Macrophage Activation Syndrome
"Macrophage Activation Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serious complication of childhood systemic inflammatory disorders that is thought to be caused by excessive activation and proliferation of T-LYMPHOCYTES and MACROPHAGES. It is seen predominantly in children with systemic onset JUVENILE IDIOPATHIC ARTHRITIS.
| Descriptor ID |
D055501
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| MeSH Number(s) |
C20.683.515.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Macrophage Activation Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Macrophage Activation Syndrome".
This graph shows the total number of publications written about "Macrophage Activation Syndrome" by people in this website by year, and whether "Macrophage Activation Syndrome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Macrophage Activation Syndrome" by people in Profiles.
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Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases. J Clin Invest. 2020 04 01; 130(4):1669-1682.
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Severe cerebral vaso-occlusive disease in macrophage activation syndrome. Pediatr Neurol. 2010 Apr; 42(4):283-6.
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Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis is associated with MUNC13-4 polymorphisms. Arthritis Rheum. 2008 Sep; 58(9):2892-6.