"Langerhans Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recirculating, dendritic, antigen-presenting cells containing characteristic racket-shaped granules (Birbeck granules). They are found principally in the stratum spinosum of the EPIDERMIS and are rich in Class II MAJOR HISTOCOMPATIBILITY COMPLEX molecules. Langerhans cells were the first dendritic cell to be described and have been a model of study for other dendritic cells (DCs), especially other migrating DCs such as dermal DCs and INTERSTITIAL DENDRITIC CELLS.
| Descriptor ID |
D007801
|
| MeSH Number(s) |
A11.066.270.500 A11.436.270.545 A15.382.066.270.500 A15.382.812.260.500
|
| Concept/Terms |
Langerhans Cells- Langerhans Cells
- Cells, Langerhans
- Epidermal Dendritic Cells
- Dendritic Cells, Epidermal
- Cell, Epidermal Dendritic
- Cells, Epidermal Dendritic
- Dendritic Cell, Epidermal
- Epidermal Dendritic Cell
Skin Dendritic Cells- Skin Dendritic Cells
- Cell, Skin Dendritic
- Cells, Skin Dendritic
- Dendritic Cell, Skin
- Skin Dendritic Cell
- Dendritic Cells, Skin
Dermal Dendritic Cells- Dermal Dendritic Cells
- Cell, Dermal Dendritic
- Cells, Dermal Dendritic
- Dendritic Cell, Dermal
- Dermal Dendritic Cell
- Dendritic Cells, Dermal
|
Below are MeSH descriptors whose meaning is more general than "Langerhans Cells".
Below are MeSH descriptors whose meaning is more specific than "Langerhans Cells".
This graph shows the total number of publications written about "Langerhans Cells" by people in this website by year, and whether "Langerhans Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 3 | 0 | 3 |
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Below are the most recent publications written about "Langerhans Cells" by people in Profiles.
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Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2. Eur J Immunol. 2014 Feb; 44(2):553-60.
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Identification of bone morphogenetic protein 7 (BMP7) as an instructive factor for human epidermal Langerhans cell differentiation. J Exp Med. 2013 Nov 18; 210(12):2597-610.
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?-Catenin promotes the differentiation of epidermal Langerhans dendritic cells. J Invest Dermatol. 2013 May; 133(5):1250-9.
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Identification of Axl as a downstream effector of TGF-?1 during Langerhans cell differentiation and epidermal homeostasis. J Exp Med. 2012 Oct 22; 209(11):2033-47.
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Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-?1-dependent human epidermal Langerhans cells. J Invest Dermatol. 2011 Oct; 131(10):2049-57.
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Langerhans cell sarcoma. Am J Dermatopathol. 2006 Feb; 28(1):36-9.
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Microtubule-dependent redistribution of a cytoplasmic cornified envelope precursor. J Invest Dermatol. 2004 Jan; 122(1):29-38.
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A new method for the comprehensive automatic morphologic image analysis of Langerhans cells. Am J Dermatopathol. 1988 Oct; 10(5):410-4.
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The effect of aging and chronic sun exposure on human Langerhans cell populations. J Invest Dermatol. 1984 Mar; 82(3):223-6.
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The Langerhans cell. J Am Acad Dermatol. 1982 Apr; 6(4 Pt 1):519-22.