"2-Acetylaminofluorene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
| Descriptor ID |
D015073
|
| MeSH Number(s) |
D02.065.064.150 D02.241.081.018.110.080 D02.455.426.559.847.389.050 D04.615.389.050
|
| Concept/Terms |
2-Acetylaminofluorene- 2-Acetylaminofluorene
- 2 Acetylaminofluorene
- 2-Acetamidofluorene
- 2 Acetamidofluorene
- 2-Fluorenylacetamide
- 2 Fluorenylacetamide
- N-2-Fluorenylacetamide
- N 2 Fluorenylacetamide
- N-Acetyl-2-Aminofluorene
- N Acetyl 2 Aminofluorene
- AAF, Aminofluorene
- Aminofluorene AAF
- 2-AAF
- Fluoren-2-ylacetamide
- Fluoren 2 ylacetamide
|
Below are MeSH descriptors whose meaning is more general than "2-Acetylaminofluorene".
Below are MeSH descriptors whose meaning is more specific than "2-Acetylaminofluorene".
This graph shows the total number of publications written about "2-Acetylaminofluorene" by people in this website by year, and whether "2-Acetylaminofluorene" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "2-Acetylaminofluorene" by people in Profiles.
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Xiang S, Dong HH, Liang HF, He SQ, Zhang W, Li CH, Zhang BX, Zhang BH, Jing K, Tomlinson S, van Rooijen N, Jiang L, Cianflone K, Chen XP. Oval cell response is attenuated by depletion of liver resident macrophages in the 2-AAF/partial hepatectomy rat. PLoS One. 2012; 7(4):e35180.
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Brown KG, Hoel DG. Modeling time-to-tumor data: analysis of the ED01 study. Fundam Appl Toxicol. 1983 Sep-Oct; 3(5):458-69.
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Brown KG, Hoel DG. Multistage prediction of cancer in serially dosed animals with application to the ED01 study. Fundam Appl Toxicol. 1983 Sep-Oct; 3(5):470-7.