Connection

Yusuf Hannun to Structure-Activity Relationship

This is a "connection" page, showing publications Yusuf Hannun has written about Structure-Activity Relationship.
Connection Strength

0.774
  1. Synthesis of erythro- B13 enantiomers and stereospecific action of full set of B13-isomers in MCF7 breast carcinoma cells: Cellular metabolism and effects on sphingolipids. Bioorg Med Chem. 2021 02 15; 32:116011.
    View in: PubMed
    Score: 0.170
  2. Multiple actions of doxorubicin on the sphingolipid network revealed by flux analysis. J Lipid Res. 2019 04; 60(4):819-831.
    View in: PubMed
    Score: 0.148
  3. Dose dependent actions of LCL521 on acid ceramidase and key sphingolipid metabolites. Bioorg Med Chem. 2018 12 15; 26(23-24):6067-6075.
    View in: PubMed
    Score: 0.146
  4. Functional analysis of ISC1 by site-directed mutagenesis. Biochemistry. 2003 Jul 01; 42(25):7855-62.
    View in: PubMed
    Score: 0.050
  5. Use of short-chain ceramides. Methods Enzymol. 2000; 312:407-20.
    View in: PubMed
    Score: 0.040
  6. Neurotrophins induce sphingomyelin hydrolysis. Modulation by co-expression of p75NTR with Trk receptors. J Biol Chem. 1995 Sep 22; 270(38):22135-42.
    View in: PubMed
    Score: 0.029
  7. Activation of a retinoblastoma-protein-dependent pathway by sphingosine. Biochem J. 1995 Sep 01; 310 ( Pt 2):453-9.
    View in: PubMed
    Score: 0.029
  8. Activity of neutral and alkaline ceramidases on fluorogenic N-acylated coumarin-containing aminodiols. J Lipid Res. 2015 Oct; 56(10):2019-28.
    View in: PubMed
    Score: 0.029
  9. Ceramide-mediated growth inhibition and CAPP are conserved in Saccharomyces cerevisiae. J Biol Chem. 1993 May 05; 268(13):9255-61.
    View in: PubMed
    Score: 0.025
  10. Regulation of protein kinase C by sphingosine and lysosphingolipids. Clin Chim Acta. 1989 Dec 15; 185(3):333-45.
    View in: PubMed
    Score: 0.020
  11. Aminoacridines, potent inhibitors of protein kinase C. J Biol Chem. 1988 Apr 15; 263(11):5124-31.
    View in: PubMed
    Score: 0.018
  12. Novel analogs of D-e-MAPP and B13. Part 1: synthesis and evaluation as potential anticancer agents. Bioorg Med Chem. 2008 Jan 15; 16(2):1015-31.
    View in: PubMed
    Score: 0.017
  13. Lysosphingolipids inhibit protein kinase C: implications for the sphingolipidoses. Science. 1987 Feb 06; 235(4789):670-4.
    View in: PubMed
    Score: 0.016
  14. Tailoring structure-function and targeting properties of ceramides by site-specific cationization. Bioorg Med Chem. 2006 Nov 01; 14(21):7083-104.
    View in: PubMed
    Score: 0.016
  15. prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2. Biochem J. 1996 May 15; 316 ( Pt 1):25-8.
    View in: PubMed
    Score: 0.008
  16. Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds. Biochemistry. 1989 Apr 18; 28(8):3138-45.
    View in: PubMed
    Score: 0.005
  17. Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases. J Biol Chem. 1986 Sep 25; 261(27):12610-5.
    View in: PubMed
    Score: 0.004
  18. Specificity and mechanism of protein kinase C activation by sn-1,2-diacylglycerols. Proc Natl Acad Sci U S A. 1986 Mar; 83(5):1184-8.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.