Louis Luttrell to Receptors, G-Protein-Coupled
This is a "connection" page, showing publications Louis Luttrell has written about Receptors, G-Protein-Coupled.
Connection Strength
8.632
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Manifold roles of ?-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9. Sci Signal. 2018 09 25; 11(549).
Score: 0.555
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The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling. Pharmacol Rev. 2017 07; 69(3):256-297.
Score: 0.510
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Translating in vitro ligand bias into in vivo efficacy. Cell Signal. 2018 01; 41:46-55.
Score: 0.505
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GPCR Signaling Rides a Wave of Conformational Changes. Cell. 2016 Oct 20; 167(3):602-603.
Score: 0.486
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The conformational signature of ?-arrestin2 predicts its trafficking and signalling functions. Nature. 2016 Mar 31; 531(7596):665-8.
Score: 0.467
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Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism. Mol Pharmacol. 2015 Sep; 88(3):579-88.
Score: 0.444
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Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation. Methods. 2016 Jan 01; 92:51-63.
Score: 0.440
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Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery. Mol Endocrinol. 2014 Mar; 28(3):281-94.
Score: 0.401
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Emergent biological properties of arrestin pathway-selective biased agonism. J Recept Signal Transduct Res. 2013 Jun; 33(3):153-61.
Score: 0.378
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Brave new world? Arrestin pathway bias in drug design. Endocr Metab Immune Disord Drug Targets. 2011 Jun; 11(2):90-1.
Score: 0.334
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Refining efficacy: allosterism and bias in G protein-coupled receptor signaling. Methods Mol Biol. 2011; 756:3-35.
Score: 0.325
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Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. Mol Biotechnol. 2008 Jul; 39(3):239-64.
Score: 0.266
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Heptahelical terpsichory. Who calls the tune? J Recept Signal Transduct Res. 2008; 28(1-2):39-58.
Score: 0.264
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G protein-coupled receptor signaling complexity in neuronal tissue: implications for novel therapeutics. Curr Alzheimer Res. 2007 Feb; 4(1):3-19.
Score: 0.248
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Constitutive ERK1/2 activation by a chimeric neurokinin 1 receptor-beta-arrestin1 fusion protein. Probing the composition and function of the G protein-coupled receptor "signalsome". J Biol Chem. 2006 Jul 14; 281(28):19346-57.
Score: 0.235
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Transmembrane signaling by G protein-coupled receptors. Methods Mol Biol. 2006; 332:3-49.
Score: 0.230
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The origins of diversity and specificity in g protein-coupled receptor signaling. J Pharmacol Exp Ther. 2005 Aug; 314(2):485-94.
Score: 0.218
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Composition and function of g protein-coupled receptor signalsomes controlling mitogen-activated protein kinase activity. J Mol Neurosci. 2005; 26(2-3):253-64.
Score: 0.214
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Not so strange bedfellows: G-protein-coupled receptors and Src family kinases. Oncogene. 2004 Oct 18; 23(48):7969-78.
Score: 0.211
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'Location, location, location': activation and targeting of MAP kinases by G protein-coupled receptors. J Mol Endocrinol. 2003 Apr; 30(2):117-26.
Score: 0.190
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Signaling in time and space: G protein-coupled receptors and mitogen-activated protein kinases. Assay Drug Dev Technol. 2003 Apr; 1(2):327-38.
Score: 0.190
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Aging-related modifications to G protein-coupled receptor signaling diversity. Pharmacol Ther. 2021 07; 223:107793.
Score: 0.162
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?-Arrestin2 is a critical component of the GPCR-eNOS signalosome. Proc Natl Acad Sci U S A. 2020 05 26; 117(21):11483-11492.
Score: 0.155
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Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases. J Biol Chem. 1996 Aug 09; 271(32):19443-50.
Score: 0.120
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Exploring G protein-coupled receptor signaling networks using SILAC-based phosphoproteomics. Methods. 2016 Jan 01; 92:36-50.
Score: 0.111
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Arrestin-dependent activation of ERK and Src family kinases. Handb Exp Pharmacol. 2014; 219:225-57.
Score: 0.100
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Arrestins as regulators of kinases and phosphatases. Prog Mol Biol Transl Sci. 2013; 118:115-47.
Score: 0.093
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Arrestin pathways as drug targets. Prog Mol Biol Transl Sci. 2013; 118:469-97.
Score: 0.093
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Functional signaling biases in G protein-coupled receptors: Game Theory and receptor dynamics. Mini Rev Med Chem. 2012 Aug; 12(9):831-40.
Score: 0.091
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Refining efficacy: exploiting functional selectivity for drug discovery. Adv Pharmacol. 2011; 62:79-107.
Score: 0.081
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Novel mechanisms in the regulation of G protein-coupled receptor trafficking to the plasma membrane. J Biol Chem. 2010 Oct 29; 285(44):33816-25.
Score: 0.079
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Beyond desensitization: physiological relevance of arrestin-dependent signaling. Pharmacol Rev. 2010 Jun; 62(2):305-30.
Score: 0.078
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Allosteric modulators of g protein-coupled receptors: future therapeutics for complex physiological disorders. J Pharmacol Exp Ther. 2009 Nov; 331(2):340-8.
Score: 0.074
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Diversity in arrestin function. Cell Mol Life Sci. 2009 Sep; 66(18):2953-73.
Score: 0.073
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Transactivation of the epidermal growth factor receptor mediates parathyroid hormone and prostaglandin F2 alpha-stimulated mitogen-activated protein kinase activation in cultured transgenic murine osteoblasts. Mol Endocrinol. 2003 Aug; 17(8):1607-21.
Score: 0.048
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SnapShot: ?-Arrestin Functions. Cell. 2020 09 03; 182(5):1362-1362.e1.
Score: 0.040
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Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. J Biol Chem. 1998 Jan 09; 273(2):685-8.
Score: 0.033
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G(o)-protein alpha-subunits activate mitogen-activated protein kinase via a novel protein kinase C-dependent mechanism. J Biol Chem. 1996 Jan 19; 271(3):1266-9.
Score: 0.029
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?-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivo. Mol Endocrinol. 2013 Feb; 27(2):296-314.
Score: 0.023
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Bradykinin decreases podocyte permeability through ADAM17-dependent epidermal growth factor receptor activation and zonula occludens-1 rearrangement. J Pharmacol Exp Ther. 2010 Sep 01; 334(3):775-83.
Score: 0.020
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c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway. Cell Signal. 2009 Jan; 21(1):103-10.
Score: 0.017