Yusuf Hannun to Phosphorylation
This is a "connection" page, showing publications Yusuf Hannun has written about Phosphorylation.
Connection Strength
1.738
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Ceramide launches an acute anti-adhesion pro-migration cell signaling program in response to chemotherapy. FASEB J. 2020 06; 34(6):7610-7630.
Score: 0.136
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Co-ordinated activation of classical and novel PKC isoforms is required for PMA-induced mTORC1 activation. PLoS One. 2017; 12(9):e0184818.
Score: 0.114
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Sustained activation of protein kinase C induces delayed phosphorylation and regulates the fate of epidermal growth factor receptor. PLoS One. 2013; 8(11):e80721.
Score: 0.087
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Identification and characterization of protein phosphatase 2C activation by ceramide. J Lipid Res. 2012 Aug; 53(8):1513-21.
Score: 0.079
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Protein phosphatase 1a mediates ceramide-induced ERM protein dephosphorylation: a novel mechanism independent of phosphatidylinositol 4, 5-biphosphate (PIP2) and myosin/ERM phosphatase. J Biol Chem. 2012 Mar 23; 287(13):10145-10155.
Score: 0.077
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Neutral sphingomyelinase-2 mediates growth arrest by retinoic acid through modulation of ribosomal S6 kinase. J Biol Chem. 2011 Jun 17; 286(24):21565-76.
Score: 0.073
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Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation: probing sphingolipid signaling at the outer plasma membrane. J Biol Chem. 2010 Oct 15; 285(42):32476-85.
Score: 0.069
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Downregulation of neutral ceramidase by gemcitabine: Implications for cell cycle regulation. Biochim Biophys Acta. 2009 Aug; 1791(8):730-9.
Score: 0.063
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Acid beta-glucosidase 1 counteracts p38delta-dependent induction of interleukin-6: possible role for ceramide as an anti-inflammatory lipid. J Biol Chem. 2009 May 08; 284(19):12979-88.
Score: 0.063
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Hydroxyurea sensitivity reveals a role for ISC1 in the regulation of G2/M. J Biol Chem. 2009 Mar 27; 284(13):8241-6.
Score: 0.062
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A novel role for protein kinase Cdelta-mediated phosphorylation of acid sphingomyelinase in UV light-induced mitochondrial injury. FASEB J. 2008 Jan; 22(1):183-93.
Score: 0.057
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Mechanism of inhibition of sequestration of protein kinase C alpha/betaII by ceramide. Roles of ceramide-activated protein phosphatases and phosphorylation/dephosphorylation of protein kinase C alpha/betaII on threonine 638/641. J Biol Chem. 2007 Jul 13; 282(28):20647-56.
Score: 0.056
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Activation of acid sphingomyelinase by protein kinase Cdelta-mediated phosphorylation. J Biol Chem. 2007 Apr 13; 282(15):11549-61.
Score: 0.055
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Role for neutral sphingomyelinase-2 in tumor necrosis factor alpha-stimulated expression of vascular cell adhesion molecule-1 (VCAM) and intercellular adhesion molecule-1 (ICAM) in lung epithelial cells: p38 MAPK is an upstream regulator of nSMase2. J Biol Chem. 2007 Jan 12; 282(2):1384-96.
Score: 0.054
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Protein kinase C-induced activation of a ceramide/protein phosphatase 1 pathway leading to dephosphorylation of p38 MAPK. J Biol Chem. 2006 Dec 01; 281(48):36793-802.
Score: 0.053
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Ceramide kinase regulates TNF-a-induced immune responses in human monocytic cells. Sci Rep. 2021 04 15; 11(1):8259.
Score: 0.036
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Regulation of receptor-mediated protein kinase C membrane trafficking by autophosphorylation. J Biol Chem. 2000 Jun 02; 275(22):17024-34.
Score: 0.034
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An essential role for autophosphorylation in the dissociation of activated protein kinase C from the plasma membrane. J Biol Chem. 1998 Oct 09; 273(41):26870-4.
Score: 0.031
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Protein kinase C beta II specifically binds to and is activated by F-actin. J Biol Chem. 1996 Jun 28; 271(26):15823-30.
Score: 0.026
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Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion. FASEB J. 2015 Nov; 29(11):4654-69.
Score: 0.025
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Ceramide: an endogenous regulator of apoptosis and growth suppression. Immunol Today. 1995 Jun; 16(6):294-7.
Score: 0.024
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A novel role of sphingosine kinase-1 in the invasion and angiogenesis of VHL mutant clear cell renal cell carcinoma. FASEB J. 2015 Jul; 29(7):2803-13.
Score: 0.024
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Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1347-51.
Score: 0.024
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Stereoselectivity of induction of the retinoblastoma gene product (pRb) dephosphorylation by D-erythro-sphingosine supports a role for pRb in growth suppression by sphingosine. Biochemistry. 1995 Feb 14; 34(6):1885-92.
Score: 0.024
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Sphingosine kinase 1 regulates tumor necrosis factor-mediated RANTES induction through p38 mitogen-activated protein kinase but independently of nuclear factor ?B activation. J Biol Chem. 2013 Sep 20; 288(38):27667-27679.
Score: 0.021
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Epidermal growth factor-induced cellular invasion requires sphingosine-1-phosphate/sphingosine-1-phosphate 2 receptor-mediated ezrin activation. FASEB J. 2013 Aug; 27(8):3155-66.
Score: 0.021
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Sphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteins. Biochem J. 2013 Feb 01; 449(3):661-72.
Score: 0.021
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Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKC alpha. J Biol Chem. 1993 Jan 05; 268(1):658-64.
Score: 0.021
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Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine. J Biol Chem. 1992 Nov 25; 267(33):23459-62.
Score: 0.020
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Sphingosine activation of protein kinases in Jurkat T cells. In vitro phosphorylation of endogenous protein substrates and specificity of action. J Biol Chem. 1992 Jul 25; 267(21):15246-51.
Score: 0.020
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Oncogenic K-Ras regulates bioactive sphingolipids in a sphingosine kinase 1-dependent manner. J Biol Chem. 2012 Sep 14; 287(38):31794-803.
Score: 0.020
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Ceramide stimulates a cytosolic protein phosphatase. J Biol Chem. 1992 Mar 15; 267(8):5048-51.
Score: 0.019
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Activation of protein kinase C by oleic acid. Determination and analysis of inhibition by detergent micelles and physiologic membranes: requirement for free oleate. J Biol Chem. 1992 Feb 25; 267(6):3605-12.
Score: 0.019
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Arachidonic and cis-unsaturated fatty acids induce selective platelet substrate phosphorylation through activation of cytosolic protein kinase C. FEBS Lett. 1991 Nov 04; 292(1-2):98-102.
Score: 0.019
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Use of D-erythro-sphingosine as a pharmacological inhibitor of protein kinase C in human platelets. Biochem J. 1991 Sep 01; 278 ( Pt 2):387-92.
Score: 0.019
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Delayed accumulation of diacylglycerol in platelets as a mechanism for regulation of onset of aggregation and secretion. Blood. 1991 Jul 15; 78(2):435-44.
Score: 0.019
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Isofagomine in vivo effects in a neuronopathic Gaucher disease mouse. PLoS One. 2011 Apr 20; 6(4):e19037.
Score: 0.018
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Regulation of platelet protein kinase C by oleic acid. Kinetic analysis of allosteric regulation and effects on autophosphorylation, phorbol ester binding, and susceptibility to inhibition. J Biol Chem. 1990 Sep 25; 265(27):16437-43.
Score: 0.018
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Rat brain protein kinase C. Kinetic analysis of substrate dependence, allosteric regulation, and autophosphorylation. J Biol Chem. 1990 Feb 15; 265(5):2962-72.
Score: 0.017
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Involvement of sphingoid bases in mediating reactive oxygen intermediate production and programmed cell death in Arabidopsis. Cell Res. 2007 Dec; 17(12):1030-40.
Score: 0.014
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Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells. J Biol Chem. 2007 Jun 08; 282(23):16718-28.
Score: 0.014
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Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids. J Biol Chem. 2006 Mar 17; 281(11):7324-31.
Score: 0.013
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Sphingosine kinase 1 (SPHK1) is induced by transforming growth factor-beta and mediates TIMP-1 up-regulation. J Biol Chem. 2004 Dec 24; 279(52):53994-4001.
Score: 0.012
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Modulation of transforming growth factor-beta (TGF-beta) signaling by endogenous sphingolipid mediators. J Biol Chem. 2003 Mar 14; 278(11):9276-82.
Score: 0.010
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Proteolytic cleavage of phospholipase C-gamma1 during apoptosis in Molt-4 cells. FASEB J. 2000 Jun; 14(9):1083-92.
Score: 0.009
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Phorbol myristate acetate-dependent association of protein kinase C alpha with phospholipase D1 in intact cells. Biochim Biophys Acta. 1997 Aug 16; 1347(2-3):199-204.
Score: 0.007
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Phosphorylation specificities of protein kinase C isozymes for bovine cardiac troponin I and troponin T and sites within these proteins and regulation of myofilament properties. J Biol Chem. 1996 Sep 20; 271(38):23277-83.
Score: 0.007
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Ceramide inactivates cellular protein kinase Calpha. J Biol Chem. 1996 May 31; 271(22):13169-74.
Score: 0.007
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15-Hydroxyeicosatetraenoic acid-mediated potentiation of thrombin-induced platelet functions occurs via enhanced production of phosphoinositide-derived second messengers--sn-1,2-diacylglycerol and inositol-1,4,5-trisphosphate. Blood. 1992 Dec 01; 80(11):2765-73.
Score: 0.005
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Regulation of the epidermal growth factor receptor phosphorylation state by sphingosine in A431 human epidermoid carcinoma cells. J Biol Chem. 1988 Apr 15; 263(11):5319-27.
Score: 0.004