Growth Differentiation Factor 1
"Growth Differentiation Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A growth differentiation factor that plays a role in the genesis of left-right asymmetry during vertebrate development. Evidence for this role is seen in MICE where loss of growth differentiation factor 1 function results in right-left isomerism of visceral organs. In HUMANS heterozygous loss of growth differentiation factor 1 function has been associated with CONGENITAL HEART DEFECTS and TRANSPOSITION OF GREAT VESSELS.
Descriptor ID |
D055452
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MeSH Number(s) |
D12.644.276.954.300.100 D12.644.276.954.550.100 D12.776.467.942.300.100 D12.776.467.942.550.100 D23.529.942.300.100 D23.529.942.550.100
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Concept/Terms |
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