Connection

Co-Authors

This is a "connection" page, showing publications co-authored by Gustavo Leone and Michael Ostrowski.
Connection Strength

4.423
  1. The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis. Nat Commun. 2023 01 03; 14(1):1.
    View in: PubMed
    Score: 0.219
  2. Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner. Mol Cancer Res. 2022 08 05; 20(8):1233-1246.
    View in: PubMed
    Score: 0.212
  3. STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer. Life Sci Alliance. 2022 11; 5(11).
    View in: PubMed
    Score: 0.211
  4. Origin, activation and heterogeneity of fibroblasts associated with pancreas and breast cancers. Adv Cancer Res. 2022; 154:169-201.
    View in: PubMed
    Score: 0.207
  5. PTEN in the Stroma. Cold Spring Harb Perspect Med. 2019 10 01; 9(10).
    View in: PubMed
    Score: 0.174
  6. Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation. Cell Rep. 2019 06 18; 27(12):3547-3560.e5.
    View in: PubMed
    Score: 0.170
  7. Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth. Life Sci Alliance. 2018 Oct; 1(5):e201800190.
    View in: PubMed
    Score: 0.164
  8. Stromal PTEN determines mammary epithelial response to radiotherapy. Nat Commun. 2018 07 17; 9(1):2783.
    View in: PubMed
    Score: 0.160
  9. Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1. Oncogene. 2017 11 23; 36(47):6658.
    View in: PubMed
    Score: 0.152
  10. Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele. PLoS One. 2017; 12(9):e0184984.
    View in: PubMed
    Score: 0.152
  11. Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation. Dev Cell. 2017 05 22; 41(4):392-407.e6.
    View in: PubMed
    Score: 0.148
  12. Stromal PDGFR-a Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth. Neoplasia. 2017 Jun; 19(6):496-508.
    View in: PubMed
    Score: 0.148
  13. Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1. Oncogene. 2017 04 20; 36(16):2297-2308.
    View in: PubMed
    Score: 0.143
  14. Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia. Genes Dev. 2016 09 01; 30(17):1943-55.
    View in: PubMed
    Score: 0.141
  15. Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia. Neoplasia. 2016 09; 18(9):541-52.
    View in: PubMed
    Score: 0.141
  16. E2f3 in tumor macrophages promotes lung metastasis. Oncogene. 2016 07 14; 35(28):3636-46.
    View in: PubMed
    Score: 0.133
  17. Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo. Genes Dev. 2015 Aug 15; 29(16):1707-20.
    View in: PubMed
    Score: 0.131
  18. CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth. Oncogene. 2015 Jul; 34(28):3651-61.
    View in: PubMed
    Score: 0.123
  19. Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer. PLoS One. 2013; 8(8):e71533.
    View in: PubMed
    Score: 0.114
  20. Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. Nat Cell Biol. 2011 Dec 18; 14(2):159-67.
    View in: PubMed
    Score: 0.102
  21. Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution. Cancer Res. 2011 Feb 15; 71(4):1203-7.
    View in: PubMed
    Score: 0.096
  22. E2f1-3 are critical for myeloid development. J Biol Chem. 2011 Feb 11; 286(6):4783-95.
    View in: PubMed
    Score: 0.095
  23. Allele-specific tumor spectrum in pten knockin mice. Proc Natl Acad Sci U S A. 2010 Mar 16; 107(11):5142-7.
    View in: PubMed
    Score: 0.090
  24. An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis. Cancer Res. 2010 Feb 15; 70(4):1323-33.
    View in: PubMed
    Score: 0.089
  25. Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis. PLoS One. 2009 Dec 14; 4(12):e8283.
    View in: PubMed
    Score: 0.088
  26. Pten in stromal fibroblasts suppresses mammary epithelial tumours. Nature. 2009 Oct 22; 461(7267):1084-91.
    View in: PubMed
    Score: 0.088
  27. Genomic alterations in tumor stroma. Cancer Res. 2009 Sep 01; 69(17):6759-64.
    View in: PubMed
    Score: 0.087
  28. Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis. Blood. 2009 Jul 30; 114(5):1123-30.
    View in: PubMed
    Score: 0.085
  29. Tensor classification of N-point correlation function features for histology tissue segmentation. Med Image Anal. 2009 Feb; 13(1):156-66.
    View in: PubMed
    Score: 0.080
  30. Direct evidence for epithelial-mesenchymal transitions in breast cancer. Cancer Res. 2008 Feb 01; 68(3):937-45.
    View in: PubMed
    Score: 0.078
  31. Extra-embryonic function of Rb is essential for embryonic development and viability. Nature. 2003 Feb 27; 421(6926):942-7.
    View in: PubMed
    Score: 0.055
  32. Stromal Platelet-Derived Growth Factor Receptor-? Signaling Promotes Breast Cancer Metastasis in the Brain. Cancer Res. 2021 02 01; 81(3):606-618.
    View in: PubMed
    Score: 0.045
  33. Modeling Human Cancer-induced Cachexia. Cell Rep. 2019 08 06; 28(6):1612-1622.e4.
    View in: PubMed
    Score: 0.043
  34. Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression. Cancer Res. 2019 08 15; 79(16):4124-4134.
    View in: PubMed
    Score: 0.043
  35. Fibroblast-derived CXCL12 promotes breast cancer metastasis by facilitating tumor cell intravasation. Oncogene. 2018 08; 37(32):4428-4442.
    View in: PubMed
    Score: 0.040
  36. A hedgehog pathway-dependent gene signature is associated with poor clinical outcomes in Luminal A breast cancer. Breast Cancer Res Treat. 2018 Jun; 169(3):457-467.
    View in: PubMed
    Score: 0.039
  37. IL-18 Drives ILC3 Proliferation and Promotes IL-22 Production via NF-?B. J Immunol. 2017 10 01; 199(7):2333-2342.
    View in: PubMed
    Score: 0.038
  38. FGFR and PTEN signaling interact during lens development to regulate cell survival. Dev Biol. 2016 Feb 15; 410(2):150-163.
    View in: PubMed
    Score: 0.034
  39. Loss of fibroblast HIF-1a accelerates tumorigenesis. Cancer Res. 2012 Jul 01; 72(13):3187-95.
    View in: PubMed
    Score: 0.026
  40. e-Science, caGrid, and Translational Biomedical Research. Computer (Long Beach Calif). 2008 Nov; 41(11):58-66.
    View in: PubMed
    Score: 0.020
  41. CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells. PLoS Genet. 2007 Sep; 3(9):1757-69.
    View in: PubMed
    Score: 0.019
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.