Protein Structure, Tertiary
"Protein Structure, Tertiary" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The level of protein structure in which combinations of secondary protein structures (ALPHA HELICES; BETA SHEETS; loop regions, and AMINO ACID MOTIFS) pack together to form folded shapes. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure.
| Descriptor ID |
D017434
|
| MeSH Number(s) |
G02.111.570.820.709.610
|
| Concept/Terms |
Protein Structure, Tertiary- Protein Structure, Tertiary
- Tertiary Protein Structure
- Protein Structures, Tertiary
- Tertiary Protein Structures
|
Below are MeSH descriptors whose meaning is more general than "Protein Structure, Tertiary".
Below are MeSH descriptors whose meaning is more specific than "Protein Structure, Tertiary".
This graph shows the total number of publications written about "Protein Structure, Tertiary" by people in this website by year, and whether "Protein Structure, Tertiary" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1996 | 0 | 4 | 4 |
| 1998 | 0 | 3 | 3 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 6 | 6 |
| 2001 | 0 | 11 | 11 |
| 2002 | 0 | 12 | 12 |
| 2003 | 0 | 25 | 25 |
| 2004 | 1 | 27 | 28 |
| 2005 | 2 | 20 | 22 |
| 2006 | 2 | 15 | 17 |
| 2007 | 0 | 22 | 22 |
| 2008 | 0 | 12 | 12 |
| 2009 | 0 | 20 | 20 |
| 2010 | 0 | 14 | 14 |
| 2011 | 2 | 12 | 14 |
| 2012 | 0 | 8 | 8 |
| 2013 | 0 | 12 | 12 |
| 2014 | 0 | 14 | 14 |
| 2015 | 0 | 13 | 13 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 4 | 4 |
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Below are the most recent publications written about "Protein Structure, Tertiary" by people in Profiles.
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Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE. Eur J Med Chem. 2022 Jan 05; 227:113926.
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Identification of a potent Nrf2 displacement activator among aspirin-containing prodrugs. Neurochem Int. 2021 10; 149:105148.
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Alternative Splicing Increases Sirtuin Gene Family Diversity and Modulates Their Subcellular Localization and Function. Int J Mol Sci. 2021 Jan 06; 22(2).
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Probing Interdomain Linkers and Protein Supertertiary Structure In Vitro and in Live Cells with Fluorescent Protein Resonance Energy Transfer. J Mol Biol. 2021 03 05; 433(5):166793.
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Resolving dynamics and function of transient states in single enzyme molecules. Nat Commun. 2020 03 06; 11(1):1231.
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Dynamic allostery-based molecular workings of kinase:peptide complexes. Proc Natl Acad Sci U S A. 2019 07 23; 116(30):15052-15061.
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Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation. Nat Commun. 2019 04 11; 10(1):1676.
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Comparative analysis of interactions between aryl hydrocarbon receptor ligand binding domain with its ligands: a computational study. BMC Struct Biol. 2018 12 06; 18(1):15.
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Functional architecture of the Reb1-Ter complex of Schizosaccharomyces pombe. Proc Natl Acad Sci U S A. 2016 Apr 19; 113(16):E2267-76.
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Disruption of S2-M4 linker coupling reveals novel subunit-specific contributions to N-methyl-d-aspartate receptor function and ethanol sensitivity. Neuropharmacology. 2016 06; 105:96-105.