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PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.
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PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.
PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis. Nat Commun. 2021 06 08; 12(1):3444.
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PubMed
subject areas
Animals
Antineoplastic Agents
Arginine
Biocatalysis
Breast Neoplasms
Carcinogenesis
Cell Line, Tumor
Cell Membrane
Cell Proliferation
Enzyme Activation
Female
HEK293 Cells
Humans
Methylation
Mice, Nude
Mutation
Protein Binding
Protein Kinase Inhibitors
Protein-Arginine N-Methyltransferases
Proto-Oncogene Proteins c-akt
RNA, Small Interfering
Signal Transduction
authors with profiles
Lauren Elizabeth Ball
Viswanathan Palanisamy
Shaun K. Olsen
Michael C Ostrowski
Wenjian Gan
Shasha Yin