Paralysis, Hyperkalemic Periodic
"Paralysis, Hyperkalemic Periodic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autosomal dominant familial disorder which presents in infancy or childhood and is characterized by episodes of weakness associated with hyperkalemia. During attacks, muscles of the lower extremities are initially affected, followed by the lower trunk and arms. Episodes last from 15-60 minutes and typically occur after a period of rest following exercise. A defect in skeletal muscle sodium channels has been identified as the cause of this condition. Normokalemic periodic paralysis is a closely related disorder marked by a lack of alterations in potassium levels during attacks of weakness. (Adams et al., Principles of Neurology, 6th ed, p1481)
| Descriptor ID |
D020513
|
| MeSH Number(s) |
C05.651.701.600 C10.668.491.650.600 C16.320.565.618.711.600 C18.452.648.618.711.600
|
| Concept/Terms |
Paralysis, Hyperkalemic Periodic- Paralysis, Hyperkalemic Periodic
- Adynamia Episodica Hereditaria with or without Myotonia
- Familial Hyperkalemic Periodic Paralysis
- Gamstorp Disease
- Disease, Gamstorp
- Gamstorp Episodic Adynamy
- Sodium Channel Muscle Disease
- Hyperkalemic Periodic Paralysis, Familial
- HyperKPP
- HyperPP
- Myotonic Periodic Paralysis
- Paralysis, Periodic, Hyperkalemic, Familial
- Primary Hyperkalemic Periodic Paralysis
- Adynamia Episodica Hereditaria
- Hyperkalemic Periodic Paralysis
|
Below are MeSH descriptors whose meaning is more general than "Paralysis, Hyperkalemic Periodic".
- Diseases [C]
- Musculoskeletal Diseases [C05]
- Muscular Diseases [C05.651]
- Paralyses, Familial Periodic [C05.651.701]
- Paralysis, Hyperkalemic Periodic [C05.651.701.600]
- Nervous System Diseases [C10]
- Neuromuscular Diseases [C10.668]
- Muscular Diseases [C10.668.491]
- Paralyses, Familial Periodic [C10.668.491.650]
- Paralysis, Hyperkalemic Periodic [C10.668.491.650.600]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Metabolism, Inborn Errors [C16.320.565]
- Metal Metabolism, Inborn Errors [C16.320.565.618]
- Paralyses, Familial Periodic [C16.320.565.618.711]
- Paralysis, Hyperkalemic Periodic [C16.320.565.618.711.600]
- Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
- Metabolism, Inborn Errors [C18.452.648]
- Metal Metabolism, Inborn Errors [C18.452.648.618]
- Paralyses, Familial Periodic [C18.452.648.618.711]
- Paralysis, Hyperkalemic Periodic [C18.452.648.618.711.600]
Below are MeSH descriptors whose meaning is more specific than "Paralysis, Hyperkalemic Periodic".
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