Yusuf Hannun to Cell Line
This is a "connection" page, showing publications Yusuf Hannun has written about Cell Line.
Connection Strength
1.965
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Probing compartment-specific sphingolipids with targeted bacterial sphingomyelinases and ceramidases. J Lipid Res. 2019 11; 60(11):1841-1850.
Score: 0.121
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Activation of p38 Mitogen-Activated Protein Kinase in Gaucher's Disease. PLoS One. 2015; 10(8):e0136633.
Score: 0.093
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Sustained activation of protein kinase C induces delayed phosphorylation and regulates the fate of epidermal growth factor receptor. PLoS One. 2013; 8(11):e80721.
Score: 0.082
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Sustained PKC?II activity confers oncogenic properties in a phospholipase D- and mTOR-dependent manner. FASEB J. 2014 Jan; 28(1):495-505.
Score: 0.081
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Identification and characterization of protein phosphatase 2C activation by ceramide. J Lipid Res. 2012 Aug; 53(8):1513-21.
Score: 0.074
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Anterograde and retrograde transport of neutral sphingomyelinase-2 between the Golgi and the plasma membrane. Biochim Biophys Acta. 2010 Dec; 1801(12):1361-74.
Score: 0.065
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Identification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5. J Biol Chem. 2010 Jun 04; 285(23):17993-8002.
Score: 0.064
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Dihydroceramide desaturase activity is modulated by oxidative stress. Biochem J. 2010 Mar 29; 427(2):265-74.
Score: 0.064
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Sustained receptor stimulation leads to sequestration of recycling endosomes in a classical protein kinase C- and phospholipase D-dependent manner. J Biol Chem. 2009 Aug 14; 284(33):22322-22331.
Score: 0.060
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Downregulation of neutral ceramidase by gemcitabine: Implications for cell cycle regulation. Biochim Biophys Acta. 2009 Aug; 1791(8):730-9.
Score: 0.059
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Redox regulation of neutral sphingomyelinase-1 activity in HEK293 cells through a GSH-dependent mechanism. Arch Biochem Biophys. 2007 Mar 15; 459(2):295-300.
Score: 0.050
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Acid ceramidase but not acid sphingomyelinase is required for tumor necrosis factor-{alpha}-induced PGE2 production. J Biol Chem. 2006 Aug 25; 281(34):24695-703.
Score: 0.049
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Dynamic sequestration of the recycling compartment by classical protein kinase C. J Biol Chem. 2006 Aug 04; 281(31):22321-22331.
Score: 0.049
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Selective inhibition of juxtanuclear translocation of protein kinase C betaII by a negative feedback mechanism involving ceramide formed from the salvage pathway. J Biol Chem. 2005 Jan 28; 280(4):2606-12.
Score: 0.044
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Isoenzyme-specific translocation of protein kinase C (PKC)betaII and not PKCbetaI to a juxtanuclear subset of recycling endosomes: involvement of phospholipase D. J Biol Chem. 2004 Jul 02; 279(27):28251-6.
Score: 0.042
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cPKC-dependent sequestration of membrane-recycling components in a subset of recycling endosomes. J Biol Chem. 2003 Dec 26; 278(52):52747-54.
Score: 0.041
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The sphingosine kinase 1/sphingosine-1-phosphate pathway mediates COX-2 induction and PGE2 production in response to TNF-alpha. FASEB J. 2003 Aug; 17(11):1411-21.
Score: 0.040
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Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides. Cell Death Dis. 2021 01 04; 12(1):27.
Score: 0.034
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Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening. SLAS Discov. 2021 01; 26(1):113-121.
Score: 0.033
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Inhibition of acid ceramidase regulates MHC class II antigen presentation and suppression of autoimmune arthritis. Cytokine. 2020 11; 135:155219.
Score: 0.033
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Molecular cloning and characterization of a human mitochondrial ceramidase. J Biol Chem. 2000 Jul 14; 275(28):21508-13.
Score: 0.033
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Regulation of receptor-mediated protein kinase C membrane trafficking by autophosphorylation. J Biol Chem. 2000 Jun 02; 275(22):17024-34.
Score: 0.032
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Effects of sphingosine and other sphingolipids on protein kinase C. Methods Enzymol. 2000; 312:361-73.
Score: 0.031
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Function of the cloned putative neutral sphingomyelinase as lyso-platelet activating factor-phospholipase C. J Biol Chem. 1999 Dec 31; 274(53):38131-9.
Score: 0.031
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RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis. PLoS Genet. 2019 01; 15(1):e1007914.
Score: 0.029
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An essential role for autophosphorylation in the dissociation of activated protein kinase C from the plasma membrane. J Biol Chem. 1998 Oct 09; 273(41):26870-4.
Score: 0.029
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p53-dependent ceramide response to genotoxic stress. J Clin Invest. 1998 Jul 15; 102(2):329-39.
Score: 0.028
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Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C? J Biol Chem. 1998 Jun 05; 273(23):14550-9.
Score: 0.028
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Visualization of dynamic trafficking of a protein kinase C betaII/green fluorescent protein conjugate reveals differences in G protein-coupled receptor activation and desensitization. J Biol Chem. 1998 Apr 24; 273(17):10755-62.
Score: 0.028
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The Synergy between Palmitate and TNF-a for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation. J Immunol. 2018 05 15; 200(10):3599-3611.
Score: 0.028
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Bladder cancer cell growth and motility implicate cannabinoid 2 receptor-mediated modifications of sphingolipids metabolism. Sci Rep. 2017 02 13; 7:42157.
Score: 0.026
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Bcl-2 interrupts the ceramide-mediated pathway of cell death. Proc Natl Acad Sci U S A. 1996 May 28; 93(11):5325-8.
Score: 0.024
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Activation of a retinoblastoma-protein-dependent pathway by sphingosine. Biochem J. 1995 Sep 01; 310 ( Pt 2):453-9.
Score: 0.023
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Role for ceramide in cell cycle arrest. J Biol Chem. 1995 Feb 03; 270(5):2047-52.
Score: 0.022
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Identification of a distinct pool of sphingomyelin involved in the sphingomyelin cycle. J Biol Chem. 1994 Sep 23; 269(38):23530-7.
Score: 0.022
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Modulation of cytosolic protein phosphorylation by sphingosylphosphorylcholine. Biochim Biophys Acta. 1994 Mar 10; 1221(1):54-60.
Score: 0.021
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The sphingomyelin cycle and the second messenger function of ceramide. J Biol Chem. 1994 Feb 04; 269(5):3125-8.
Score: 0.021
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Acid sphingomyelinase plays a key role in palmitic acid-amplified inflammatory signaling triggered by lipopolysaccharide at low concentrations in macrophages. Am J Physiol Endocrinol Metab. 2013 Oct 01; 305(7):E853-67.
Score: 0.020
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Selective regulation of expression of protein kinase C beta isoenzymes occurs via alternative splicing. J Biol Chem. 1993 May 15; 268(14):10627-35.
Score: 0.020
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A signaling cascade mediated by ceramide, src and PDGFR? coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1. Biochim Biophys Acta. 2013 Aug; 1831(8):1344-56.
Score: 0.020
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Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine. J Biol Chem. 1992 Nov 25; 267(33):23459-62.
Score: 0.019
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Differential regulation of acid sphingomyelinase in macrophages stimulated with oxidized low-density lipoprotein (LDL) and oxidized LDL immune complexes: role in phagocytosis and cytokine release. Immunology. 2012 May; 136(1):30-45.
Score: 0.018
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Ceramide stimulates a cytosolic protein phosphatase. J Biol Chem. 1992 Mar 15; 267(8):5048-51.
Score: 0.018
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Defining a role for sphingosine kinase 1 in p53-dependent tumors. Oncogene. 2012 Mar 01; 31(9):1166-75.
Score: 0.017
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Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation. J Biol Chem. 1991 Jan 05; 266(1):484-9.
Score: 0.017
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Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation. J Biol Chem. 1990 Sep 15; 265(26):15823-31.
Score: 0.016
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Transcriptional regulation of protein kinase C by 1,25-dihydroxyvitamin D3 in HL-60 cells. J Biol Chem. 1990 Feb 05; 265(4):2370-4.
Score: 0.016
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Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation. J Biol Chem. 1989 Nov 15; 264(32):19076-80.
Score: 0.016
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Defective acid sphingomyelinase pathway with Pseudomonas aeruginosa infection in cystic fibrosis. Am J Respir Cell Mol Biol. 2009 Sep; 41(3):367-75.
Score: 0.015
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Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells. J Biol Chem. 2008 Sep 26; 283(39):26509-17.
Score: 0.014
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Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide. Nature. 2007 Sep 06; 449(7158):62-7.
Score: 0.013
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Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release. J Biol Chem. 2003 Oct 03; 278(40):38206-13.
Score: 0.010
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PKC-dependent activation of sphingosine kinase 1 and translocation to the plasma membrane. Extracellular release of sphingosine-1-phosphate induced by phorbol 12-myristate 13-acetate (PMA). J Biol Chem. 2002 Sep 20; 277(38):35257-62.
Score: 0.009
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Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate. J Biol Chem. 2001 Sep 21; 276(38):35258-64.
Score: 0.009
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Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans. Genes Dev. 2001 Jan 15; 15(2):201-12.
Score: 0.008
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Functional dichotomy of protein kinase C (PKC) in tumor necrosis factor-alpha (TNF-alpha ) signal transduction in L929 cells. Translocation and inactivation of PKC by TNF-alpha. J Biol Chem. 2000 Sep 22; 275(38):29290-8.
Score: 0.008
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A novel assay for apoptotic body formation and membrane release during apoptosis. Cell Death Differ. 1999 Jul; 6(7):596-8.
Score: 0.008
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Dual role of ceramide in the control of apoptosis following IL-2 withdrawal. J Immunol. 1998 Apr 01; 160(7):3528-33.
Score: 0.007
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Ceramide inactivates cellular protein kinase Calpha. J Biol Chem. 1996 May 31; 271(22):13169-74.
Score: 0.006
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prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2. Biochem J. 1996 May 15; 316 ( Pt 1):25-8.
Score: 0.006
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12(S)-hydroxyeicosatetraenoic acid and 13(S)-hydroxyoctadecadienoic acid regulation of protein kinase C-alpha in melanoma cells: role of receptor-mediated hydrolysis of inositol phospholipids. Proc Natl Acad Sci U S A. 1995 Sep 26; 92(20):9323-7.
Score: 0.006
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Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity. Proc Natl Acad Sci U S A. 1995 Aug 29; 92(18):8443-7.
Score: 0.006
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Regulation of protein kinase C (PKC) expression by iron: effect of different iron compounds on PKC-beta and PKC-alpha gene expression and role of the 5'-flanking region of the PKC-beta gene in the response to ferric transferrin. Blood. 1994 Nov 15; 84(10):3510-7.
Score: 0.005
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Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases. J Biol Chem. 1986 Sep 25; 261(27):12610-5.
Score: 0.003