"Pralidoxime Compounds" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Various salts of a quaternary ammonium oxime that reconstitute inactivated acetylcholinesterase, especially at the neuromuscular junction, and may cause neuromuscular blockade. They are used as antidotes to organophosphorus poisoning as chlorides, iodides, methanesulfonates (mesylates), or other salts.
| Descriptor ID |
D011220
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| MeSH Number(s) |
D02.092.570.665.535
|
| Concept/Terms |
Pralidoxime Compounds- Pralidoxime Compounds
- Compounds, Pralidoxime
- Pyridine Aldoxime Methyl Compounds
- 2-PAM Compounds
- 2 PAM Compounds
- Compounds, 2-PAM
|
Below are MeSH descriptors whose meaning is more general than "Pralidoxime Compounds".
Below are MeSH descriptors whose meaning is more specific than "Pralidoxime Compounds".
This graph shows the total number of publications written about "Pralidoxime Compounds" by people in this website by year, and whether "Pralidoxime Compounds" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pralidoxime Compounds" by people in Profiles.
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Effect of administration method, animal weight and age on the intranasal delivery of drugs to the brain. J Neurosci Methods. 2017 Jul 15; 286:16-21.
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Intranasal delivery of obidoxime to the brain prevents mortality and CNS damage from organophosphate poisoning. Neurotoxicology. 2016 Mar; 53:64-73.
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Regarding "Repeated pulse intramuscular injection of pralidoxime chloride in severe acute organophosphorus pesticide poisoning". Am J Emerg Med. 2013 Dec; 31(12):1711-2.