Connection

Christina Johnson to Apoptosis

This is a "connection" page, showing publications Christina Johnson has written about Apoptosis.
Connection Strength

1.465
  1. Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner. J Biol Chem. 2015 May 22; 290(21):13157-67.
    View in: PubMed
    Score: 0.154
  2. Sphingolipids in apoptosis. Exp Oncol. 2012 Oct; 34(3):231-42.
    View in: PubMed
    Score: 0.129
  3. 17-allylamino-17-demethoxygeldanamycin and MEK1/2 inhibitors kill GI tumor cells via Ca2+-dependent suppression of GRP78/BiP and induction of ceramide and reactive oxygen species. Mol Cancer Ther. 2010 May; 9(5):1378-95.
    View in: PubMed
    Score: 0.109
  4. Oxidative stress sensitizes bladder cancer cells to TRAIL mediated apoptosis by down-regulating anti-apoptotic proteins. J Urol. 2009 Sep; 182(3):1178-85.
    View in: PubMed
    Score: 0.103
  5. Combination therapy with TRAIL: Recent developments and potential pitfalls. Cancer Biol Ther. 2009 Jan; 8(1):81-3.
    View in: PubMed
    Score: 0.100
  6. Resistance to TRAIL is associated with defects in ceramide signaling that can be overcome by exogenous C6-ceramide without requiring down-regulation of cellular FLICE inhibitory protein. Mol Cancer Ther. 2005 Sep; 4(9):1320-7.
    View in: PubMed
    Score: 0.079
  7. In vitro efficacy of Fas ligand gene therapy for the treatment of bladder cancer. Cancer Gene Ther. 2005 Jan; 12(1):12-8.
    View in: PubMed
    Score: 0.075
  8. Enhanced apoptosis of glioma cell lines is achieved by co-delivering FasL-GFP and TRAIL with a complex Ad5 vector. Cancer Gene Ther. 2003 Nov; 10(11):814-22.
    View in: PubMed
    Score: 0.070
  9. An antibody against DR4 (TRAIL-R1) in combination with doxorubicin selectively kills malignant but not normal prostate cells. Cancer Biol Ther. 2003 May-Jun; 2(3):283-90.
    View in: PubMed
    Score: 0.067
  10. Doxorubicin pretreatment sensitizes prostate cancer cell lines to TRAIL induced apoptosis which correlates with the loss of c-FLIP expression. Cancer Biol Ther. 2002 Sep-Oct; 1(5):520-7.
    View in: PubMed
    Score: 0.064
  11. Resistance of prostate cancer cells to soluble TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) can be overcome by doxorubicin or adenoviral delivery of full-length TRAIL. Cancer Gene Ther. 2002 Feb; 9(2):164-72.
    View in: PubMed
    Score: 0.062
  12. Intracellular Fas ligand expression causes Fas-mediated apoptosis in human prostate cancer cells resistant to monoclonal antibody-induced apoptosis. Mol Ther. 2000 Oct; 2(4):348-58.
    View in: PubMed
    Score: 0.056
  13. The activity of cytosolic phospholipase A2 is required for the lysis of adenovirus-infected cells by tumor necrosis factor. J Virol. 1996 Dec; 70(12):8502-7.
    View in: PubMed
    Score: 0.043
  14. Activation of intracellular proteases is an early event in TNF-induced apoptosis. J Immunol. 1995 Feb 15; 154(4):1707-16.
    View in: PubMed
    Score: 0.038
  15. Sphingosine kinase-2 maintains viral latency and survival for KSHV-infected endothelial cells. PLoS One. 2014; 9(7):e102314.
    View in: PubMed
    Score: 0.036
  16. Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma. Mol Cancer Ther. 2014 Jan; 13(1):154-64.
    View in: PubMed
    Score: 0.035
  17. Inner ear supporting cells protect hair cells by secreting HSP70. J Clin Invest. 2013 Aug; 123(8):3577-87.
    View in: PubMed
    Score: 0.034
  18. T cells expanded in presence of IL-15 exhibit increased antioxidant capacity and innate effector molecules. Cytokine. 2011 Aug; 55(2):307-17.
    View in: PubMed
    Score: 0.029
  19. MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism. Mol Cancer Ther. 2009 May; 8(5):1280-91.
    View in: PubMed
    Score: 0.025
  20. Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells. Oncogene. 2009 Feb 26; 28(8):1132-41.
    View in: PubMed
    Score: 0.025
  21. Transformation, translation and TRAIL: an unexpected intersection. Cytokine Growth Factor Rev. 2008 Apr; 19(2):167-72.
    View in: PubMed
    Score: 0.024
  22. Doxorubicin generates a proapoptotic phenotype by phosphorylation of elongation factor 2. Free Radic Biol Med. 2007 Nov 01; 43(9):1313-21.
    View in: PubMed
    Score: 0.022
  23. The histone deacetylase inhibitors depsipeptide and MS-275, enhance TRAIL gene therapy of LNCaP prostate cancer cells without adverse effects in normal prostate epithelial cells. Cancer Gene Ther. 2007 Mar; 14(3):327-34.
    View in: PubMed
    Score: 0.022
  24. Targeting the short form of cFLIP by RNA interference is sufficient to enhance TRAIL sensitivity in PC3 prostate carcinoma cells. Cancer Biol Ther. 2006 Dec; 5(12):1618-23.
    View in: PubMed
    Score: 0.022
  25. In vitro efficacy of AdTRAIL gene therapy of bladder cancer is enhanced by trichostatin A-mediated restoration of CAR expression and downregulation of cFLIP and Bcl-XL. Cancer Gene Ther. 2006 Mar; 13(3):281-9.
    View in: PubMed
    Score: 0.020
  26. The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo. Mol Cancer Ther. 2015 Dec; 14(12):2744-52.
    View in: PubMed
    Score: 0.020
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.