"Thromboxane-A Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme found predominantly in platelet microsomes. It catalyzes the conversion of PGG(2) and PGH(2) (prostaglandin endoperoxides) to thromboxane A2. EC 5.3.99.5.
| Descriptor ID |
D013930
|
| MeSH Number(s) |
D08.811.399.475.900
|
| Concept/Terms |
Thromboxane-A Synthase- Thromboxane-A Synthase
- Synthase, Thromboxane-A
- Thromboxane A2 Synthetase
- A2 Synthetase, Thromboxane
- Synthetase, Thromboxane A2
- Thromboxane Synthetase
- Synthetase, Thromboxane
- Thromboxane A Synthase
- Synthase, Thromboxane A
|
Below are MeSH descriptors whose meaning is more general than "Thromboxane-A Synthase".
Below are MeSH descriptors whose meaning is more specific than "Thromboxane-A Synthase".
This graph shows the total number of publications written about "Thromboxane-A Synthase" by people in this website by year, and whether "Thromboxane-A Synthase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thromboxane-A Synthase" by people in Profiles.
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Moussa O, Ciupek A, Watson DK, Halushka PV. Urinary thromboxane B2 and thromboxane receptors in bladder cancer: opportunity for detection and monitoring. Prostaglandins Other Lipid Mediat. 2011 Nov; 96(1-4):41-4.
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Moussa O, Riker JM, Klein J, Fraig M, Halushka PV, Watson DK. Inhibition of thromboxane synthase activity modulates bladder cancer cell responses to chemotherapeutic agents. Oncogene. 2008 Jan 03; 27(1):55-62.
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Moussa O, Yordy JS, Abol-Enein H, Sinha D, Bissada NK, Halushka PV, Ghoneim MA, Watson DK. Prognostic and functional significance of thromboxane synthase gene overexpression in invasive bladder cancer. Cancer Res. 2005 Dec 15; 65(24):11581-7.
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DuBois RN. Evaluation of the whole prostaglandin biosynthetic pathway in lung cancer. Clin Cancer Res. 2003 May; 9(5):1577-8.
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Tempel GE, Martin HF. The beneficial effects of a thromboxane receptor antagonist on spinal cord perfusion following experimental cord injury. J Neurol Sci. 1992 Jun; 109(2):162-7.
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Graham LM, Brothers TE, Darvishian D, Harrell KA, Vincent CK, Burkel WE, Stanley JC. Effects of thromboxane synthetase inhibition on patency and anastomotic hyperplasia of vascular grafts. J Surg Res. 1989 Jun; 46(6):611-5.
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Wise WC, Cook JA, Tempel GE, Reines HD, Halushka PV. The rat in sepsis and endotoxic shock. Prog Clin Biol Res. 1989; 299:243-52.
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Tempel GE, Cook JA, Wise WC, Halushka PV, Corral D. Improvement in organ blood flow by inhibition of thromboxane synthetase during experimental endotoxic shock in the rat. J Cardiovasc Pharmacol. 1986 May-Jun; 8(3):514-9.
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Chen ST, Hsu CY, Hogan EL, Halushka PV, Linet OI, Yatsu FM. Thromboxane, prostacyclin, and leukotrienes in cerebral ischemia. Neurology. 1986 Apr; 36(4):466-70.
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Ball HA, Cook JA, Wise WC, Halushka PV. Role of thromboxane, prostaglandins and leukotrienes in endotoxic and septic shock. Intensive Care Med. 1986; 12(3):116-26.