Immunoglobulin M

"Immunoglobulin M" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally being called a macroglobulin.

Descriptor ID	D007075
MeSH Number(s)	D12.776.124.486.485.114.619.574 D12.776.124.790.651.114.619.574 D12.776.377.715.548.114.619.574
Concept/Terms	Immunoglobulin M Immunoglobulin M Gamma Globulin, 19S 19S Gamma Globulin IgM IgM2 IgM2 IgM1 IgM1

Below are MeSH descriptors whose meaning is more general than "Immunoglobulin M".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Immunoproteins [D12.776.124.486]
Immunoglobulins [D12.776.124.486.485]
Antibodies [D12.776.124.486.485.114]
Immunoglobulin Isotypes [D12.776.124.486.485.114.619]
Immunoglobulin M [D12.776.124.486.485.114.619.574]
Serum Globulins [D12.776.124.790]
Immunoglobulins [D12.776.124.790.651]
Antibodies [D12.776.124.790.651.114]
Immunoglobulin Isotypes [D12.776.124.790.651.114.619]
Immunoglobulin M [D12.776.124.790.651.114.619.574]
Globulins [D12.776.377]
Serum Globulins [D12.776.377.715]
Immunoglobulins [D12.776.377.715.548]
Antibodies [D12.776.377.715.548.114]
Immunoglobulin Isotypes [D12.776.377.715.548.114.619]
Immunoglobulin M [D12.776.377.715.548.114.619.574]

Below are MeSH descriptors whose meaning is related to "Immunoglobulin M".

Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin M".

Immunoglobulin M
Immunoglobulin mu-Chains

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Immunoglobulin M" by people in this website by year, and whether "Immunoglobulin M" was a major or minor topic of these publications.

Bar chart showing 78 publications over 29 distinct years, with a maximum of 7 publications in 1999

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	2	1	3
1994	0	1	1
1995	2	0	2
1996	0	3	3
1997	1	3	4
1998	0	1	1
1999	2	5	7
2000	0	2	2
2001	0	2	2
2002	1	0	1
2003	0	1	1
2004	2	0	2
2005	0	2	2
2006	0	3	3
2007	3	3	6
2008	2	4	6
2009	1	2	3
2010	1	1	2
2011	2	2	4
2013	3	2	5
2014	0	2	2
2015	1	0	1
2016	1	0	1
2017	2	1	3
2018	0	3	3
2019	2	0	2
2020	1	0	1
2021	1	3	4
2022	0	1	1

Below are the most recent publications written about "Immunoglobulin M" by people in Profiles.

Ning W, Cheng D, Howe PH, Bian C, Kamen DL, Luo Z, Fu X, Ogunrinde E, Yang L, Wang X, Li QZ, Oates J, Zhang W, White D, Wan Z, Gilkeson GS, Jiang W. Staphylococcus aureus peptidoglycan (PGN) induces pathogenic autoantibody production via autoreactive B cell receptor clonal selection, implications in systemic lupus erythematosus. J Autoimmun. 2022 07; 131:102860.

View in: PubMed
Phan HD, Longjohn MN, Gormley DJB, Smith RH, Dang-Lawson M, Matsuuchi L, Gold MR, Christian SL. CD24 and IgM Stimulation of B Cells Triggers Transfer of Functional B Cell Receptor to B Cell Recipients Via Extracellular Vesicles. J Immunol. 2021 12 15; 207(12):3004-3015.

View in: PubMed
Annamalai B, Parsons N, Nicholson C, Joseph K, Coughlin B, Yang X, Jones BW, Tomlinson S, Rohrer B. Natural immunoglobulin M-based delivery of a complement alternative pathway inhibitor in mouse models of retinal degeneration. Exp Eye Res. 2021 06; 207:108583.

View in: PubMed
Zhang Z, Wang X, Wei X, Zheng SW, Lenhart BJ, Xu P, Li J, Pan J, Albrecht H, Liu C. Multiplex quantitative detection of SARS-CoV-2 specific IgG and IgM antibodies based on DNA-assisted nanopore sensing. Biosens Bioelectron. 2021 Jun 01; 181:113134.

View in: PubMed
Li C, Patel K, Tu Z, Yang X, Kulik L, Alawieh A, Allen P, Cheng Q, Wallace C, Kilkenny J, Kwon J, Gibney B, Cantu E, Sharma A, Pipkin M, Machuca T, Emtiazjoo A, Goddard M, Holers VM, Nadig S, Christie J, Tomlinson S, Atkinson C. A novel injury site-natural antibody targeted complement inhibitor protects against lung transplant injury. Am J Transplant. 2021 06; 21(6):2067-2078.

View in: PubMed
Banda NK, Tomlinson S, Scheinman RI, Ho N, Ramirez JR, Mehta G, Wang G, Vu VP, Simberg D, Kulik L, Holers VM. C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Attenuates Arthritis in Mice. Front Immunol. 2020; 11:575154.

View in: PubMed
Bailey JD, Fisher AD, Yazer MH, Howard JT, Corley JB, Miles EA, Cap AP. Changes in donor antibody titer levels over time in a military group O low-titer whole blood program. Transfusion. 2019 04; 59(S2):1499-1506.

View in: PubMed
Rourk AR, Litwin CM. Evaluation of the BioPlex 2200 syphilis total screen (IgG/IgM) with reflex to an automated rapid plasma reagin test. J Clin Lab Anal. 2019 Jun; 33(5):e22878.

View in: PubMed
Wang M, Shen J, Herrera H, Singal A, Swindell C, Renquan L, Mehta A. Biomarker analysis of fucosylated kininogen through depletion of lectin reactive heterophilic antibodies in hepatocellular carcinoma. J Immunol Methods. 2018 11; 462:59-64.

View in: PubMed
Alawieh A, Andersen M, Adkins DL, Tomlinson S. Acute Complement Inhibition Potentiates Neurorehabilitation and Enhances tPA-Mediated Neuroprotection. J Neurosci. 2018 07 18; 38(29):6527-6545.

View in: PubMed

People

Explore

Similar Concepts

Top Journals