"Angiopoietin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An angiopoietin that is closely related to ANGIOPOIETIN-1. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of ANGIOPOIETIN-1. However its antagonistic effect may be limited to cell receptors that occur within the vasculature. Angiopoietin-2 may therefore play a role in down-regulation of BLOOD VESSEL branching and sprouting.
| Descriptor ID |
D042702
|
| MeSH Number(s) |
D12.644.276.100.100.200 D12.776.467.100.100.200 D23.529.100.100.200
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Angiopoietin-2".
Below are MeSH descriptors whose meaning is more specific than "Angiopoietin-2".
This graph shows the total number of publications written about "Angiopoietin-2" by people in this website by year, and whether "Angiopoietin-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Angiopoietin-2" by people in Profiles.
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Associations of Angiopoietins With Heart Failure Incidence and Severity. J Card Fail. 2021 07; 27(7):786-795.
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Soluble Vascular Cell Adhesion Molecule-1 (sVCAM-1) Is Elevated in Bronchoalveolar Lavage Fluid of Patients with Acute Respiratory Distress Syndrome. PLoS One. 2016; 11(2):e0149687.
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Efficacy of bevacizumab plus erlotinib for advanced hepatocellular carcinoma and predictors of outcome: final results of a phase II trial. Oncology. 2012; 82(2):67-74.
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Host-derived angiopoietin-2 affects early stages of tumor development and vessel maturation but is dispensable for later stages of tumor growth. Cancer Res. 2009 Feb 15; 69(4):1324-33.