Yusuf Hannun to Models, Biological
This is a "connection" page, showing publications Yusuf Hannun has written about Models, Biological.
Connection Strength
1.941
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Substantial contribution of extrinsic risk factors to cancer development. Nature. 2016 Jan 07; 529(7584):43-7.
Score: 0.375
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Computational analysis of sphingolipid pathway systems. Adv Exp Med Biol. 2010; 688:264-75.
Score: 0.248
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Sphingolipids and their metabolism in physiology and disease. Nat Rev Mol Cell Biol. 2018 03; 19(3):175-191.
Score: 0.107
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Mathematical modeling and validation of the ergosterol pathway in Saccharomyces cerevisiae. PLoS One. 2011; 6(12):e28344.
Score: 0.071
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Identification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5. J Biol Chem. 2010 Jun 04; 285(23):17993-8002.
Score: 0.063
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Sphingomyelin metabolism at the plasma membrane: implications for bioactive sphingolipids. FEBS Lett. 2010 May 03; 584(9):1887-94.
Score: 0.061
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Sustained receptor stimulation leads to sequestration of recycling endosomes in a classical protein kinase C- and phospholipase D-dependent manner. J Biol Chem. 2009 Aug 14; 284(33):22322-22331.
Score: 0.060
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Principles of bioactive lipid signalling: lessons from sphingolipids. Nat Rev Mol Cell Biol. 2008 Feb; 9(2):139-50.
Score: 0.054
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Coordination of the dynamics of yeast sphingolipid metabolism during the diauxic shift. Theor Biol Med Model. 2007 Oct 31; 4:42.
Score: 0.053
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Selective substrate supply in the regulation of yeast de novo sphingolipid synthesis. J Biol Chem. 2007 Apr 20; 282(16):12330-40.
Score: 0.051
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Protein kinase C-induced activation of a ceramide/protein phosphatase 1 pathway leading to dephosphorylation of p38 MAPK. J Biol Chem. 2006 Dec 01; 281(48):36793-802.
Score: 0.050
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Sphingolipid-binding proteins. Biochim Biophys Acta. 2006 Aug; 1761(8):927-46.
Score: 0.049
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Simulation and validation of modelled sphingolipid metabolism in Saccharomyces cerevisiae. Nature. 2005 Jan 27; 433(7024):425-30.
Score: 0.044
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Selective inhibition of juxtanuclear translocation of protein kinase C betaII by a negative feedback mechanism involving ceramide formed from the salvage pathway. J Biol Chem. 2005 Jan 28; 280(4):2606-12.
Score: 0.044
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Local correlation of expression profiles with gene annotations--proof of concept for a general conciliatory method. Bioinformatics. 2005 Apr 01; 21(7):1037-45.
Score: 0.043
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Integration of kinetic information on yeast sphingolipid metabolism in dynamical pathway models. J Theor Biol. 2004 Feb 07; 226(3):265-91.
Score: 0.041
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cPKC-dependent sequestration of membrane-recycling components in a subset of recycling endosomes. J Biol Chem. 2003 Dec 26; 278(52):52747-54.
Score: 0.040
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The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind. J Biol Chem. 2002 Jul 19; 277(29):25847-50.
Score: 0.037
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Mitochondria and ceramide: intertwined roles in regulation of apoptosis. Adv Enzyme Regul. 2002; 42:113-29.
Score: 0.036
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Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis. J Biol Chem. 2000 Mar 24; 275(12):9078-84.
Score: 0.032
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Role of sphingolipids in senescence: implication in aging and age-related diseases. J Clin Invest. 2018 07 02; 128(7):2702-2712.
Score: 0.028
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The ceramide activated protein phosphatase Sit4 impairs sphingolipid dynamics, mitochondrial function and lifespan in a yeast model of Niemann-Pick type C1. Biochim Biophys Acta Mol Basis Dis. 2018 Jan; 1864(1):79-88.
Score: 0.027
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Mechanisms of ceramide-mediated apoptosis. Adv Exp Med Biol. 1997; 407:145-9.
Score: 0.025
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Sphingolipid second messengers: tumor suppressor lipids. Adv Exp Med Biol. 1997; 400A:305-12.
Score: 0.025
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Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C. Cell Signal. 1995 Mar; 7(3):171-84.
Score: 0.022
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Protein kinase C: cellular target of the second messenger arachidonic acid? Prostaglandins Leukot Essent Fatty Acids. 1995 Feb-Mar; 52(2-3):129-35.
Score: 0.022
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Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction. J Biol Chem. 1994 Jul 29; 269(30):19605-9.
Score: 0.021
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Bone-specific insulin resistance disrupts whole-body glucose homeostasis via decreased osteocalcin activation. J Clin Invest. 2014 Apr; 124(4):1-13.
Score: 0.021
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The sphingomyelin cycle and the second messenger function of ceramide. J Biol Chem. 1994 Feb 04; 269(5):3125-8.
Score: 0.021
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Coordination of rapid sphingolipid responses to heat stress in yeast. PLoS Comput Biol. 2013; 9(5):e1003078.
Score: 0.020
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Oncogenic K-Ras regulates bioactive sphingolipids in a sphingosine kinase 1-dependent manner. J Biol Chem. 2012 Sep 14; 287(38):31794-803.
Score: 0.019
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Ceramide synthases at the centre of sphingolipid metabolism and biology. Biochem J. 2012 Feb 01; 441(3):789-802.
Score: 0.018
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Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity. J Biol Chem. 2008 Oct 24; 283(43):28806-16.
Score: 0.014
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Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1. J Biol Chem. 2008 May 16; 283(20):13538-48.
Score: 0.014
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Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide. Nature. 2007 Sep 06; 449(7158):62-7.
Score: 0.013
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Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway. Mol Cell Biol. 2007 Apr; 27(8):2997-3007.
Score: 0.013
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Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets. J Biol Chem. 1986 Sep 25; 261(27):12604-9.
Score: 0.012
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Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids. J Biol Chem. 2006 Mar 17; 281(11):7324-31.
Score: 0.012
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Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha. J Biol Chem. 2005 Jul 29; 280(30):27879-87.
Score: 0.011
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Golgi fragmentation is associated with ceramide-induced cellular effects. Mol Biol Cell. 2005 Mar; 16(3):1555-67.
Score: 0.011
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Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53. J Biol Chem. 2004 May 07; 279(19):20546-54.
Score: 0.010
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Mechanism of regulation of protein kinase C by lipid second messengers. Symp Fundam Cancer Res. 1986; 39:145-56.
Score: 0.003