Connection

Andrew Kraft to Mice

This is a "connection" page, showing publications Andrew Kraft has written about Mice.
Connection Strength

1.239
  1. Small-Molecule-Targeting Hairpin Loop of hTERT Promoter G-Quadruplex Induces Cancer Cell Death. Cell Chem Biol. 2019 08 15; 26(8):1110-1121.e4.
    View in: PubMed
    Score: 0.070
  2. Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset. Oncotarget. 2017 May 02; 8(18):30199-30216.
    View in: PubMed
    Score: 0.060
  3. PIM Kinase Inhibitors Kill Hypoxic Tumor Cells by Reducing Nrf2 Signaling and Increasing Reactive Oxygen Species. Mol Cancer Ther. 2016 07; 15(7):1637-47.
    View in: PubMed
    Score: 0.056
  4. Insulin receptor substrate 1 is a substrate of the Pim protein kinases. Oncotarget. 2016 Apr 12; 7(15):20152-65.
    View in: PubMed
    Score: 0.056
  5. Deletion of Pim kinases elevates the cellular levels of reactive oxygen species and sensitizes to K-Ras-induced cell killing. Oncogene. 2015 Jul; 34(28):3728-36.
    View in: PubMed
    Score: 0.050
  6. The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling. Mol Cell Biol. 2014 Jul; 34(13):2517-32.
    View in: PubMed
    Score: 0.049
  7. Elevation of receptor tyrosine kinases by small molecule AKT inhibitors in prostate cancer is mediated by Pim-1. Cancer Res. 2013 Jun 01; 73(11):3402-11.
    View in: PubMed
    Score: 0.046
  8. The Pim protein kinases regulate energy metabolism and cell growth. Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2):528-33.
    View in: PubMed
    Score: 0.039
  9. Regulation of Skp2 levels by the Pim-1 protein kinase. J Biol Chem. 2010 Sep 17; 285(38):29128-37.
    View in: PubMed
    Score: 0.038
  10. p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase. Mol Cancer Res. 2010 Aug; 8(8):1126-41.
    View in: PubMed
    Score: 0.038
  11. A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma. Blood. 2010 Jan 28; 115(4):824-33.
    View in: PubMed
    Score: 0.036
  12. PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells. Cancer Biol Ther. 2009 May; 8(9):846-53.
    View in: PubMed
    Score: 0.035
  13. Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A. Oncogene. 2007 Aug 02; 26(35):5145-53.
    View in: PubMed
    Score: 0.030
  14. Pim family kinases enhance tumor growth of prostate cancer cells. Mol Cancer Res. 2005 Aug; 3(8):443-51.
    View in: PubMed
    Score: 0.027
  15. Phosphorylation of AML1/RUNX1 regulates its degradation and nuclear matrix association. Mol Cancer Res. 2005 Jul; 3(7):391-401.
    View in: PubMed
    Score: 0.027
  16. The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim. Mol Cancer Ther. 2005 Mar; 4(3):443-9.
    View in: PubMed
    Score: 0.026
  17. An XBP1s-PIM-2 positive feedback loop controls IL-15-mediated survival of natural killer cells. Sci Immunol. 2023 03 17; 8(81):eabn7993.
    View in: PubMed
    Score: 0.023
  18. Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects. Anticancer Res. 2003 Jan-Feb; 23(1A):167-78.
    View in: PubMed
    Score: 0.022
  19. Distinct domains of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit mediate activation of Jak/Stat signaling and differentiation. Blood. 2001 Mar 15; 97(6):1662-70.
    View in: PubMed
    Score: 0.020
  20. Regulation of dual-specificity phosphatases M3/6 and hVH5 by phorbol esters. Analysis of a delta-like domain. J Biol Chem. 2000 Oct 13; 275(41):31755-62.
    View in: PubMed
    Score: 0.019
  21. PIM Kinase Inhibitors Block the Growth of Primary T-cell Acute Lymphoblastic Leukemia: Resistance Pathways Identified by Network Modeling Analysis. Mol Cancer Ther. 2020 09; 19(9):1809-1821.
    View in: PubMed
    Score: 0.019
  22. Phosphorylation of DEPDC5, a component of the GATOR1 complex, releases inhibition of mTORC1 and promotes tumor growth. Proc Natl Acad Sci U S A. 2019 10 08; 116(41):20505-20510.
    View in: PubMed
    Score: 0.018
  23. The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway. Oncogene. 1999 Jul 08; 18(27):4022-31.
    View in: PubMed
    Score: 0.018
  24. Regulation of myeloid cell growth by distinct effectors of Ras. Oncogene. 1998 Nov 26; 17(21):2701-9.
    View in: PubMed
    Score: 0.017
  25. Activation of the mitogen-activated protein kinase pathway in U937 leukemic cells induces phosphorylation of the amino terminus of the TATA-binding protein. Cell Growth Differ. 1998 Aug; 9(8):667-76.
    View in: PubMed
    Score: 0.016
  26. Cytoplasmic domains of the human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor beta chain (hbetac) responsible for human GM-CSF-induced myeloid cell differentiation. J Biol Chem. 1998 Jul 31; 273(31):19411-8.
    View in: PubMed
    Score: 0.016
  27. PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity. J Clin Invest. 2018 07 02; 128(7):2787-2801.
    View in: PubMed
    Score: 0.016
  28. Inhibition of caspases by cytokine response modifier A blocks androgen ablation-mediated prostate cancer cell death in vivo. Cancer Res. 1998 Feb 15; 58(4):834-9.
    View in: PubMed
    Score: 0.016
  29. Treatment of human prostate cancer cells with dolastatin 10, a peptide isolated from a marine shell-less mollusc. Prostate. 1998 Feb 15; 34(3):175-81.
    View in: PubMed
    Score: 0.016
  30. Enforced expression of the Mr 33,000 Pim-1 kinase enhances factor-independent survival and inhibits apoptosis in murine myeloid cells. Cancer Res. 1997 Dec 01; 57(23):5348-55.
    View in: PubMed
    Score: 0.016
  31. Hypoxia-Inducible PIM Kinase Expression Promotes Resistance to Antiangiogenic Agents. Clin Cancer Res. 2018 01 01; 24(1):169-180.
    View in: PubMed
    Score: 0.016
  32. The cytoplasmic domain of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha subunit is essential for both GM-CSF-mediated growth and differentiation. J Biol Chem. 1997 Jul 11; 272(28):17450-9.
    View in: PubMed
    Score: 0.015
  33. Biological activity of 26-succinylbryostatin 1. Biochim Biophys Acta. 1996 Jul 24; 1312(3):197-206.
    View in: PubMed
    Score: 0.014
  34. Preclinical pharmacology of the natural product anticancer agent bryostatin 1, an activator of protein kinase C. Cancer Res. 1996 Feb 15; 56(4):802-8.
    View in: PubMed
    Score: 0.014
  35. Activation of Pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors. Cancer Res. 2015 Dec 15; 75(24):5318-28.
    View in: PubMed
    Score: 0.014
  36. Signal transduction by a CD16/CD7/Jak2 fusion protein. J Biol Chem. 1995 Aug 04; 270(31):18420-7.
    View in: PubMed
    Score: 0.013
  37. Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor. J Biol Chem. 1995 Jun 16; 270(24):14776-85.
    View in: PubMed
    Score: 0.013
  38. Minocycline reduces spontaneous hemorrhage in mouse models of cerebral amyloid angiopathy. Stroke. 2015 Jun; 46(6):1633-1640.
    View in: PubMed
    Score: 0.013
  39. The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets. Oncotarget. 2014 Sep 30; 5(18):8503-14.
    View in: PubMed
    Score: 0.013
  40. Reducing CD73 expression by IL1?-Programmed Th17 cells improves immunotherapeutic control of tumors. Cancer Res. 2014 Nov 01; 74(21):6048-59.
    View in: PubMed
    Score: 0.013
  41. Metabolic dysfunction consistent with premature aging results from deletion of Pim kinases. Circ Res. 2014 Jul 18; 115(3):376-87.
    View in: PubMed
    Score: 0.012
  42. Mapping the intracytoplasmic regions of the alpha granulocyte-macrophage colony-stimulating factor receptor necessary for cell growth regulation. J Biol Chem. 1994 May 20; 269(20):14607-13.
    View in: PubMed
    Score: 0.012
  43. In vivo administration of the anticancer agent bryostatin 1 activates platelets and neutrophils and modulates protein kinase C activity. Cancer Res. 1993 Jun 15; 53(12):2810-5.
    View in: PubMed
    Score: 0.012
  44. A critical role for the cytoplasmic domain of the granulocyte-macrophage colony-stimulating factor alpha receptor in mediating cell growth. Cell Growth Differ. 1993 Jun; 4(6):523-31.
    View in: PubMed
    Score: 0.011
  45. Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells. Stem Cells. 2013 Jun; 31(6):1202-12.
    View in: PubMed
    Score: 0.011
  46. Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice. J Hematol Oncol. 2013 Jan 29; 6:12.
    View in: PubMed
    Score: 0.011
  47. Phorbol ester-induced amino-terminal phosphorylation of human JUN but not JUNB regulates transcriptional activation. Proc Natl Acad Sci U S A. 1992 Aug 01; 89(15):7247-51.
    View in: PubMed
    Score: 0.011
  48. Collaboration of Kras and androgen receptor signaling stimulates EZH2 expression and tumor-propagating cells in prostate cancer. Cancer Res. 2012 Sep 15; 72(18):4672-81.
    View in: PubMed
    Score: 0.011
  49. In vivo administration of bryostatin 1, a protein kinase C activator, decreases murine resistance to Salmonella typhimurium. Cancer Res. 1992 Apr 15; 52(8):2143-7.
    View in: PubMed
    Score: 0.011
  50. Multiple phosphorylation sites are important for RUNX1 activity in early hematopoiesis and T-cell differentiation. Eur J Immunol. 2012 Apr; 42(4):1044-50.
    View in: PubMed
    Score: 0.011
  51. Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. J Med Chem. 2009 Jan 08; 52(1):74-86.
    View in: PubMed
    Score: 0.008
  52. Production of multilineage hemopoietic growth-stimulating activities by a human melanoma cell line. Exp Hematol. 1986 Oct; 14(9):867-72.
    View in: PubMed
    Score: 0.007
  53. AML1/RUNX1 phosphorylation by cyclin-dependent kinases regulates the degradation of AML1/RUNX1 by the anaphase-promoting complex. Mol Cell Biol. 2006 Oct; 26(20):7420-9.
    View in: PubMed
    Score: 0.007
  54. The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death. J Biol Chem. 2003 Nov 14; 278(46):45358-67.
    View in: PubMed
    Score: 0.006
  55. Decrease in cytosolic calcium/phospholipid-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells. J Biol Chem. 1982 Nov 25; 257(22):13193-6.
    View in: PubMed
    Score: 0.006
  56. A novel mitogen-activated protein kinase phosphatase is an important negative regulator of lipopolysaccharide-mediated c-Jun N-terminal kinase activation in mouse macrophage cell lines. Mol Cell Biol. 2001 Oct; 21(20):6999-7009.
    View in: PubMed
    Score: 0.005
  57. The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter. J Biol Chem. 2000 Jun 16; 275(24):18391-8.
    View in: PubMed
    Score: 0.005
  58. Adenovirus-mediated expression of Fas ligand induces apoptosis of human prostate cancer cells. Cell Death Differ. 1999 Feb; 6(2):175-82.
    View in: PubMed
    Score: 0.004
  59. Regulation of the c-jun gene in p210 BCR-ABL transformed cells corresponds with activity of JNK, the c-jun N-terminal kinase. Blood. 1998 Oct 01; 92(7):2450-60.
    View in: PubMed
    Score: 0.004
  60. Interleukin-3 and bryostatin 1 mediate rapid nuclear envelope protein phosphorylation in growth factor-dependent FDC-P1 hematopoietic cells. A possible role for nuclear protein kinase C. J Biol Chem. 1989 Dec 25; 264(36):21896-901.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.