Connection

Lee Chao to Kallikreins

This is a "connection" page, showing publications Lee Chao has written about Kallikreins.
Connection Strength

5.568
  1. Kallikrein gene delivery improves serum glucose and lipid profiles and cardiac function in streptozotocin-induced diabetic rats. Diabetes. 2005 May; 54(5):1573-80.
    View in: PubMed
    Score: 0.222
  2. Novel roles of kallistatin, a specific tissue kallikrein inhibitor, in vascular remodeling. Biol Chem. 2001 Jan; 382(1):15-21.
    View in: PubMed
    Score: 0.164
  3. Adenovirus-mediated kallikrein gene delivery reverses salt-induced renal injury in Dahl salt-sensitive rats. Kidney Int. 1998 Oct; 54(4):1250-60.
    View in: PubMed
    Score: 0.140
  4. Human kallikrein gene delivery attenuates hypertension, cardiac hypertrophy, and renal injury in Dahl salt-sensitive rats. Hum Gene Ther. 1998 Jan 01; 9(1):21-31.
    View in: PubMed
    Score: 0.133
  5. New experimental evidence for a role of tissue kallikrein in hypertension. Nephrol Dial Transplant. 1997 Aug; 12(8):1569-74.
    View in: PubMed
    Score: 0.129
  6. DNA polymorphisms in the 5'-flanking region of the human tissue kallikrein gene. Hum Genet. 1997 Jun; 99(6):727-34.
    View in: PubMed
    Score: 0.128
  7. Kallikrein gene therapy: a new strategy for hypertensive diseases. Immunopharmacology. 1997 Jun; 36(2-3):229-36.
    View in: PubMed
    Score: 0.128
  8. Kallikrein gene therapy in newborn and adult hypertensive rats. Can J Physiol Pharmacol. 1997 Jun; 75(6):750-6.
    View in: PubMed
    Score: 0.128
  9. Experimental kallikrein gene therapy in hypertension, cardiovascular and renal diseases. Pharmacol Res. 1997 Jun; 35(6):517-22.
    View in: PubMed
    Score: 0.128
  10. High level of circulating human tissue kallikrein induces hypotension in a transgenic mouse model. Clin Exp Hypertens. 1996 Nov; 18(8):975-93.
    View in: PubMed
    Score: 0.123
  11. Identification and characterization of two promoters of rat kallikrein-binding protein gene. Biochim Biophys Acta. 1996 Jul 17; 1307(3):285-93.
    View in: PubMed
    Score: 0.120
  12. Kallistatin, a novel human tissue kallikrein inhibitor: levels in body fluids, blood cells, and tissues in health and disease. J Lab Clin Med. 1996 Jun; 127(6):612-20.
    View in: PubMed
    Score: 0.119
  13. Systemic and portal vein delivery of human kallikrein gene reduces blood pressure in hypertensive rats. Hum Gene Ther. 1996 May 20; 7(8):901-11.
    View in: PubMed
    Score: 0.119
  14. Tissue kallikrein inhibitors in mammals. Immunopharmacology. 1996 May; 32(1-3):67-72.
    View in: PubMed
    Score: 0.119
  15. High level expression of human tissue kallikrein in the circulation induces hypotension in transgenic mice. Immunopharmacology. 1996 May; 32(1-3):105-7.
    View in: PubMed
    Score: 0.119
  16. Functional analysis of human tissue kallikrein in transgenic mouse models. Hypertension. 1996 Mar; 27(3 Pt 2):491-4.
    View in: PubMed
    Score: 0.117
  17. Muscle delivery of human kallikrein gene reduces blood pressure in hypertensive rats. Hypertension. 1995 Apr; 25(4 Pt 2):715-9.
    View in: PubMed
    Score: 0.110
  18. Intramuscular delivery of rat kallikrein-binding protein gene reverses hypotension in transgenic mice expressing human tissue kallikrein. J Biol Chem. 1995 Jan 06; 270(1):451-5.
    View in: PubMed
    Score: 0.108
  19. Histopathology of lymphatic tissues in transgenic mice expressing human tissue kallikrein gene. Lab Invest. 1994 Nov; 71(5):680-7.
    View in: PubMed
    Score: 0.107
  20. Human tissue kallikrein induces hypotension in transgenic mice. Hypertension. 1994 Feb; 23(2):236-43.
    View in: PubMed
    Score: 0.102
  21. Molecular cloning and characterization of rKlk10, a cDNA encoding T-kininogenase from rat submandibular gland and kidney. Biochemistry. 1992 Nov 10; 31(44):10922-8.
    View in: PubMed
    Score: 0.093
  22. Specificity determinants of rat tissue kallikrein probed by site-directed mutagenesis. Protein Eng. 1992 Sep; 5(6):569-75.
    View in: PubMed
    Score: 0.092
  23. Comparative studies on P2 specificity of wild-type rat tissue kallikrein, Y99H:W215G mutant and tonin. Agents Actions Suppl. 1992; 38 ( Pt 1):59-65.
    View in: PubMed
    Score: 0.088
  24. Localization of kallikrein gene family proteases in rat tissues. Agents Actions Suppl. 1992; 38 ( Pt 1):595-602.
    View in: PubMed
    Score: 0.088
  25. Expression of kallikrein-binding protein and alpha 1-antitrypsin genes in response to sex hormones, growth, inflammation and hypertension. Agents Actions Suppl. 1992; 38 ( Pt 1):174-81.
    View in: PubMed
    Score: 0.088
  26. Evolution of the kallikrein gene family. Agents Actions Suppl. 1992; 38 ( Pt 1):26-33.
    View in: PubMed
    Score: 0.088
  27. Purification and characterization of recombinant tissue kallikrein from Escherichia coli and yeast. Biochem J. 1991 May 15; 276 ( Pt 1):63-71.
    View in: PubMed
    Score: 0.084
  28. Tissue kallikrein-binding protein is a serpin. I. Purification, characterization, and distribution in normotensive and spontaneously hypertensive rats. J Biol Chem. 1990 Sep 25; 265(27):16394-401.
    View in: PubMed
    Score: 0.081
  29. Kallikrein multigene families and the regulation of their expression. J Cardiovasc Pharmacol. 1990; 15 Suppl 6:S7-16.
    View in: PubMed
    Score: 0.077
  30. Restriction fragment length polymorphisms mapped in spontaneously hypertensive rats using kallikrein probes. J Hypertens. 1989 Nov; 7(11):865-71.
    View in: PubMed
    Score: 0.076
  31. Characterization of genes encoding rat tonin and a kallikrein-like serine protease. Biochemistry. 1989 Jun 27; 28(13):5334-43.
    View in: PubMed
    Score: 0.074
  32. Structural analysis of a rat renal kallikrein gene. Adv Exp Med Biol. 1989; 247A:73-80.
    View in: PubMed
    Score: 0.071
  33. Sex dimorphism and estrogen regulation of kininogens in rat serum, adrenal gland and kidney. Adv Exp Med Biol. 1989; 247B:297-303.
    View in: PubMed
    Score: 0.071
  34. Molecular cloning and characterization of two rat renal kallikrein genes. Biochemistry. 1988 Sep 20; 27(19):7189-96.
    View in: PubMed
    Score: 0.070
  35. A major difference of kallikrein-binding protein in spontaneously hypertensive versus normotensive rats. J Hypertens. 1988 Jul; 6(7):551-7.
    View in: PubMed
    Score: 0.069
  36. Circulating autoantibodies to mammalian tissue kallikreins. Proc Soc Exp Biol Med. 1988 Mar; 187(3):320-6.
    View in: PubMed
    Score: 0.067
  37. Identification of latent tissue kallikrein, prolactin and growth hormone secretion in GH3 pituitary cells using modified radioimmunoassays. Mol Cell Endocrinol. 1988 Jan; 55(1):21-31.
    View in: PubMed
    Score: 0.067
  38. Identification and expression of kallikrein gene family in rat submandibular and prostate glands using monoclonal antibodies as specific probes. Biochim Biophys Acta. 1987 Dec 08; 910(3):233-9.
    View in: PubMed
    Score: 0.066
  39. Nitric oxide mediates cardiac protection of tissue kallikrein by reducing inflammation and ventricular remodeling after myocardial ischemia/reperfusion. Life Sci. 2008 Jan 16; 82(3-4):156-65.
    View in: PubMed
    Score: 0.066
  40. Kallikrein protects against ischemic stroke by inhibiting apoptosis and inflammation and promoting angiogenesis and neurogenesis. Hum Gene Ther. 2006 Feb; 17(2):206-19.
    View in: PubMed
    Score: 0.058
  41. Kallikrein gene transfer reduces renal fibrosis, hypertrophy, and proliferation in DOCA-salt hypertensive rats. Am J Physiol Renal Physiol. 2005 Sep; 289(3):F622-31.
    View in: PubMed
    Score: 0.055
  42. Prophylactic adenovirus-mediated human kallistatin gene therapy suppresses rat arthritis by inhibiting angiogenesis and inflammation. Arthritis Rheum. 2005 Apr; 52(4):1319-24.
    View in: PubMed
    Score: 0.055
  43. Kallikrein/kinin protects against myocardial apoptosis after ischemia/reperfusion via Akt-glycogen synthase kinase-3 and Akt-Bad.14-3-3 signaling pathways. J Biol Chem. 2005 Mar 04; 280(9):8022-30.
    View in: PubMed
    Score: 0.054
  44. Kallikrein gene transfer protects against ischemic stroke by promoting glial cell migration and inhibiting apoptosis. Hypertension. 2004 Feb; 43(2):452-9.
    View in: PubMed
    Score: 0.050
  45. Kallikrein gene delivery attenuates cardiac remodeling and promotes neovascularization in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol. 2003 Oct; 285(4):H1479-88.
    View in: PubMed
    Score: 0.049
  46. Kallikrein gene delivery attenuates myocardial infarction and apoptosis after myocardial ischemia and reperfusion. Hypertension. 2000 Jan; 35(1 Pt 1):25-31.
    View in: PubMed
    Score: 0.038
  47. Adenovirus-mediated kallikrein gene transfer inhibits neointima formation via increased production of nitric oxide in rat artery. Immunopharmacology. 1999 Oct 15; 44(1-2):137-43.
    View in: PubMed
    Score: 0.038
  48. Adenovirus-mediated kallikrein gene delivery reduces aortic thickening and stroke-induced death rate in Dahl salt-sensitive rats. Stroke. 1999 Sep; 30(9):1925-31; discussion 1931-2.
    View in: PubMed
    Score: 0.037
  49. Kallikrein gene delivery inhibits vascular smooth muscle cell growth and neointima formation in the rat artery after balloon angioplasty. Hypertension. 1999 Aug; 34(2):164-70.
    View in: PubMed
    Score: 0.037
  50. Potassium supplement upregulates the expression of renal kallikrein and bradykinin B2 receptor in SHR. Am J Physiol. 1999 03; 276(3):F476-84.
    View in: PubMed
    Score: 0.036
  51. Localization and expression of tissue kallikrein and kallistatin in human blood vessels. J Histochem Cytochem. 1999 Feb; 47(2):221-8.
    View in: PubMed
    Score: 0.036
  52. Cellular localization of kallistatin and tissue kallikrein in human pancreas and salivary glands. Histochem Cell Biol. 1998 Nov; 110(5):477-84.
    View in: PubMed
    Score: 0.035
  53. Human kallikrein gene delivery protects against gentamycin-induced nephrotoxicity in rats. Kidney Int. 1998 May; 53(5):1305-13.
    View in: PubMed
    Score: 0.034
  54. Kallikrein gene delivery attenuates hypertension and cardiac hypertrophy and enhances renal function in Goldblatt hypertensive rats. Hypertension. 1998 May; 31(5):1104-10.
    View in: PubMed
    Score: 0.034
  55. Central delivery of human tissue kallikrein gene reduces blood pressure in hypertensive rats. Biochem Biophys Res Commun. 1998 Mar 17; 244(2):449-54.
    View in: PubMed
    Score: 0.034
  56. Effect of cyclosporin A on the expression of tissue kallikrein, kininogen, and bradykinin receptor in rat. Am J Physiol. 1997 11; 273(5):F783-9.
    View in: PubMed
    Score: 0.033
  57. Gene therapy in hypertension: adenovirus-mediated kallikrein gene delivery in hypertensive rats. Hum Gene Ther. 1997 Oct 10; 8(15):1753-61.
    View in: PubMed
    Score: 0.033
  58. Molecular cloning and expression of rat kallistatin gene. Biochim Biophys Acta. 1997 Sep 12; 1353(3):277-86.
    View in: PubMed
    Score: 0.033
  59. Kallistatin is a potent new vasodilator. J Clin Invest. 1997 Jul 01; 100(1):11-7.
    View in: PubMed
    Score: 0.032
  60. Tissue-specific expression and promoter analyses of the human tissue kallikrein gene in transgenic mice. Biochem J. 1997 Jul 01; 325 ( Pt 1):111-6.
    View in: PubMed
    Score: 0.032
  61. Expression of human tissue kallikrein in rat salivary glands and its secretion into circulation following adenovirus-mediated gene transfer. Immunopharmacology. 1997 Jun; 36(2-3):221-7.
    View in: PubMed
    Score: 0.032
  62. Kallikrein-binding protein levels are reduced in the retinas of streptozotocin-induced diabetic rats. Invest Ophthalmol Vis Sci. 1997 Mar; 38(3):658-64.
    View in: PubMed
    Score: 0.031
  63. Adenovirus-mediated delivery of human kallistatin gene reduces blood pressure of spontaneously hypertensive rats. Hum Gene Ther. 1997 Feb 10; 8(3):341-7.
    View in: PubMed
    Score: 0.031
  64. Beneficial effects of kallikrein-binding protein in transgenic mice during endotoxic shock. Life Sci. 1997; 60(17):1431-5.
    View in: PubMed
    Score: 0.031
  65. High-salt diet upregulates kininogen and downregulates tissue kallikrein expression in Dahl-SS and SHR rats. Am J Physiol. 1996 Oct; 271(4 Pt 2):F824-30.
    View in: PubMed
    Score: 0.031
  66. Expression and cellular localization of tissue kallikrein-kinin system in human adrenal gland. Am J Physiol. 1996 Sep; 271(3 Pt 2):F709-16.
    View in: PubMed
    Score: 0.030
  67. Differential regulation of kallikrein, kininogen, and kallikrein-binding protein in arterial hypertensive rats. Am J Physiol. 1996 Jul; 271(1 Pt 2):F78-86.
    View in: PubMed
    Score: 0.030
  68. Regulatory elements in the promoter region of the renal kallikrein gene in normotensive vs hypertensive rats. Biochem Biophys Res Commun. 1995 Dec 05; 217(1):113-22.
    View in: PubMed
    Score: 0.029
  69. Cellular localization of tissue kallikrein and kallistatin mRNAs in human kidney. Kidney Int. 1995 Sep; 48(3):690-7.
    View in: PubMed
    Score: 0.028
  70. Molecular cloning, purification and in situ localization of human colon kallikrein. Biochem J. 1995 Apr 15; 307 ( Pt 2):481-6.
    View in: PubMed
    Score: 0.028
  71. Direct gene delivery of human tissue kallikrein reduces blood pressure in spontaneously hypertensive rats. J Clin Invest. 1995 Apr; 95(4):1710-6.
    View in: PubMed
    Score: 0.028
  72. Molecular cloning and characterization of a novel kallikrein transcript in colon and its distribution in human tissues. Braz J Med Biol Res. 1994 Aug; 27(8):1829-38.
    View in: PubMed
    Score: 0.026
  73. Expression and characterization of rat kallikrein-binding protein in Escherichia coli. Biochem J. 1993 Jun 15; 292 ( Pt 3):825-32.
    View in: PubMed
    Score: 0.024
  74. Kallistatin: a novel human tissue kallikrein inhibitor. Purification, characterization, and reactive center sequence. J Biol Chem. 1992 Dec 25; 267(36):25873-80.
    View in: PubMed
    Score: 0.024
  75. Biochemical characterization and substrate specificity of rat prostate kallikrein (S3): comparison with tissue kallikrein, tonin and T-kininogenase. Biochim Biophys Acta. 1992 Jun 24; 1121(3):309-16.
    View in: PubMed
    Score: 0.023
  76. In vivo catabolism of human kallikrein-binding protein and its complex with tissue kallikrein. J Lab Clin Med. 1992 May; 119(5):514-21.
    View in: PubMed
    Score: 0.022
  77. Effects of diabetes and insulin on expression of kallikrein and renin genes in the kidney. Kidney Int. 1992 Apr; 41(4):789-95.
    View in: PubMed
    Score: 0.022
  78. Molecular cloning and sequence analysis of the mouse kallikrein-binding protein gene. Biochim Biophys Acta. 1991 Dec 02; 1129(1):127-30.
    View in: PubMed
    Score: 0.022
  79. Kallistatin inhibits vascular inflammation by antagonizing tumor necrosis factor-alpha-induced nuclear factor kappaB activation. Hypertension. 2010 Aug; 56(2):260-7.
    View in: PubMed
    Score: 0.020
  80. Differential interactions of human kallikrein-binding protein and alpha 1-antitrypsin with human tissue kallikrein. Biochem J. 1990 Apr 01; 267(1):79-84.
    View in: PubMed
    Score: 0.019
  81. Sex dimorphism and inflammatory regulation of T-kininogen and T-kininogenase. Biochim Biophys Acta. 1989 Jun 27; 991(3):477-83.
    View in: PubMed
    Score: 0.018
  82. Renal kallikrein mRNA localization by in situ hybridization. Kidney Int. 1989 Jun; 35(6):1324-9.
    View in: PubMed
    Score: 0.018
  83. Human kallistatin, a new tissue kallikrein-binding protein: purification and characterization. Adv Exp Med Biol. 1989; 247B:1-8.
    View in: PubMed
    Score: 0.018
  84. Comparison of the distribution of tissue kallikrein and esterase A, a kallikrein-like enzyme, in rat kidney using specific monoclonal antibodies. J Histochem Cytochem. 1988 Oct; 36(10):1251-4.
    View in: PubMed
    Score: 0.018
  85. Upregulation of kallistatin expression in rheumatoid joints. J Rheumatol. 2007 Nov; 34(11):2171-6.
    View in: PubMed
    Score: 0.016
  86. Identification and characterization of a tissue kallikrein in rat skeletal muscles. Biochem J. 1987 May 01; 243(3):773-8.
    View in: PubMed
    Score: 0.016
  87. Structural elements of kallistatin required for inhibition of angiogenesis. Am J Physiol Cell Physiol. 2003 06; 284(6):C1604-13.
    View in: PubMed
    Score: 0.012
  88. Identification of a major heparin-binding site in kallistatin. J Biol Chem. 2001 Jan 12; 276(2):1276-84.
    View in: PubMed
    Score: 0.010
  89. Tissue kallikrein-binding protein reduces blood pressure in transgenic mice. J Biol Chem. 1996 Nov 01; 271(44):27590-4.
    View in: PubMed
    Score: 0.008
  90. Kallistatin in human ocular tissues: reduced levels in vitreous fluids from patients with diabetic retinopathy. Curr Eye Res. 1996 Nov; 15(11):1117-23.
    View in: PubMed
    Score: 0.008
  91. Expression and cellular localization of the kallikrein-kinin system in human ocular tissues. Exp Eye Res. 1996 Jul; 63(1):19-26.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.