Connection

John Lemasters to Hepatocytes

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This is a "connection" page, showing publications John Lemasters has written about Hepatocytes.
John Lemasters
Connection Strength
7.048
Hepatocytes
  1. ATP/ADP Turnover and Import of Glycolytic ATP into Mitochondria in Cancer Cells Is Independent of the Adenine Nucleotide Translocator. J Biol Chem. 2016 09 09; 291(37):19642-50.
    View in: PubMed
    Score: 0.462
  2. Minocycline and doxycycline, but not other tetracycline-derived compounds, protect liver cells from chemical hypoxia and ischemia/reperfusion injury by inhibition of the mitochondrial calcium uniporter. Toxicol Appl Pharmacol. 2013 Nov 15; 273(1):172-9.
    View in: PubMed
    Score: 0.378
  3. Translocation of iron from lysosomes to mitochondria during ischemia predisposes to injury after reperfusion in rat hepatocytes. Free Radic Biol Med. 2013 Oct; 63:243-53.
    View in: PubMed
    Score: 0.370
  4. Mitochondrial permeability transition in rat hepatocytes after anoxia/reoxygenation: role of Ca2+-dependent mitochondrial formation of reactive oxygen species. Am J Physiol Gastrointest Liver Physiol. 2012 Apr; 302(7):G723-31.
    View in: PubMed
    Score: 0.337
  5. Ethanol suppresses ureagenesis in rat hepatocytes: role of acetaldehyde. J Biol Chem. 2012 Mar 02; 287(10):7692-700.
    View in: PubMed
    Score: 0.337
  6. Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation. Am J Physiol Cell Physiol. 2011 Feb; 300(2):C308-17.
    View in: PubMed
    Score: 0.312
  7. Inhibition of the mitochondrial permeability transition by protein kinase A in rat liver mitochondria and hepatocytes. Biochem J. 2010 Nov 01; 431(3):411-21.
    View in: PubMed
    Score: 0.311
  8. Lysosomal iron mobilization and induction of the mitochondrial permeability transition in acetaminophen-induced toxicity to mouse hepatocytes. Toxicol Sci. 2010 Sep; 117(1):101-8.
    View in: PubMed
    Score: 0.303
  9. Roles of mitophagy and the mitochondrial permeability transition in remodeling of cultured rat hepatocytes. Autophagy. 2009 Nov; 5(8):1099-106.
    View in: PubMed
    Score: 0.290
  10. Ethanol exposure decreases mitochondrial outer membrane permeability in cultured rat hepatocytes. Arch Biochem Biophys. 2009 Jan 15; 481(2):226-33.
    View in: PubMed
    Score: 0.271
  11. Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury. Hepatology. 2008 Nov; 48(5):1644-54.
    View in: PubMed
    Score: 0.270
  12. Opioid receptor-independent protection of ischemic rat hepatocytes by morphine. Biochem Biophys Res Commun. 2006 Dec 29; 351(4):958-64.
    View in: PubMed
    Score: 0.236
  13. Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes. Autophagy. 2006 Jan-Mar; 2(1):39-46.
    View in: PubMed
    Score: 0.223
  14. Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes. Hepatology. 2004 Nov; 40(5):1170-9.
    View in: PubMed
    Score: 0.205
  15. Nitric oxide protects rat hepatocytes against reperfusion injury mediated by the mitochondrial permeability transition. Hepatology. 2004 Jun; 39(6):1533-43.
    View in: PubMed
    Score: 0.199
  16. Rusty notions of cell injury. J Hepatol. 2004 Apr; 40(4):696-8.
    View in: PubMed
    Score: 0.197
  17. Role of the mitochondrial permeability transition in apoptotic and necrotic death after ischemia/reperfusion injury to hepatocytes. Curr Mol Med. 2003 Sep; 3(6):527-35.
    View in: PubMed
    Score: 0.189
  18. Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes. Gastroenterology. 2003 Feb; 124(2):494-503.
    View in: PubMed
    Score: 0.182
  19. Kupffer cells mediate increased anoxic hepatocellular killing from hyperosmolarity by an oxygen- and prostaglandin-independent mechanism. Toxicol Lett. 2000 Sep 30; 117(1-2):95-100.
    View in: PubMed
    Score: 0.154
  20. Suppression of iron mobilization from lysosomes to mitochondria attenuates liver injury after acetaminophen overdose in vivo in mice: Protection by minocycline. Toxicol Appl Pharmacol. 2020 04 01; 392:114930.
    View in: PubMed
    Score: 0.148
  21. A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome. Cell Rep. 2018 11 06; 25(6):1469-1484.e5.
    View in: PubMed
    Score: 0.135
  22. Translocation of iron from lysosomes to mitochondria during acetaminophen-induced hepatocellular injury: Protection by starch-desferal and minocycline. Free Radic Biol Med. 2016 08; 97:418-426.
    View in: PubMed
    Score: 0.115
  23. Acute ethanol causes hepatic mitochondrial depolarization in mice: role of ethanol metabolism. PLoS One. 2014; 9(3):e91308.
    View in: PubMed
    Score: 0.098
  24. Lysosomal instability and cathepsin B release during acetaminophen hepatotoxicity. Basic Clin Pharmacol Toxicol. 2012 Dec; 111(6):417-25.
    View in: PubMed
    Score: 0.089
  25. Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity. Toxicol Sci. 2011 Aug; 122(2):598-605.
    View in: PubMed
    Score: 0.081
  26. Mitophagy selectively degrades individual damaged mitochondria after photoirradiation. Antioxid Redox Signal. 2011 May 15; 14(10):1919-28.
    View in: PubMed
    Score: 0.080
  27. [The role of the voltage-dependent anion channels in the outer membrane of mitochondria in the regulation of cellular metabolism]. Biofizika. 2010 Sep-Oct; 55(5):822-33.
    View in: PubMed
    Score: 0.077
  28. The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes. Toxicol Sci. 2010 Oct; 117(2):515-23.
    View in: PubMed
    Score: 0.076
  29. Mechanisms of pathogenesis in drug hepatotoxicity putting the stress on mitochondria. Mol Interv. 2010 Apr; 10(2):98-111.
    View in: PubMed
    Score: 0.075
  30. Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species. Biochimie. 2007 Dec; 89(12):1464-73.
    View in: PubMed
    Score: 0.062
  31. NIM811, a mitochondrial permeability transition inhibitor, prevents mitochondrial depolarization in small-for-size rat liver grafts. Am J Transplant. 2007 May; 7(5):1103-11.
    View in: PubMed
    Score: 0.061
  32. Increased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice. Exp Mol Pathol. 2007 Apr; 82(2):210-9.
    View in: PubMed
    Score: 0.059
  33. Basal reactive oxygen species determine the susceptibility to apoptosis in cirrhotic hepatocytes. Free Radic Biol Med. 2006 Dec 01; 41(11):1645-54.
    View in: PubMed
    Score: 0.058
  34. Nuclear translocation of endonuclease G and apoptosis-inducing factor during acetaminophen-induced liver cell injury. Toxicol Sci. 2006 Nov; 94(1):217-25.
    View in: PubMed
    Score: 0.058
  35. Acetaminophen-induced oxidant stress and cell injury in cultured mouse hepatocytes: protection by N-acetyl cysteine. Toxicol Sci. 2004 Aug; 80(2):343-9.
    View in: PubMed
    Score: 0.049
  36. Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer. Arch Biochem Biophys. 2004 Feb 15; 422(2):145-52.
    View in: PubMed
    Score: 0.049
  37. Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes. FASEB J. 2004 Apr; 18(6):720-2.
    View in: PubMed
    Score: 0.049
  38. Bid activates multiple mitochondrial apoptotic mechanisms in primary hepatocytes after death receptor engagement. Gastroenterology. 2003 Sep; 125(3):854-67.
    View in: PubMed
    Score: 0.047
  39. Mitochondrial permeability transition: a common pathway to necrosis and apoptosis. Biochem Biophys Res Commun. 2003 May 09; 304(3):463-70.
    View in: PubMed
    Score: 0.046
  40. Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition. Toxicol Sci. 2003 May; 73(1):44-52.
    View in: PubMed
    Score: 0.046
  41. Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy. Antioxid Redox Signal. 2002 Oct; 4(5):769-81.
    View in: PubMed
    Score: 0.044
  42. The role of Iron in lipid peroxidation and protein nitration during acetaminophen-induced liver injury in mice. Toxicol Appl Pharmacol. 2022 06 15; 445:116043.
    View in: PubMed
    Score: 0.043
  43. Mechanisms of hepatotoxicity. Toxicol Sci. 2002 Feb; 65(2):166-76.
    View in: PubMed
    Score: 0.042
  44. NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis. Gastroenterology. 2001 Apr; 120(5):1251-62.
    View in: PubMed
    Score: 0.040
  45. Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells. Biochem Pharmacol. 2018 02; 148:155-162.
    View in: PubMed
    Score: 0.032
  46. Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion. J Hepatol. 2012 Jan; 56(1):137-45.
    View in: PubMed
    Score: 0.020
  47. NIM811 (N-methyl-4-isoleucine cyclosporine), a mitochondrial permeability transition inhibitor, attenuates cholestatic liver injury but not fibrosis in mice. J Pharmacol Exp Ther. 2008 Dec; 327(3):699-706.
    View in: PubMed
    Score: 0.017
  48. Role of pH in protection by low sodium against hypoxic injury in isolated perfused rat livers. J Hepatol. 2006 May; 44(5):894-901.
    View in: PubMed
    Score: 0.014
  49. Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism. J Hepatol. 2004 Jun; 40(6):942-51.
    View in: PubMed
    Score: 0.012
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

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