"Neuraminidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the hydrolysis of alpha-2,3, alpha-2,6-, and alpha-2,8-glycosidic linkages (at a decreasing rate, respectively) of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid, and synthetic substrate. (From Enzyme Nomenclature, 1992)
| Descriptor ID |
D009439
|
| MeSH Number(s) |
D08.811.277.450.692
|
| Concept/Terms |
Neuraminidase- Neuraminidase
- Exo-alpha-Sialidase
- Exo alpha Sialidase
- Sialidase
- N-Acylneuraminate Glycohydrolases
- Glycohydrolases, N-Acylneuraminate
- N Acylneuraminate Glycohydrolases
- Oligosaccharide Sialidase
- Sialidase, Oligosaccharide
|
Below are MeSH descriptors whose meaning is more general than "Neuraminidase".
Below are MeSH descriptors whose meaning is more specific than "Neuraminidase".
This graph shows the total number of publications written about "Neuraminidase" by people in this website by year, and whether "Neuraminidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2005 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neuraminidase" by people in Profiles.
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Novel Combined Enzymatic Approach to Analyze Nonsialylated N-Linked Glycans through MALDI Imaging Mass Spectrometry. J Proteome Res. 2022 08 05; 21(8):1930-1938.
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The role of neuraminidase 1 (NEU1) in cytokine release by primary mouse mesangial cells and disease outcomes in murine lupus nephritis. Autoimmunity. 2021 05; 54(3):163-175.
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The role of neuraminidase in TLR4-MAPK signalling and the release of cytokines by lupus serum-stimulated mesangial cells. Immunology. 2021 04; 162(4):418-433.
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Targeting glycosphingolipid metabolism as a potential therapeutic approach for treating disease in female MRL/lpr lupus mice. PLoS One. 2020; 15(3):e0230499.
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Neuraminidase activity mediates IL-6 production by activated lupus-prone mesangial cells. Am J Physiol Renal Physiol. 2018 04 01; 314(4):F630-F642.
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Desialylation of Neisseria gonorrhoeae Lipooligosaccharide by Cervicovaginal Microbiome Sialidases: The Potential for Enhancing Infectivity in Men. J Infect Dis. 2016 Dec 01; 214(11):1621-1628.
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FLI1 Levels Impact CXCR3 Expression and Renal Infiltration of T Cells and Renal Glycosphingolipid Metabolism in the MRL/lpr Lupus Mouse Strain. J Immunol. 2015 Dec 15; 195(12):5551-60.
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Renal glycosphingolipid metabolism is dysfunctional in lupus nephritis. J Am Soc Nephrol. 2015 Jun; 26(6):1402-13.
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Effects of elevated ammonium on glycosylation gene expression in CHO cells. Metab Eng. 2006 Mar; 8(2):123-32.
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The run on tamiflu--should physicians prescribe on demand? N Engl J Med. 2005 Dec 22; 353(25):2636-7.