"Histone Deacetylase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A histone deacetylase subtype that is found along with HISTONE DEACETYLASE 2; RETINOBLASTOMA-BINDING PROTEIN 4; and RETINOBLASTOMA-BINDING PROTEIN 7 as core components of histone deacetylase complexes.
| Descriptor ID |
D056284
|
| MeSH Number(s) |
D08.811.277.087.520.500.100 D08.811.277.087.520.750.100 D08.811.600.620.100 D08.811.600.795.100
|
| Concept/Terms |
Histone Deacetylase 1- Histone Deacetylase 1
- Deacetylase 1, Histone
- HDAC1 Histone Deacetylase
- Deacetylase, HDAC1 Histone
- Histone Deacetylase, HDAC1
- RPD3L1 Histone Deacetylase
- Deacetylase, RPD3L1 Histone
- Histone Deacetylase, RPD3L1
|
Below are MeSH descriptors whose meaning is more general than "Histone Deacetylase 1".
Below are MeSH descriptors whose meaning is more specific than "Histone Deacetylase 1".
This graph shows the total number of publications written about "Histone Deacetylase 1" by people in this website by year, and whether "Histone Deacetylase 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 4 | 4 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 2 | 4 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 1 | 3 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Histone Deacetylase 1" by people in Profiles.
-
Transcription suppression is mediated by the HDAC1-Sin3 complex in Xenopus nucleoplasmic extract. J Biol Chem. 2022 11; 298(11):102578.
-
Synergism of 4HPR and SAHA increases anti-tumor actions in glioblastoma cells. Apoptosis. 2020 04; 25(3-4):217-232.
-
NF-?B inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model. Nat Commun. 2018 08 24; 9(1):3431.
-
HDAC inhibition helps post-MI healing by modulating macrophage polarization. J Mol Cell Cardiol. 2018 06; 119:51-63.
-
Class I HDAC Inhibitors Display Different Antitumor Mechanism in Leukemia and Prostatic Cancer Cells Depending on Their p53 Status. J Med Chem. 2018 03 22; 61(6):2589-2603.
-
HDAC1 localizes to the mitochondria of cardiac myocytes and contributes to early cardiac reperfusion injury. J Mol Cell Cardiol. 2018 01; 114:309-319.
-
Evidence for a non-canonical role of HDAC5 in regulation of the cardiac Ncx1 and Bnp genes. Nucleic Acids Res. 2016 05 05; 44(8):3610-7.
-
Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia. J Biol Chem. 2016 Feb 19; 291(8):4004-18.
-
Target engagement and drug residence time can be observed in living cells with BRET. Nat Commun. 2015 Dec 03; 6:10091.
-
Inhibition of class I histone deacetylase activity represses matrix metalloproteinase-2 and -9 expression and preserves LV function postmyocardial infarction. Am J Physiol Heart Circ Physiol. 2015 Jun 01; 308(11):H1391-401.