"Neural Tube Defects" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)
| Descriptor ID |
D009436
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| MeSH Number(s) |
C10.500.680 C16.131.666.680
|
| Concept/Terms |
Neural Tube Defects- Neural Tube Defects
- Defect, Neural Tube
- Defects, Neural Tube
- Neural Tube Defect
- Developmental Neural Tube Defects
- Neural Tube Developmental Defects
- Developmental Defects, Neural Tube
Tethered Cord Syndrome- Tethered Cord Syndrome
- Tethered Cord Syndromes
- Occult Spinal Dysraphism Sequence
- Tethered Spinal Cord Syndrome
- Occult Spinal Dysraphism
- Dysraphism, Occult Spinal
- Dysraphisms, Occult Spinal
- Occult Spinal Dysraphisms
- Spinal Dysraphism, Occult
- Spinal Dysraphisms, Occult
Neurenteric Cyst- Neurenteric Cyst
- Cyst, Neurenteric
- Cysts, Neurenteric
- Neurenteric Cysts
- Neuroenteric Cyst
- Cyst, Neuroenteric
- Cysts, Neuroenteric
- Neuroenteric Cysts
Spinal Cord Myelodysplasia- Spinal Cord Myelodysplasia
- Myelodysplasia, Spinal Cord
- Myelodysplasias, Spinal Cord
- Spinal Cord Myelodysplasias
|
Below are MeSH descriptors whose meaning is more general than "Neural Tube Defects".
Below are MeSH descriptors whose meaning is more specific than "Neural Tube Defects".
This graph shows the total number of publications written about "Neural Tube Defects" by people in this website by year, and whether "Neural Tube Defects" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neural Tube Defects" by people in Profiles.
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Prenatal serum screening for Down syndrome and neural tube defects in the United States: Changes in utilization patterns from 2012 to 2020. J Med Screen. 2021 12; 28(4):405-410.
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Laboratory screening and diagnosis of open neural tube defects, 2019 revision: a technical standard of the American College of Medical Genetics and Genomics (ACMG). Genet Med. 2020 03; 22(3):462-474.
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Global folate status in women of reproductive age: a systematic review with emphasis on methodological issues. Ann N Y Acad Sci. 2018 11; 1431(1):35-57.
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Key apoptotic genes APAF1 and CASP9 implicated in recurrent folate-resistant neural tube defects. Eur J Hum Genet. 2018 03; 26(3):420-427.
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Applying inappropriate cutoffs leads to misinterpretation of folate status in the US population. Am J Clin Nutr. 2016 12; 104(6):1607-1615.
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Optimal serum and red blood cell folate concentrations in women of reproductive age for prevention of neural tube defects: World Health Organization guidelines. MMWR Morb Mortal Wkly Rep. 2015 Apr 24; 64(15):421-3.
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Folic acid in pregnancy and mortality from cancer and cardiovascular disease: further follow-up of the Aberdeen folic acid supplementation trial. J Epidemiol Community Health. 2015 Aug; 69(8):789-94.
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Maternal obesity, folate intake, and neural tube defects in offspring. Birth Defects Res A Clin Mol Teratol. 2013 Feb; 97(2):115-22.
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Concurrent orthopedic and neurosurgical procedures in pediatric patients with spinal deformity. J Pediatr Orthop B. 2012 Nov; 21(6):602-5.
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Resveratrol prevents impairment in activation of retinoic acid receptors and MAP kinases in the embryos of a rodent model of diabetic embryopathy. Reprod Sci. 2012 Sep; 19(9):949-61.