John Lemasters to Mitochondria, Liver
This is a "connection" page, showing publications John Lemasters has written about Mitochondria, Liver.
Connection Strength
12.172
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Glutamate contributes to alcohol hepatotoxicity by enhancing oxidative stress in mitochondria. J Bioenerg Biomembr. 2017 Jun; 49(3):253-264.
Score: 0.511
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ATP/ADP Turnover and Import of Glycolytic ATP into Mitochondria in Cancer Cells Is Independent of the Adenine Nucleotide Translocator. J Biol Chem. 2016 09 09; 291(37):19642-50.
Score: 0.484
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Low Dose Acetaminophen Induces Reversible Mitochondrial Dysfunction Associated with Transient c-Jun N-Terminal Kinase Activation in Mouse Liver. Toxicol Sci. 2016 Mar; 150(1):204-15.
Score: 0.465
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Acute ethanol causes hepatic mitochondrial depolarization in mice: role of ethanol metabolism. PLoS One. 2014; 9(3):e91308.
Score: 0.411
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Isolated mitochondria infusion mitigates ischemia-reperfusion injury of the liver in rats: mitotracker probes and mitochondrial membrane potential. Shock. 2013 Jun; 39(6):543.
Score: 0.389
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Translocation of iron from lysosomes to mitochondria during ischemia predisposes to injury after reperfusion in rat hepatocytes. Free Radic Biol Med. 2013 Oct; 63:243-53.
Score: 0.387
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Mitochondrial permeability transition in rat hepatocytes after anoxia/reoxygenation: role of Ca2+-dependent mitochondrial formation of reactive oxygen species. Am J Physiol Gastrointest Liver Physiol. 2012 Apr; 302(7):G723-31.
Score: 0.353
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Ethanol suppresses ureagenesis in rat hepatocytes: role of acetaldehyde. J Biol Chem. 2012 Mar 02; 287(10):7692-700.
Score: 0.353
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Mitophagy selectively degrades individual damaged mitochondria after photoirradiation. Antioxid Redox Signal. 2011 May 15; 14(10):1919-28.
Score: 0.333
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Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation. Am J Physiol Cell Physiol. 2011 Feb; 300(2):C308-17.
Score: 0.327
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Inhibition of the mitochondrial permeability transition by protein kinase A in rat liver mitochondria and hepatocytes. Biochem J. 2010 Nov 01; 431(3):411-21.
Score: 0.325
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[The role of the voltage-dependent anion channels in the outer membrane of mitochondria in the regulation of cellular metabolism]. Biofizika. 2010 Sep-Oct; 55(5):822-33.
Score: 0.322
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Roles of mitophagy and the mitochondrial permeability transition in remodeling of cultured rat hepatocytes. Autophagy. 2009 Nov; 5(8):1099-106.
Score: 0.304
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Ethanol exposure decreases mitochondrial outer membrane permeability in cultured rat hepatocytes. Arch Biochem Biophys. 2009 Jan 15; 481(2):226-33.
Score: 0.284
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Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury. Hepatology. 2008 Nov; 48(5):1644-54.
Score: 0.283
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Activation of the oxygen-sensing signal cascade prevents mitochondrial injury after mouse liver ischemia-reperfusion. Am J Physiol Gastrointest Liver Physiol. 2008 Oct; 295(4):G823-32.
Score: 0.280
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Mitochondrial permeability transition in liver ischemia and reperfusion: role of c-Jun N-terminal kinase 2. Transplantation. 2008 May 27; 85(10):1500-4.
Score: 0.275
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Modulation of mitochondrial membrane permeability in pathogenesis, autophagy and control of metabolism. J Gastroenterol Hepatol. 2007 Jun; 22 Suppl 1:S31-7.
Score: 0.257
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NIM811, a mitochondrial permeability transition inhibitor, prevents mitochondrial depolarization in small-for-size rat liver grafts. Am J Transplant. 2007 May; 7(5):1103-11.
Score: 0.255
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Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes. Autophagy. 2006 Jan-Mar; 2(1):39-46.
Score: 0.233
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Dephosphorylation of the Rieske iron-sulfur protein after induction of the mitochondrial permeability transition. Biochem Biophys Res Commun. 2005 Sep 02; 334(3):829-37.
Score: 0.227
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Isolated mouse liver mitochondria are devoid of glucokinase. Biochem Biophys Res Commun. 2005 Sep 02; 334(3):907-10.
Score: 0.227
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Nitric oxide protects rat hepatocytes against reperfusion injury mediated by the mitochondrial permeability transition. Hepatology. 2004 Jun; 39(6):1533-43.
Score: 0.209
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Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer. Arch Biochem Biophys. 2004 Feb 15; 422(2):145-52.
Score: 0.204
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Role of the mitochondrial permeability transition in apoptotic and necrotic death after ischemia/reperfusion injury to hepatocytes. Curr Mol Med. 2003 Sep; 3(6):527-35.
Score: 0.198
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Heat shock suppresses the permeability transition in rat liver mitochondria. J Biol Chem. 2003 May 09; 278(19):16755-60.
Score: 0.191
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Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes. Gastroenterology. 2003 Feb; 124(2):494-503.
Score: 0.190
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Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function? FEBS Lett. 2002 Feb 13; 512(1-3):1-7.
Score: 0.178
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Aldehyde dehydrogenase-2 activation decreases acetaminophen hepatotoxicity by prevention of mitochondrial depolarization. Toxicol Appl Pharmacol. 2020 06 01; 396:114982.
Score: 0.156
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Negative contrast imaging of mitochondria by confocal microscopy. Biophys J. 1999 Sep; 77(3):1747-50.
Score: 0.150
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V. Necrapoptosis and the mitochondrial permeability transition: shared pathways to necrosis and apoptosis. Am J Physiol. 1999 01; 276(1):G1-6.
Score: 0.143
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The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release. Mol Cell Biol. 1998 Nov; 18(11):6353-64.
Score: 0.142
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The mitochondrial permeability transition: from biochemical curiosity to pathophysiological mechanism. Gastroenterology. 1998 Sep; 115(3):783-6.
Score: 0.140
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Mitochondrial dysfunction and cytoskeletal disruption during chemical hypoxia to cultured rat hepatic sinusoidal endothelial cells: the pH paradox and cytoprotection by glucose, acidotic pH, and glycine. Hepatology. 1998 Apr; 27(4):1039-49.
Score: 0.136
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Mitochondrial permeability transition in pH-dependent reperfusion injury to rat hepatocytes. Am J Physiol. 1997 12; 273(6):C1783-92.
Score: 0.133
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Role of the mitochondrial permeability transition in salicylate toxicity to cultured rat hepatocytes: implications for the pathogenesis of Reye's syndrome. Toxicol Appl Pharmacol. 1997 Dec; 147(2):431-41.
Score: 0.133
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Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen species. Am J Physiol. 1997 Apr; 272(4 Pt 1):C1286-94.
Score: 0.127
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Effect of the CRAC Peptide, VLNYYVW, on mPTP Opening in Rat Brain and Liver Mitochondria. Int J Mol Sci. 2016 Dec 13; 17(12).
Score: 0.124
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2',3'-Cyclic nucleotide 3'-phosphodiesterase as a messenger of protection of the mitochondrial function during melatonin treatment in aging. Biochim Biophys Acta Biomembr. 2017 Jan; 1859(1):94-103.
Score: 0.123
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The mitochondrial permeability transition: a new pathophysiological mechanism for Reye's syndrome and toxic liver injury. J Pharmacol Exp Ther. 1996 Sep; 278(3):1000-5.
Score: 0.122
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Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide. Biochem J. 1995 Apr 01; 307 ( Pt 1):99-106.
Score: 0.110
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ATP depletion rather than mitochondrial depolarization mediates hepatocyte killing after metabolic inhibition. Am J Physiol. 1994 Jul; 267(1 Pt 1):C67-74.
Score: 0.105
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Minocycline and doxycycline, but not other tetracycline-derived compounds, protect liver cells from chemical hypoxia and ischemia/reperfusion injury by inhibition of the mitochondrial calcium uniporter. Toxicol Appl Pharmacol. 2013 Nov 15; 273(1):172-9.
Score: 0.099
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Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes. Am J Physiol. 1993 Apr; 264(4 Pt 1):C961-7.
Score: 0.096
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Mitochondrial and glycolytic dysfunction in lethal injury to hepatocytes by t-butylhydroperoxide: protection by fructose, cyclosporin A and trifluoperazine. J Pharmacol Exp Ther. 1993 Apr; 265(1):392-400.
Score: 0.096
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Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity. Toxicol Sci. 2011 Aug; 122(2):598-605.
Score: 0.084
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Free tubulin modulates mitochondrial membrane potential in cancer cells. Cancer Res. 2010 Dec 15; 70(24):10192-201.
Score: 0.082
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The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes. Toxicol Sci. 2010 Oct; 117(2):515-23.
Score: 0.080
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Is there release of mitochondrial calcium in toxic injury? Hepatology. 1990 May; 11(5):902-3.
Score: 0.079
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Closure of VDAC causes oxidative stress and accelerates the Ca(2+)-induced mitochondrial permeability transition in rat liver mitochondria. Arch Biochem Biophys. 2010 Mar 15; 495(2):174-81.
Score: 0.077
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An ATP/2e-stoichiometry of 1 1/2 is thermodynamically possible for site 3 of oxidative phosphorylation. Biochem Biophys Res Commun. 1987 Jan 15; 142(1):176-82.
Score: 0.063
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Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes. Nature. 1987 Jan 1-7; 325(6099):78-81.
Score: 0.062
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Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochim Biophys Acta. 1986 Jul 23; 850(3):436-48.
Score: 0.060
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Apoptosis and necrosis in the liver: a tale of two deaths? Hepatology. 2006 Feb; 43(2 Suppl 1):S31-44.
Score: 0.059
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Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity. J Pharmacol Exp Ther. 2005 Nov; 315(2):879-87.
Score: 0.057
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The ATP-to-oxygen stoichiometries of oxidative phosphorylation by rat liver mitochondria. An analysis of ADP-induced oxygen jumps by linear nonequilibrium thermodynamics. J Biol Chem. 1984 Nov 10; 259(21):13123-30.
Score: 0.054
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Rusty notions of cell injury. J Hepatol. 2004 Apr; 40(4):696-8.
Score: 0.052
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Thermodynamic limits to the ATP/site stoichiometries of oxidative phosphorylation by rat liver mitochondria. J Biol Chem. 1984 Mar 10; 259(5):3058-63.
Score: 0.051
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Bid activates multiple mitochondrial apoptotic mechanisms in primary hepatocytes after death receptor engagement. Gastroenterology. 2003 Sep; 125(3):854-67.
Score: 0.049
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The role of Iron in lipid peroxidation and protein nitration during acetaminophen-induced liver injury in mice. Toxicol Appl Pharmacol. 2022 06 15; 445:116043.
Score: 0.045
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Mechanisms of hepatotoxicity. Toxicol Sci. 2002 Feb; 65(2):166-76.
Score: 0.044
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Non-equilibrium thermodynamics of oxidative phosphorylation by inverted inner membrane vesicles of rat liver mitochondria. J Biol Chem. 1981 Dec 25; 256(24):12949-57.
Score: 0.044
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The energized state of rat liver mitochondria. ATP equivalence, uncoupler sensitivity, and decay kinetics. J Biol Chem. 1980 Jun 25; 255(12):5674-80.
Score: 0.040
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Near thermodynamic equilibrium of oxidative phosphorylation by inverted inner membrane vesicles of rat liver mitochondria. FEBS Lett. 1980 Jan 28; 110(1):96-100.
Score: 0.039
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Contribution of increased mitochondrial free Ca2+ to the mitochondrial permeability transition induced by tert-butylhydroperoxide in rat hepatocytes. Hepatology. 1999 May; 29(5):1523-31.
Score: 0.037
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The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy. Biochim Biophys Acta. 1998 Aug 10; 1366(1-2):177-96.
Score: 0.035
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Possible role of the mitochondrial outer membrane as an oncotic regulator of mitochondrial volume. FEBS Lett. 1978 Apr 01; 88(1):10-4.
Score: 0.034
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Continuous measurement and rapid kinetics of ATP synthesis in rat liver mitochondria, mitoplasts and inner membrane vesicles determined by firefly-luciferase luminescence. Eur J Biochem. 1976 Aug 01; 67(1):1-10.
Score: 0.030
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Progression of subcellular changes during chemical hypoxia to cultured rat hepatocytes: a laser scanning confocal microscopic study. Hepatology. 1995 May; 21(5):1361-72.
Score: 0.028
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Synergism of cyclosporin A and phospholipase inhibitors in protection against lethal injury to rat hepatocytes from oxidant chemicals. Res Commun Chem Pathol Pharmacol. 1992 Oct; 78(1):27-38.
Score: 0.023
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Autophagy in alcohol-induced liver diseases. Alcohol Clin Exp Res. 2012 Aug; 36(8):1301-8.
Score: 0.023
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Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion. J Hepatol. 2012 Jan; 56(1):137-45.
Score: 0.021
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Cyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury. Free Radic Res. 2011 Feb; 45(2):156-64.
Score: 0.020
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c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity. Toxicol Appl Pharmacol. 2010 Jul; 246(1-2):8-17.
Score: 0.020
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UCPs--unlikely calcium porters. Nat Cell Biol. 2008 Nov; 10(11):1235-7; author reply 1237-40.
Score: 0.018
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Mitochondrial bax translocation accelerates DNA fragmentation and cell necrosis in a murine model of acetaminophen hepatotoxicity. J Pharmacol Exp Ther. 2008 Jan; 324(1):8-14.
Score: 0.016
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Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species. Biochimie. 2007 Dec; 89(12):1464-73.
Score: 0.016
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Role of apoptosis in acetaminophen hepatotoxicity. J Gastroenterol Hepatol. 2007 Jun; 22 Suppl 1:S49-52.
Score: 0.016
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Increased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice. Exp Mol Pathol. 2007 Apr; 82(2):210-9.
Score: 0.016
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Basal reactive oxygen species determine the susceptibility to apoptosis in cirrhotic hepatocytes. Free Radic Biol Med. 2006 Dec 01; 41(11):1645-54.
Score: 0.015
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Thermodynamics of reverse electron transfer across site 1: ATP/2e- is greater than one. Biochem Biophys Res Commun. 1984 Nov 30; 125(1):8-13.
Score: 0.013
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Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism. J Hepatol. 2004 Jun; 40(6):942-51.
Score: 0.013
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Lateral diffusion of ubiquinone during electron transfer in phospholipid- and ubiquinone-enriched mitochondrial membranes. J Biol Chem. 1982 Sep 25; 257(18):10789-93.
Score: 0.012
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Liposome-mitochondrial inner membrane fusion. Lateral diffusion of integral electron transfer components. J Biol Chem. 1980 Apr 25; 255(8):3748-56.
Score: 0.010
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Fusion of liposomes with mitochondrial inner membranes. Proc Natl Acad Sci U S A. 1980 Jan; 77(1):442-6.
Score: 0.010
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Relationships between bilayer lipid, motional freedom of oxidoreductase components, and electron transfer in the mitochondrial inner membrane. Adv Exp Med Biol. 1980; 132:245-63.
Score: 0.010
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Phosphate dependence and atractyloside inhibition of mitochondrial oxidative phosphorylation. The ADP-ATP carrier is rate-limiting. J Biol Chem. 1979 Feb 25; 254(4):1248-51.
Score: 0.009
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Role of free radicals in primary nonfunction of marginal fatty grafts from rats treated acutely with ethanol. Mol Pharmacol. 1997 Nov; 52(5):912-9.
Score: 0.008
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Novel mechanisms in chemically induced hepatotoxicity. FASEB J. 1994 Dec; 8(15):1285-95.
Score: 0.007