"Gene Fusion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The GENETIC RECOMBINATION of the parts of two or more GENES resulting in a gene with different or additional regulatory regions, or a new chimeric gene product. ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS. ARTIFICIAL GENE FUSION is carried out in vitro by RECOMBINANT DNA technology.
| Descriptor ID |
D050939
|
| MeSH Number(s) |
G05.728.385
|
| Concept/Terms |
Gene Fusion- Gene Fusion
- Fusion, Gene
- Fusions, Gene
- Gene Fusions
|
Below are MeSH descriptors whose meaning is more general than "Gene Fusion".
Below are MeSH descriptors whose meaning is more specific than "Gene Fusion".
This graph shows the total number of publications written about "Gene Fusion" by people in this website by year, and whether "Gene Fusion" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gene Fusion" by people in Profiles.
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Fusion partners of NTRK3 affect subcellular localization of the fusion kinase and cytomorphology of melanocytes. Mod Pathol. 2021 04; 34(4):735-747.
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C11orf95-RELA fusion present in a primary supratentorial ependymoma and recurrent sarcoma. Brain Tumor Pathol. 2015 Apr; 32(2):105-11.
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Genomic analysis of G protein gamma subunits in human and mouse - the relationship between conserved gene structure and G protein betagamma dimer formation. Cell Signal. 2006 Feb; 18(2):194-201.