Gene Rearrangement, B-Lymphocyte, Heavy Chain
"Gene Rearrangement, B-Lymphocyte, Heavy Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ordered rearrangement of B-lymphocyte variable gene regions of the IMMUNOGLOBULIN HEAVY CHAINS, thereby contributing to antibody diversity. It occurs during the first stage of differentiation of the IMMATURE B-LYMPHOCYTES.
| Descriptor ID |
D015326
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| MeSH Number(s) |
G05.344.401.501 G12.500.274.501
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| Concept/Terms |
Gene Rearrangement, B-Lymphocyte, Heavy Chain- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- B-Cell Heavy Chain Gene Rearrangement
- B-Lymphocyte Heavy Chain Gene Rearrangement
- B Cell Heavy Chain Gene Rearrangement
- B Lymphocyte Heavy Chain Gene Rearrangement
|
Below are MeSH descriptors whose meaning is more general than "Gene Rearrangement, B-Lymphocyte, Heavy Chain".
Below are MeSH descriptors whose meaning is more specific than "Gene Rearrangement, B-Lymphocyte, Heavy Chain".
This graph shows the total number of publications written about "Gene Rearrangement, B-Lymphocyte, Heavy Chain" by people in this website by year, and whether "Gene Rearrangement, B-Lymphocyte, Heavy Chain" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
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Below are the most recent publications written about "Gene Rearrangement, B-Lymphocyte, Heavy Chain" by people in Profiles.
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CD19 negative precursor B acute lymphoblastic leukemia presenting with hypercalcemia. Pediatr Blood Cancer. 2004 Jul; 43(1):66-9.
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Enrichment of anti-glomerular antigen antibody-producing cells in the kidneys of MRL/MpJ-Fas(lpr) mice. J Immunol. 2004 Mar 15; 172(6):3913-21.
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Chronic graft-versus-host in Ig knockin transgenic mice abrogates B cell tolerance in anti-double-stranded DNA B cells. J Immunol. 2002 Apr 15; 168(8):4142-53.
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The origin of anti-nuclear antibodies in bcl-2 transgenic mice. Int Immunol. 2000 Mar; 12(3):353-64.
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Genetic control of DNA antibody production: focus on the heavy chain. Lupus. 1997; 6(3):310-4.
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Development and characterization of channel catfish long term B cell lines. J Immunol. 1994 Mar 01; 152(5):2180-9.
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Molecular characterization of anti-DNA antibodies induced in normal mice by immunization with bacterial DNA. Differences from spontaneous anti-DNA in the content and location of VH CDR3 arginines. J Immunol. 1993 Aug 01; 151(3):1353-64.