Receptors, Complement 3d

"Receptors, Complement 3d" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Molecular sites on or in B-lymphocytes, follicular dendritic cells, lymphoid cells, and epithelial cells that recognize and combine with COMPLEMENT C3D. Human complement receptor 2 (CR2) serves as a receptor for both C3dg and the gp350/220 glycoprotein of HERPESVIRUS 4, HUMAN, and binds the monoclonal antibody OKB7, which blocks binding of both ligands to the receptor.

Descriptor ID	D017464
MeSH Number(s)	D12.776.543.750.705.833.610 D12.776.543.750.830.250
Concept/Terms	Receptors, Complement 3d Receptors, Complement 3d Herpesvirus 4 Receptors, Human Epstein-Barr Virus Receptor Epstein Barr Virus Receptor Receptor, Epstein-Barr Virus Virus Receptor, Epstein-Barr Receptors, Epstein-Barr Virus Receptors, Epstein Barr Virus Virus Receptors, Epstein-Barr Epstein-Barr Virus Receptors Epstein Barr Virus Receptors C3d Receptors Receptors, C3d CD21 Antigen Antigen, CD21 Antigens, CD21 CD21 Antigens CR2 Receptors Receptors, CR2 CD 21 Antigens Antigens, CD 21 Complement Receptor 2 Receptor 2, Complement Complement Receptors 2 Receptors 2, Complement Complement 3d Receptor Receptor, Complement 3d Complement 3d Receptors

Below are MeSH descriptors whose meaning is more general than "Receptors, Complement 3d".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Complement [D12.776.543.750.705.833]
Receptors, Complement 3d [D12.776.543.750.705.833.610]
Receptors, Virus [D12.776.543.750.830]
Receptors, Complement 3d [D12.776.543.750.830.250]

Below are MeSH descriptors whose meaning is related to "Receptors, Complement 3d".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Complement 3d".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Complement 3d" by people in this website by year, and whether "Receptors, Complement 3d" was a major or minor topic of these publications.

Bar chart showing 27 publications over 12 distinct years, with a maximum of 5 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	1	0	1
2005	0	1	1
2006	1	1	2
2007	3	0	3
2009	3	0	3
2010	1	1	2
2012	4	1	5
2013	1	0	1
2014	2	1	3
2015	3	1	4
2017	1	0	1
2020	0	1	1

Below are the most recent publications written about "Receptors, Complement 3d" by people in Profiles.

Annamalai B, Parsons N, Brandon C, Rohrer B. The use of Matrigel combined with encapsulated cell technology to deliver a complement inhibitor in a mouse model of choroidal neovascularization. Mol Vis. 2020; 26:370-377.

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Schnabolk G, Beon MK, Tomlinson S, Rohrer B. New Insights on Complement Inhibitor CD59 in Mouse Laser-Induced Choroidal Neovascularization: Mislocalization After Injury and Targeted Delivery for Protein Replacement. J Ocul Pharmacol Ther. 2017 06; 33(5):400-411.

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Alawieh A, Elvington A, Zhu H, Yu J, Kindy MS, Atkinson C, Tomlinson S. Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement. J Neuroinflammation. 2015 Dec 30; 12:247.

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Elvington M, Schepp-Berglind J, Tomlinson S. Regulation of the alternative pathway of complement modulates injury and immunity in a chronic model of dextran sulphate sodium-induced colitis. Clin Exp Immunol. 2015 Mar; 179(3):500-8.

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Taylor RL, Cruickshank MN, Karimi M, Ng HL, Quail E, Kaufman KM, Harley JB, Abraham LJ, Tsao BP, Boackle SA, Ulgiati D. Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells. Cell Mol Immunol. 2016 Jan; 13(1):119-31.

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Kulik L, Hewitt FB, Willis VC, Rodriguez R, Tomlinson S, Holers VM. A new mouse anti-mouse complement receptor type 2 and 1 (CR2/CR1) monoclonal antibody as a tool to study receptor involvement in chronic models of immune responses and disease. Mol Immunol. 2015 Feb; 63(2):479-88.

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Zhao J, Giles BM, Taylor RL, Yette GA, Lough KM, Ng HL, Abraham LJ, Wu H, Kelly JA, Glenn SB, Adler AJ, Williams AH, Comeau ME, Ziegler JT, Marion M, Alarcón-Riquelme ME, Alarcón GS, Anaya JM, Bae SC, Kim D, Lee HS, Criswell LA, Freedman BI, Gilkeson GS, Guthridge JM, Jacob CO, James JA, Kamen DL, Merrill JT, Sivils KM, Niewold TB, Petri MA, Ramsey-Goldman R, Reveille JD, Scofield RH, Stevens AM, Vilá LM, Vyse TJ, Kaufman KM, Harley JB, Langefeld CD, Gaffney PM, Brown EE, Edberg JC, Kimberly RP, Ulgiati D, Tsao BP, Boackle SA. Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA. Ann Rheum Dis. 2016 Jan; 75(1):242-52.

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Marshall KM, He S, Zhong Z, Atkinson C, Tomlinson S. Dissecting the complement pathway in hepatic injury and regeneration with a novel protective strategy. J Exp Med. 2014 Aug 25; 211(9):1793-805.

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Benitez A, Weldon AJ, Tatosyan L, Velkuru V, Lee S, Milford TA, Francis OL, Hsu S, Nazeri K, Casiano CM, Schneider R, Gonzalez J, Su RJ, Baez I, Colburn K, Moldovan I, Payne KJ. Differences in mouse and human nonmemory B cell pools. J Immunol. 2014 May 15; 192(10):4610-9.

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Holers VM, Rohrer B, Tomlinson S. CR2-mediated targeting of complement inhibitors: bench-to-bedside using a novel strategy for site-specific complement modulation. Adv Exp Med Biol. 2013; 735:137-54.

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