Dioctyl Sulfosuccinic Acid
"Dioctyl Sulfosuccinic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
All-purpose surfactant, wetting agent, and solubilizer used in the drug, cosmetics, and food industries. It has also been used in laxatives and as cerumenolytics. It is usually administered as either the calcium, potassium, or sodium salt.
Descriptor ID |
D004143
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MeSH Number(s) |
D02.241.081.337.759.249
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Concept/Terms |
Docusate- Docusate
- Dioctylsulfosuccinate
- DOSS
- Dioctyl Sulfosuccinate
- Sulfosuccinate, Dioctyl
Docusate Sodium- Docusate Sodium
- Dioctyl Sulfosuccinic Acid, Sodium Salt
- Sodium Bis(2-ethylhexyl)sulfosuccinate
- DEH-Na-SS
- DEH Na SS
- Sodium Dioctylsulphosuccinate
- Dioctylsulphosuccinate, Sodium
- Diethylhexyl Sodium Sulfosuccinate
- Sodium Sulfosuccinate, Diethylhexyl
- Sulfosuccinate, Diethylhexyl Sodium
- Sodium Dioctyl Sulfosuccinate
- Dioctyl Sulfosuccinate, Sodium
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Below are MeSH descriptors whose meaning is more general than "Dioctyl Sulfosuccinic Acid".
Below are MeSH descriptors whose meaning is more specific than "Dioctyl Sulfosuccinic Acid".
This graph shows the total number of publications written about "Dioctyl Sulfosuccinic Acid" by people in this website by year, and whether "Dioctyl Sulfosuccinic Acid" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 1 | 0 | 1 |
2005 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2016 | 1 | 1 | 2 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dioctyl Sulfosuccinic Acid" by people in Profiles.
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Temkin AM, Bowers RR, Ulmer CZ, Penta K, Bowden JA, Nyland J, Baatz JE, Spyropoulos DD. Increased adiposity, inflammation, metabolic disruption and dyslipidemia in adult male offspring of DOSS treated C57BL/6 dams. Sci Rep. 2019 02 06; 9(1):1530.
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Edenfield AL, Siddiqui NY, Wu JM, Dieter AA, Garrett MA, Visco AG. Polyethylene Glycol 3350 and Docusate Sodium Compared With Docusate Sodium Alone After Urogynecologic Surgery: A Randomized Controlled Trial. Obstet Gynecol. 2016 Sep; 128(3):543-9.
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Bowers RR, Temkin AM, Guillette LJ, Baatz JE, Spyropoulos DD. The commonly used nonionic surfactant Span 80 has RXRa transactivation activity, which likely increases the obesogenic potential of oil dispersants and food emulsifiers. Gen Comp Endocrinol. 2016 11 01; 238:61-68.
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Temkin AM, Bowers RR, Magaletta ME, Holshouser S, Maggi A, Ciana P, Guillette LJ, Bowden JA, Kucklick JR, Baatz JE, Spyropoulos DD. Effects of Crude Oil/Dispersant Mixture and Dispersant Components on PPAR? Activity in Vitro and in Vivo: Identification of Dioctyl Sodium Sulfosuccinate (DOSS; CAS #577-11-7) as a Probable Obesogen. Environ Health Perspect. 2016 Jan; 124(1):112-9.
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Bae WS, Lestage DJ, Proia M, Heinhorst S, Urban MW. Film formation from colloidal dispersions stabilized by sugar derivatives and their controllable release for selective protein adsorption. Biomacromolecules. 2005 Sep-Oct; 6(5):2615-21.
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Lemon HM, Mazyck-Brown J, Cancellaro TA, Darden PM, Basco WT. Review of a randomized trial comparing 2 cerumenolytic agents. Arch Pediatr Adolesc Med. 2003 Dec; 157(12):1181-3.