	D016707
MeSH Number(s)	E01.370.225.500.620.760.720 E01.370.225.750.600.760.720 E05.200.500.620.760.720 E05.200.750.600.760.720
Concept/Terms	Tissue Fixation Tissue Fixation Fixation, Tissue

Below are MeSH descriptors whose meaning is more general than "Tissue Fixation".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Diagnosis [E01]
Diagnostic Techniques and Procedures [E01.370]
Clinical Laboratory Techniques [E01.370.225]
Cytological Techniques [E01.370.225.500]
Histocytological Preparation Techniques [E01.370.225.500.620]
Tissue Preservation [E01.370.225.500.620.760]
Tissue Fixation [E01.370.225.500.620.760.720]
Histological Techniques [E01.370.225.750]
Histocytological Preparation Techniques [E01.370.225.750.600]
Tissue Preservation [E01.370.225.750.600.760]
Tissue Fixation [E01.370.225.750.600.760.720]
Investigative Techniques [E05]
Clinical Laboratory Techniques [E05.200]
Cytological Techniques [E05.200.500]
Histocytological Preparation Techniques [E05.200.500.620]
Tissue Preservation [E05.200.500.620.760]
Tissue Fixation [E05.200.500.620.760.720]
Histological Techniques [E05.200.750]
Histocytological Preparation Techniques [E05.200.750.600]
Tissue Preservation [E05.200.750.600.760]
Tissue Fixation [E05.200.750.600.760.720]

Below are MeSH descriptors whose meaning is related to "Tissue Fixation".

Below are MeSH descriptors whose meaning is more specific than "Tissue Fixation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Tissue Fixation" by people in this website by year, and whether "Tissue Fixation" was a major or minor topic of these publications.

Bar chart showing 35 publications over 22 distinct years, with a maximum of 3 publications in 1997 and 2005 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1996	0	2	2
1997	1	2	3
1999	0	1	1
2001	0	2	2
2003	0	1	1
2004	1	0	1
2005	0	3	3
2006	1	1	2
2008	0	1	1
2010	0	1	1
2011	0	2	2
2012	0	1	1
2014	0	1	1
2015	2	0	2
2016	0	1	1
2017	1	1	2
2018	3	0	3
2019	0	2	2
2020	0	1	1
2021	1	0	1
2022	0	1	1

Below are the most recent publications written about "Tissue Fixation" by people in Profiles.

Zhang Y, Blomquist TM, Kusko R, Stetson D, Zhang Z, Yin L, Sebra R, Gong B, Lococo JS, Mittal VK, Novoradovskaya N, Yeo JY, Dominiak N, Hipp J, Raymond A, Qiu F, Arib H, Smith ML, Brock JE, Farkas DH, Craig DJ, Crawford EL, Li D, Morrison T, Tom N, Xiao W, Yang M, Mason CE, Richmond TA, Jones W, Johann DJ, Shi L, Tong W, Willey JC, Xu J. Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples. Genome Biol. 2022 06 29; 23(1):141.

View in: PubMed
West CA, Lu X, Grimsley G, Norris-Caneda K, Mehta AS, Angel PM, Drake RR. Optimization of Multiple Glycosidase and Chemical Stabilization Strategies for N-Glycan Isomer Detection by Mass Spectrometry Imaging in Formalin-Fixed, Paraffin-Embedded Tissues. Methods Mol Biol. 2021; 2271:303-316.

View in: PubMed
Clift CL, Drake RR, Mehta A, Angel PM. Multiplexed imaging mass spectrometry of the extracellular matrix using serial enzyme digests from formalin-fixed paraffin-embedded tissue sections. Anal Bioanal Chem. 2021 Apr; 413(10):2709-2719.

View in: PubMed
Rowsey R, Znoyko I, Wolff DJ. Whole-Genome Single Nucleotide Polymorphism Microarray for Copy Number and Loss of Heterozygosity Analysis in Tumors. Methods Mol Biol. 2019; 1908:89-111.

View in: PubMed
Scott DA, Casadonte R, Cardinali B, Spruill L, Mehta AS, Carli F, Simone N, Kriegsmann M, Del Mastro L, Kriegsmann J, Drake RR. Increases in Tumor N-Glycan Polylactosamines Associated with Advanced HER2-Positive and Triple-Negative Breast Cancer Tissues. Proteomics Clin Appl. 2019 01; 13(1):e1800014.

View in: PubMed
Angel PM, Norris-Caneda K, Drake RR. In Situ Imaging of Tryptic Peptides by MALDI Imaging Mass Spectrometry Using Fresh-Frozen or Formalin-Fixed, Paraffin-Embedded Tissue. Curr Protoc Protein Sci. 2018 11; 94(1):e65.

View in: PubMed
Drake RR, Powers TW, Norris-Caneda K, Mehta AS, Angel PM. In Situ Imaging of N-Glycans by MALDI Imaging Mass Spectrometry of Fresh or Formalin-Fixed Paraffin-Embedded Tissue. Curr Protoc Protein Sci. 2018 11; 94(1):e68.

View in: PubMed
Angel PM, Mehta A, Norris-Caneda K, Drake RR. MALDI Imaging Mass Spectrometry of N-glycans and Tryptic Peptides from the Same Formalin-Fixed, Paraffin-Embedded Tissue Section. Methods Mol Biol. 2018; 1788:225-241.

View in: PubMed
Angel PM, Comte-Walters S, Ball LE, Talbot K, Mehta A, Brockbank KGM, Drake RR. Mapping Extracellular Matrix Proteins in Formalin-Fixed, Paraffin-Embedded Tissues by MALDI Imaging Mass Spectrometry. J Proteome Res. 2018 01 05; 17(1):635-646.

View in: PubMed
Tam H, Zhang W, Infante D, Parchment N, Sacks M, Vyavahare N. Fixation of Bovine Pericardium-Based Tissue Biomaterial with Irreversible Chemistry Improves Biochemical and Biomechanical Properties. J Cardiovasc Transl Res. 2017 Apr; 10(2):194-205.

View in: PubMed

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