Louis Luttrell to Animals
This is a "connection" page, showing publications Louis Luttrell has written about Animals.
Connection Strength
1.379
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Transcriptomic characterization of signaling pathways associated with osteoblastic differentiation of MC-3T3E1 cells. PLoS One. 2019; 14(1):e0204197.
Score: 0.048
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The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling. Pharmacol Rev. 2017 07; 69(3):256-297.
Score: 0.043
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Translating in vitro ligand bias into in vivo efficacy. Cell Signal. 2018 01; 41:46-55.
Score: 0.042
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The conformational signature of ?-arrestin2 predicts its trafficking and signalling functions. Nature. 2016 Mar 31; 531(7596):665-8.
Score: 0.039
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Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism. Mol Pharmacol. 2015 Sep; 88(3):579-88.
Score: 0.037
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Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation. Methods. 2016 Jan 01; 92:51-63.
Score: 0.037
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Delineation of a conserved arrestin-biased signaling repertoire in vivo. Mol Pharmacol. 2015 Apr; 87(4):706-17.
Score: 0.036
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Arrestin-dependent angiotensin AT1 receptor signaling regulates Akt and mTor-mediated protein synthesis. J Biol Chem. 2014 Sep 19; 289(38):26155-26166.
Score: 0.035
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Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery. Mol Endocrinol. 2014 Mar; 28(3):281-94.
Score: 0.034
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Emergent biological properties of arrestin pathway-selective biased agonism. J Recept Signal Transduct Res. 2013 Jun; 33(3):153-61.
Score: 0.032
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Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity. Methods Enzymol. 2013; 522:229-62.
Score: 0.031
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Arrestin pathways as drug targets. Prog Mol Biol Transl Sci. 2013; 118:469-97.
Score: 0.031
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'Biasing' the parathyroid hormone receptor: a novel anabolic approach to increasing bone mass? Br J Pharmacol. 2011 Sep; 164(1):59-67.
Score: 0.029
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Refining efficacy: allosterism and bias in G protein-coupled receptor signaling. Methods Mol Biol. 2011; 756:3-35.
Score: 0.027
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Refining efficacy: exploiting functional selectivity for drug discovery. Adv Pharmacol. 2011; 62:79-107.
Score: 0.027
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A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation. Sci Transl Med. 2009 Oct 07; 1(1):1ra1.
Score: 0.025
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Diversity in arrestin function. Cell Mol Life Sci. 2009 Sep; 66(18):2953-73.
Score: 0.025
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Insulin-like growth factor-2/mannose-6 phosphate receptors. Vitam Horm. 2009; 80:667-97.
Score: 0.024
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The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth. Biochemistry. 2008 Nov 04; 47(44):11682-92.
Score: 0.023
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Heptahelical terpsichory. Who calls the tune? J Recept Signal Transduct Res. 2008; 28(1-2):39-58.
Score: 0.022
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Role of beta-arrestin-mediated desensitization and signaling in the control of angiotensin AT1a receptor-stimulated transcription. J Biol Chem. 2008 Jan 25; 283(4):2088-97.
Score: 0.022
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G protein-coupled receptor signaling complexity in neuronal tissue: implications for novel therapeutics. Curr Alzheimer Res. 2007 Feb; 4(1):3-19.
Score: 0.021
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Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors. J Biol Chem. 2006 Oct 20; 281(42):31399-407.
Score: 0.020
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Signal switching, crosstalk, and arrestin scaffolds: novel G protein-coupled receptor signaling in cardiovascular disease. Hypertension. 2006 Aug; 48(2):173-9.
Score: 0.020
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Transmembrane signaling by G protein-coupled receptors. Methods Mol Biol. 2006; 332:3-49.
Score: 0.019
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beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts. J Biol Chem. 2005 Sep 16; 280(37):32157-67.
Score: 0.019
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The origins of diversity and specificity in g protein-coupled receptor signaling. J Pharmacol Exp Ther. 2005 Aug; 314(2):485-94.
Score: 0.018
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Composition and function of g protein-coupled receptor signalsomes controlling mitogen-activated protein kinase activity. J Mol Neurosci. 2005; 26(2-3):253-64.
Score: 0.018
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Not so strange bedfellows: G-protein-coupled receptors and Src family kinases. Oncogene. 2004 Oct 18; 23(48):7969-78.
Score: 0.018
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Ectodomain shedding-dependent transactivation of epidermal growth factor receptors in response to insulin-like growth factor type I. Mol Endocrinol. 2004 Nov; 18(11):2727-39.
Score: 0.017
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Transactivation of the epidermal growth factor receptor mediates parathyroid hormone and prostaglandin F2 alpha-stimulated mitogen-activated protein kinase activation in cultured transgenic murine osteoblasts. Mol Endocrinol. 2003 Aug; 17(8):1607-21.
Score: 0.016
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'Location, location, location': activation and targeting of MAP kinases by G protein-coupled receptors. J Mol Endocrinol. 2003 Apr; 30(2):117-26.
Score: 0.016
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The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation. J Biol Chem. 2003 Feb 21; 278(8):6258-67.
Score: 0.016
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Big G, little G: G proteins and actin cytoskeletal reorganization. Mol Cell. 2002 Jun; 9(6):1152-4.
Score: 0.015
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Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus. J Biol Chem. 2002 Aug 09; 277(32):28631-40.
Score: 0.015
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The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. J Cell Sci. 2002 Feb 01; 115(Pt 3):455-65.
Score: 0.015
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beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation. J Biol Chem. 2002 Mar 15; 277(11):9429-36.
Score: 0.015
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Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2449-54.
Score: 0.014
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Transactivation of the EGF receptor mediates IGF-1-stimulated shc phosphorylation and ERK1/2 activation in COS-7 cells. J Biol Chem. 2000 Jul 21; 275(29):22583-9.
Score: 0.013
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?-Arrestin2 is a critical component of the GPCR-eNOS signalosome. Proc Natl Acad Sci U S A. 2020 05 26; 117(21):11483-11492.
Score: 0.013
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The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor. J Biol Chem. 2000 Mar 31; 275(13):9572-80.
Score: 0.013
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Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases. J Biol Chem. 1999 May 14; 274(20):13978-84.
Score: 0.012
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Regulation of tyrosine kinase cascades by G-protein-coupled receptors. Curr Opin Cell Biol. 1999 Apr; 11(2):177-83.
Score: 0.012
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GIT2-A keystone in ageing and age-related disease. Ageing Res Rev. 2018 May; 43:46-63.
Score: 0.011
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Regulation of mitogen-activated protein kinase pathways by catecholamine receptors. Adv Pharmacol. 1998; 42:466-70.
Score: 0.011
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G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases. J Biol Chem. 1997 Dec 12; 272(50):31648-56.
Score: 0.011
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Regulator of G protein signaling 2 is a key regulator of pancreatic ?-cell mass and function. Cell Death Dis. 2017 05 25; 8(5):e2821.
Score: 0.011
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Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation. J Biol Chem. 1997 Feb 14; 272(7):4637-44.
Score: 0.010
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S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization. J Lipid Res. 2017 02; 58(2):325-338.
Score: 0.010
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Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases. J Biol Chem. 1996 Aug 09; 271(32):19443-50.
Score: 0.010
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Angiotensin II receptors and peritoneal dialysis-induced peritoneal fibrosis. Int J Biochem Cell Biol. 2016 08; 77(Pt B):240-50.
Score: 0.010
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G beta gamma subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor. J Biol Chem. 1995 Jul 14; 270(28):16495-8.
Score: 0.009
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Exploring G protein-coupled receptor signaling networks using SILAC-based phosphoproteomics. Methods. 2016 Jan 01; 92:36-50.
Score: 0.009
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Effect of cellular expression of pleckstrin homology domains on Gi-coupled receptor signaling. J Biol Chem. 1995 Jun 02; 270(22):12984-9.
Score: 0.009
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Inhibition of Sphingosine Kinase 1 Ameliorates Angiotensin II-Induced Hypertension and Inhibits Transmembrane Calcium Entry via Store-Operated Calcium Channel. Mol Endocrinol. 2015 Jun; 29(6):896-908.
Score: 0.009
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Novel mechanism of plasma prekallikrein (PK) activation by vascular smooth muscle cells: evidence of the presence of PK activator. J Biol Regul Homeost Agents. 2014 Oct-Dec; 28(4):587-603.
Score: 0.009
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Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na+/H+ exchanger. Am J Physiol Cell Physiol. 2014 Sep 15; 307(6):C554-60.
Score: 0.009
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The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers. J Biol Chem. 2013 Jun 28; 288(26):18872-84.
Score: 0.008
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Textrous!: extracting semantic textual meaning from gene sets. PLoS One. 2013; 8(4):e62665.
Score: 0.008
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Angiotensin II activates NF-?B through AT1A receptor recruitment of ?-arrestin in cultured rat vascular smooth muscle cells. Am J Physiol Cell Physiol. 2013 Jun 15; 304(12):C1176-86.
Score: 0.008
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?-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivo. Mol Endocrinol. 2013 Feb; 27(2):296-314.
Score: 0.008
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Low-density lipoprotein induced expression of connective tissue growth factor via transactivation of sphingosine 1-phosphate receptors in mesangial cells. Mol Endocrinol. 2012 May; 26(5):833-45.
Score: 0.007
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Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation. Mol Immunol. 2011 Oct; 49(1-2):64-74.
Score: 0.007
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A pertussis toxin-sensitive G-protein mediates some aspects of insulin action in BC3H-1 murine myocytes. J Biol Chem. 1990 Oct 05; 265(28):16873-9.
Score: 0.007
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Plasma kallikrein promotes epidermal growth factor receptor transactivation and signaling in vascular smooth muscle through direct activation of protease-activated receptors. J Biol Chem. 2010 Nov 05; 285(45):35206-15.
Score: 0.007
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Novel mechanisms in the regulation of G protein-coupled receptor trafficking to the plasma membrane. J Biol Chem. 2010 Oct 29; 285(44):33816-25.
Score: 0.007
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Bradykinin decreases podocyte permeability through ADAM17-dependent epidermal growth factor receptor activation and zonula occludens-1 rearrangement. J Pharmacol Exp Ther. 2010 Sep 01; 334(3):775-83.
Score: 0.007
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HDL3, but not HDL2, stimulates plasminogen activator inhibitor-1 release from adipocytes: the role of sphingosine-1-phosphate. J Lipid Res. 2010 Sep; 51(9):2619-28.
Score: 0.007
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Beta-arrestin 2 negatively regulates sepsis-induced inflammation. Immunology. 2010 Jul; 130(3):344-51.
Score: 0.007
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Allosteric modulators of g protein-coupled receptors: future therapeutics for complex physiological disorders. J Pharmacol Exp Ther. 2009 Nov; 331(2):340-8.
Score: 0.006
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Angiotensin II-induced cyclooxygenase 2 expression in rat aorta vascular smooth muscle cells does not require heterotrimeric G protein activation. J Pharmacol Exp Ther. 2009 Jul; 330(1):118-24.
Score: 0.006
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Insulin and phorbol ester induce distinct phosphorylations of pp60c-src in the BC3H-1 murine myocyte cell line. Oncogene. 1989 Mar; 4(3):317-24.
Score: 0.006
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c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway. Cell Signal. 2009 Jan; 21(1):103-10.
Score: 0.006
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Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation. J Biol Chem. 2007 Oct 05; 282(40):29549-62.
Score: 0.005
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Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression. Mol Immunol. 2007 May; 44(12):3092-9.
Score: 0.005
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Hexose-independent activation of glycogen synthase and pyruvate dehydrogenase by insulin is dissociated in the mouse BC3H-1 cell line. Mol Pharmacol. 1986 Dec; 30(6):624-30.
Score: 0.005
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5-HT2A receptor induces ERK phosphorylation and proliferation through ADAM-17 tumor necrosis factor-alpha-converting enzyme (TACE) activation and heparin-bound epidermal growth factor-like growth factor (HB-EGF) shedding in mesangial cells. J Biol Chem. 2006 Jul 28; 281(30):21004-21012.
Score: 0.005
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Arrestin-mediated ERK activation by gonadotropin-releasing hormone receptors: receptor-specific activation mechanisms and compartmentalization. J Biol Chem. 2006 Feb 03; 281(5):2701-10.
Score: 0.005
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Beta-arrestin- and G protein receptor kinase-mediated calcium-sensing receptor desensitization. Mol Endocrinol. 2005 Apr; 19(4):1078-87.
Score: 0.005
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Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: a functional role for receptor-receptor interaction in vivo. Circulation. 2003 Sep 30; 108(13):1611-8.
Score: 0.004
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Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2. Proc Natl Acad Sci U S A. 2003 Sep 16; 100(19):10782-7.
Score: 0.004
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Protein kinase A and G protein-coupled receptor kinase phosphorylation mediates beta-1 adrenergic receptor endocytosis through different pathways. J Biol Chem. 2003 Sep 12; 278(37):35403-11.
Score: 0.004
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Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor. J Biol Chem. 2002 Jul 19; 277(29):26642-51.
Score: 0.004
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beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport. J Biol Chem. 2001 Nov 23; 276(47):43663-7.
Score: 0.004
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G protein-coupled receptors desensitize and down-regulate epidermal growth factor receptors in renal mesangial cells. J Biol Chem. 2001 Jul 20; 276(29):27335-44.
Score: 0.004
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Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding. J Biol Chem. 2001 Jun 22; 276(25):23155-60.
Score: 0.003
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Direct binding of activated c-Src to the beta 3-adrenergic receptor is required for MAP kinase activation. J Biol Chem. 2000 Dec 08; 275(49):38131-4.
Score: 0.003
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Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activity. Mol Cell Biol. 2000 Nov; 20(22):8352-63.
Score: 0.003
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Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors. Proc Natl Acad Sci U S A. 2000 Feb 15; 97(4):1489-94.
Score: 0.003
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The beta3-adrenergic receptor activates mitogen-activated protein kinase in adipocytes through a Gi-dependent mechanism. J Biol Chem. 1999 Apr 23; 274(17):12017-22.
Score: 0.003
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Serotonin 5-HT1A receptor-mediated Erk activation requires calcium/calmodulin-dependent receptor endocytosis. J Biol Chem. 1999 Feb 19; 274(8):4749-53.
Score: 0.003
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Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science. 1999 Jan 29; 283(5402):655-61.
Score: 0.003
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Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science. 1998 Apr 24; 280(5363):574-7.
Score: 0.003
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Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase. J Biol Chem. 1997 Aug 01; 272(31):19125-32.
Score: 0.003
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G-protein-coupled receptors and their regulation: activation of the MAP kinase signaling pathway by G-protein-coupled receptors. Adv Second Messenger Phosphoprotein Res. 1997; 31:263-77.
Score: 0.003
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Mitogenic signaling via G protein-coupled receptors. Endocr Rev. 1996 Dec; 17(6):698-714.
Score: 0.003
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Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway. J Biol Chem. 1996 May 24; 271(21):12133-6.
Score: 0.002
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G(o)-protein alpha-subunits activate mitogen-activated protein kinase via a novel protein kinase C-dependent mechanism. J Biol Chem. 1996 Jan 19; 271(3):1266-9.
Score: 0.002
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Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation. J Biol Chem. 1995 Jul 21; 270(29):17148-53.
Score: 0.002
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Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor. J Biol Chem. 1994 Jun 03; 269(22):15776-85.
Score: 0.002
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Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase. Proc Natl Acad Sci U S A. 1994 Apr 26; 91(9):3637-41.
Score: 0.002
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Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling. J Biol Chem. 1994 Feb 25; 269(8):6193-7.
Score: 0.002
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Phosphatidylinositol-glycan anchors of membrane proteins: potential precursors of insulin mediators. Science. 1988 Apr 22; 240(4851):509-11.
Score: 0.001
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Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src. Mol Cell Biol. 1988 Jan; 8(1):497-501.
Score: 0.001