"Cephalosporins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.
| Descriptor ID |
D002511
|
| MeSH Number(s) |
D02.065.589.099.249 D02.886.665.074 D03.633.100.300.249
|
| Concept/Terms |
Cephalosporins- Cephalosporins
- Antibiotics, Cephalosporin
- Cephalosporin Antibiotics
|
Below are MeSH descriptors whose meaning is more general than "Cephalosporins".
Below are MeSH descriptors whose meaning is more specific than "Cephalosporins".
This graph shows the total number of publications written about "Cephalosporins" by people in this website by year, and whether "Cephalosporins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 2 | 0 | 2 |
| 1996 | 1 | 1 | 2 |
| 1997 | 2 | 0 | 2 |
| 1998 | 2 | 0 | 2 |
| 1999 | 3 | 0 | 3 |
| 2000 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 2 | 3 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 2 | 0 | 2 |
| 2021 | 0 | 3 | 3 |
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Below are the most recent publications written about "Cephalosporins" by people in Profiles.
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Warner NC, Bartelt LA, Lachiewicz AM, Tompkins KM, Miller MB, Alby K, Jones MB, Carr AL, Alexander J, Gainey AB, Daniels R, Burch AK, Brown DE, Brownstein MJ, Cheema F, Linder KE, Shields RK, Longworth S, van Duin D. Cefiderocol for the Treatment of Adult and Pediatric Patients With Cystic Fibrosis and Achromobacter xylosoxidans Infections. Clin Infect Dis. 2021 10 05; 73(7):e1754-e1757.
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Al-Hasan MN. Gram-negative Bacteria With Difficult-to-Treat Resistance: A Moving Target. Clin Infect Dis. 2021 06 15; 72(12):2121-2123.
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Turner JM, Connolly KL, Aberman KE, Fonseca JC, Singh A, Jerse AE, Nicholas RA, Davies C. Molecular Features of Cephalosporins Important for Activity against Antimicrobial-Resistant Neisseria gonorrhoeae. ACS Infect Dis. 2021 02 12; 7(2):293-308.
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Sheffield M, Nelson D, O'Neal M, Gould AP, Bouchard J, Nicolau D, Justo JA, Hucks J, Bookstaver PB. Use of continuous-infusion ceftolozane/tazobactam for resistant Gram-negative bacterial infections: a retrospective analysis and brief review of the literature. Int J Antimicrob Agents. 2020 Nov; 56(5):106158.
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Gainey AB, Burch AK, Brownstein MJ, Brown DE, Fackler J, Horne B, Biswas B, Bivens BN, Malagon F, Daniels R. Combining bacteriophages with cefiderocol and meropenem/vaborbactam to treat a pan-drug resistant Achromobacter species infection in a pediatric cystic fibrosis patient. Pediatr Pulmonol. 2020 11; 55(11):2990-2994.
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Singh A, Tomberg J, Nicholas RA, Davies C. Recognition of the ß-lactam carboxylate triggers acylation of Neisseria gonorrhoeae penicillin-binding protein 2. J Biol Chem. 2019 09 20; 294(38):14020-14032.
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Elizabeth Davis S, Ham J, Hucks J, Gould A, Foster R, Ann Justo J, Nicolau DP, Bookstaver PB. Use of continuous infusion ceftolozane-tazobactam with therapeutic drug monitoring in a patient with cystic fibrosis. Am J Health Syst Pharm. 2019 Apr 08; 76(8):501-504.
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MacVane SH, Pandey R, Steed LL, Kreiswirth BN, Chen L. Emergence of Ceftolozane-Tazobactam-Resistant Pseudomonas aeruginosa during Treatment Is Mediated by a Single AmpC Structural Mutation. Antimicrob Agents Chemother. 2017 12; 61(12).
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Majewski MW, Miller PA, Miller MJ. Studies at the ionizable position of cephalosporins and penicillins: hydroxamates as substitutes for the traditional carboxylate group. J Antibiot (Tokyo). 2017 Mar; 70(3):292-296.
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Hammond DA, Smith MN, Painter JT, Meena NK, Lusardi K. Comparative Incidence of Acute Kidney Injury in Critically Ill Patients Receiving Vancomycin with Concomitant Piperacillin-Tazobactam or Cefepime: A Retrospective Cohort Study. Pharmacotherapy. 2016 05; 36(5):463-71.