"Methacholine Chloride" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)
| Descriptor ID |
D016210
|
| MeSH Number(s) |
D02.092.877.883.555.500 D02.675.276.534.500
|
| Concept/Terms |
Methacholine Chloride- Methacholine Chloride
- Chloride, Methacholine
- Acetyl-beta-methacholine Chloride
- Acetyl beta methacholine Chloride
- Mecholine
- 2-(Acetyloxy)-N,N,N-trimethyl-1-propanaminium Chloride
- Acetyl-2-methylcholine Chloride
- Acetyl 2 methylcholine Chloride
|
Below are MeSH descriptors whose meaning is more general than "Methacholine Chloride".
Below are MeSH descriptors whose meaning is more specific than "Methacholine Chloride".
This graph shows the total number of publications written about "Methacholine Chloride" by people in this website by year, and whether "Methacholine Chloride" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 2 | 3 |
| 2016 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Methacholine Chloride" by people in Profiles.
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Kiskurno S, Ryan RM, Paturi B, Wang H, Kumar VH. Antioxidant MnTBAP does not protect adult mice from neonatal hyperoxic lung injury. Respir Physiol Neurobiol. 2020 11; 282:103545.
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Kumar VH, Lakshminrusimha S, Kishkurno S, Paturi BS, Gugino SF, Nielsen L, Wang H, Ryan RM. Neonatal hyperoxia increases airway reactivity and inflammation in adult mice. Pediatr Pulmonol. 2016 11; 51(11):1131-1141.
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Andreoli SM, Schlosser RJ, Wang LF, Mulligan RM, Discolo CM, White DR. Adenoid ciliostimulation in children with chronic otitis media. Otolaryngol Head Neck Surg. 2013 Jan; 148(1):135-9.
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Price MM, Oskeritzian CA, Falanga YT, Harikumar KB, Allegood JC, Alvarez SE, Conrad D, Ryan JJ, Milstien S, Spiegel S. A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell-dependent murine model of allergic asthma. J Allergy Clin Immunol. 2013 Feb; 131(2):501-11.e1.
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Wang LF, White DR, Andreoli SM, Mulligan RM, Discolo CM, Schlosser RJ. Cigarette smoke inhibits dynamic ciliary beat frequency in pediatric adenoid explants. Otolaryngol Head Neck Surg. 2012 Apr; 146(4):659-63.
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Berndt A, Leme AS, Williams LK, Von Smith R, Savage HS, Stearns TM, Tsaih SW, Shapiro SD, Peters LL, Paigen B, Svenson KL. Comparison of unrestrained plethysmography and forced oscillation for identifying genetic variability of airway responsiveness in inbred mice. Physiol Genomics. 2011 Jan 07; 43(1):1-11.
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Brehm JM, Celedón JC, Soto-Quiros ME, Avila L, Hunninghake GM, Forno E, Laskey D, Sylvia JS, Hollis BW, Weiss ST, Litonjua AA. Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica. Am J Respir Crit Care Med. 2009 May 01; 179(9):765-71.
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Stepniakowski KT, Lu G, Davda RK, Egan BM. Fatty acids augment endothelium-dependent dilation in hand veins by a cyclooxygenase-dependent mechanism. Hypertension. 1997 Dec; 30(6):1634-9.
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Yang B, Schlosser RJ, McCaffrey TV. Signal transduction pathways in modulation of ciliary beat frequency by methacholine. Ann Otol Rhinol Laryngol. 1997 Mar; 106(3):230-6.
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Yang B, Schlosser RJ, McCaffrey TV. Dual signal transduction mechanisms modulate ciliary beat frequency in upper airway epithelium. Am J Physiol. 1996 May; 270(5 Pt 1):L745-51.