Glycation End Products, Advanced

"Glycation End Products, Advanced" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A heterogeneous group of compounds derived from rearrangements, oxidation, and cross-linking reactions that follow from non-enzymatic glycation of amino groups in proteins. They are also know as Maillard products. Their accumulation in vivo accelerates under hyperglycemic, oxidative, or inflammatory conditions. Heat also accelerates the formation of advanced glycation end products (AGEs) such seen with the browning of food during cooking under or over high heat.

Descriptor ID	D017127
MeSH Number(s)	D12.776.643.500
Concept/Terms	Glycation End Products, Advanced Glycation End Products, Advanced Maillard Reaction End Products Maillard Reaction Products Products, Maillard Reaction Reaction Products, Maillard Advanced Maillard Reaction End Products Glycation Endproducts, Advanced Endproducts, Advanced Glycation Glycosylation End Products, Advanced Advanced Glycosylation Endproducts Endproducts, Advanced Glycosylation Glycosylation Endproducts, Advanced Advanced Glycation End Products Advanced Glycosylation End Products Maillard Products Products, Maillard Advanced Glycation Endproducts

Below are MeSH descriptors whose meaning is more general than "Glycation End Products, Advanced".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Protein Degradation End Products [D12.776.643]
Glycation End Products, Advanced [D12.776.643.500]

Below are MeSH descriptors whose meaning is related to "Glycation End Products, Advanced".

Below are MeSH descriptors whose meaning is more specific than "Glycation End Products, Advanced".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Glycation End Products, Advanced" by people in this website by year, and whether "Glycation End Products, Advanced" was a major or minor topic of these publications.

Bar chart showing 56 publications over 26 distinct years, with a maximum of 6 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	0	1	1
1996	1	1	2
1997	1	1	2
1999	0	1	1
2002	2	0	2
2003	1	1	2
2004	0	2	2
2005	2	4	6
2006	1	0	1
2007	0	2	2
2008	1	1	2
2009	2	1	3
2010	3	1	4
2011	1	1	2
2012	2	3	5
2013	2	2	4
2014	1	0	1
2015	1	1	2
2016	2	1	3
2017	1	0	1
2018	1	0	1
2019	0	1	1
2020	2	0	2
2021	2	0	2
2022	0	1	1

Below are the most recent publications written about "Glycation End Products, Advanced" by people in Profiles.

Kinscherf NA, Pehar M. Role and Therapeutic Potential of RAGE Signaling in Neurodegeneration. Curr Drug Targets. 2022; 23(12):1191-1209.

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Omofuma OO, Peterson LL, Turner DP, Merchant AT, Zhang J, Thomson CA, Neuhouser ML, Snetselaar LG, Caan BJ, Shadyab AH, Saquib N, Banack HR, Uribarri J, Steck SE. Dietary Advanced Glycation End-Products and Mortality after Breast Cancer in the Women's Health Initiative. Cancer Epidemiol Biomarkers Prev. 2021 12; 30(12):2217-2226.

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Gregoski MJ, Newton J, Blaylock K, Smith SAO, Turner DP. Examination of the Effectiveness of the Healthy Empowered Active Lifestyles (HEAL) Program on Advanced Glycation End Products. Int J Environ Res Public Health. 2021 05 02; 18(9).

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Omofuma OO, Turner DP, Peterson LL, Merchant AT, Zhang J, Steck SE. Dietary Advanced Glycation End-products (AGE) and Risk of Breast Cancer in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO). Cancer Prev Res (Phila). 2020 07; 13(7):601-610.

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Peterson LL, Park S, Park Y, Colditz GA, Anbardar N, Turner DP. Dietary advanced glycation end products and the risk of postmenopausal breast cancer in the National Institutes of Health-AARP Diet and Health Study. Cancer. 2020 06 01; 126(11):2648-2657.

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Lopes-Virella MF, Bebu I, Hunt KJ, Virella G, Baker NL, Braffett B, Gao X, Lachin JM. Immune Complexes and the Risk of CVD in Type 1 Diabetes. Diabetes. 2019 09; 68(9):1853-1860.

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Walter KR, Ford ME, Gregoski MJ, Kramer RM, Knight KD, Spruill L, Nogueira LM, Krisanits BA, Phan V, La Rue AC, Lilly MB, Ambs S, Chan K, Turner TF, Varner H, Singh S, Uribarri J, Garrett-Mayer E, Armeson KE, Hilton EJ, Clair MJ, Taylor MH, Abbott AM, Findlay VJ, Peterson LL, Magwood G, Turner DP. Advanced glycation end products are elevated in estrogen receptor-positive breast cancer patients, alter response to therapy, and can be targeted by lifestyle intervention. Breast Cancer Res Treat. 2019 Feb; 173(3):559-571.

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LeWinter MM, Taatjes D, Ashikaga T, Palmer B, Bishop N, VanBuren P, Bell S, Donaldson C, Meyer M, Margulies KB, Redfield M, Bull DA, Zile M. Abundance, localization, and functional correlates of the advanced glycation end-product carboxymethyl lysine in human myocardium. Physiol Rep. 2017 Nov; 5(20).

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Turner DP. The Role of Advanced Glycation End-Products in Cancer Disparity. Adv Cancer Res. 2017; 133:1-22.

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Fu D, Yu JY, Yang S, Wu M, Hammad SM, Connell AR, Du M, Chen J, Lyons TJ. Survival or death: a dual role for autophagy in stress-induced pericyte loss in diabetic retinopathy. Diabetologia. 2016 10; 59(10):2251-61.

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