"2-Acetylaminofluorene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
| Descriptor ID |
D015073
|
| MeSH Number(s) |
D02.065.064.150 D02.241.081.018.110.080 D02.455.426.559.847.389.050 D04.615.389.050
|
| Concept/Terms |
2-Acetylaminofluorene- 2-Acetylaminofluorene
- 2 Acetylaminofluorene
- 2-Acetamidofluorene
- 2 Acetamidofluorene
- 2-Fluorenylacetamide
- 2 Fluorenylacetamide
- N-2-Fluorenylacetamide
- N 2 Fluorenylacetamide
- N-Acetyl-2-Aminofluorene
- N Acetyl 2 Aminofluorene
- AAF, Aminofluorene
- Aminofluorene AAF
- 2-AAF
- Fluoren-2-ylacetamide
- Fluoren 2 ylacetamide
|
Below are MeSH descriptors whose meaning is more general than "2-Acetylaminofluorene".
Below are MeSH descriptors whose meaning is more specific than "2-Acetylaminofluorene".
This graph shows the total number of publications written about "2-Acetylaminofluorene" by people in this website by year, and whether "2-Acetylaminofluorene" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "2-Acetylaminofluorene" by people in Profiles.
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Oval cell response is attenuated by depletion of liver resident macrophages in the 2-AAF/partial hepatectomy rat. PLoS One. 2012; 7(4):e35180.
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Modeling time-to-tumor data: analysis of the ED01 study. Fundam Appl Toxicol. 1983 Sep-Oct; 3(5):458-69.
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Multistage prediction of cancer in serially dosed animals with application to the ED01 study. Fundam Appl Toxicol. 1983 Sep-Oct; 3(5):470-7.