Louis Luttrell to Signal Transduction
This is a "connection" page, showing publications Louis Luttrell has written about Signal Transduction.
Connection Strength
5.743
-
Transcriptomic characterization of signaling pathways associated with osteoblastic differentiation of MC-3T3E1 cells. PLoS One. 2019; 14(1):e0204197.
Score: 0.325
-
Manifold roles of ?-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9. Sci Signal. 2018 09 25; 11(549).
Score: 0.319
-
The conformational signature of ?-arrestin2 predicts its trafficking and signalling functions. Nature. 2016 Mar 31; 531(7596):665-8.
Score: 0.268
-
Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism. Mol Pharmacol. 2015 Sep; 88(3):579-88.
Score: 0.255
-
Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation. Methods. 2016 Jan 01; 92:51-63.
Score: 0.253
-
Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery. Mol Endocrinol. 2014 Mar; 28(3):281-94.
Score: 0.231
-
Emergent biological properties of arrestin pathway-selective biased agonism. J Recept Signal Transduct Res. 2013 Jun; 33(3):153-61.
Score: 0.217
-
Arrestin pathways as drug targets. Prog Mol Biol Transl Sci. 2013; 118:469-97.
Score: 0.215
-
The beta-arrestin pathway-selective type 1A angiotensin receptor (AT1A) agonist [Sar1,Ile4,Ile8]angiotensin II regulates a robust G protein-independent signaling network. J Biol Chem. 2011 Jun 03; 286(22):19880-91.
Score: 0.191
-
Refining efficacy: exploiting functional selectivity for drug discovery. Adv Pharmacol. 2011; 62:79-107.
Score: 0.187
-
Beyond desensitization: physiological relevance of arrestin-dependent signaling. Pharmacol Rev. 2010 Jun; 62(2):305-30.
Score: 0.178
-
Diversity in arrestin function. Cell Mol Life Sci. 2009 Sep; 66(18):2953-73.
Score: 0.169
-
Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. Mol Biotechnol. 2008 Jul; 39(3):239-64.
Score: 0.153
-
Heptahelical terpsichory. Who calls the tune? J Recept Signal Transduct Res. 2008; 28(1-2):39-58.
Score: 0.152
-
G protein-coupled receptor signaling complexity in neuronal tissue: implications for novel therapeutics. Curr Alzheimer Res. 2007 Feb; 4(1):3-19.
Score: 0.142
-
Signal switching, crosstalk, and arrestin scaffolds: novel G protein-coupled receptor signaling in cardiovascular disease. Hypertension. 2006 Aug; 48(2):173-9.
Score: 0.137
-
Transmembrane signaling by G protein-coupled receptors. Methods Mol Biol. 2006; 332:3-49.
Score: 0.132
-
The origins of diversity and specificity in g protein-coupled receptor signaling. J Pharmacol Exp Ther. 2005 Aug; 314(2):485-94.
Score: 0.125
-
Signaling in time and space: G protein-coupled receptors and mitogen-activated protein kinases. Assay Drug Dev Technol. 2003 Apr; 1(2):327-38.
Score: 0.109
-
The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation. J Biol Chem. 2003 Feb 21; 278(8):6258-67.
Score: 0.107
-
The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. J Cell Sci. 2002 Feb 01; 115(Pt 3):455-65.
Score: 0.101
-
Aging-related modifications to G protein-coupled receptor signaling diversity. Pharmacol Ther. 2021 07; 223:107793.
Score: 0.093
-
?-Arrestin2 is a critical component of the GPCR-eNOS signalosome. Proc Natl Acad Sci U S A. 2020 05 26; 117(21):11483-11492.
Score: 0.089
-
Regulation of tyrosine kinase cascades by G-protein-coupled receptors. Curr Opin Cell Biol. 1999 Apr; 11(2):177-83.
Score: 0.083
-
The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling. Pharmacol Rev. 2017 07; 69(3):256-297.
Score: 0.073
-
GPCR Signaling Rides a Wave of Conformational Changes. Cell. 2016 Oct 20; 167(3):602-603.
Score: 0.070
-
Exploring G protein-coupled receptor signaling networks using SILAC-based phosphoproteomics. Methods. 2016 Jan 01; 92:36-50.
Score: 0.064
-
Effect of cellular expression of pleckstrin homology domains on Gi-coupled receptor signaling. J Biol Chem. 1995 Jun 02; 270(22):12984-9.
Score: 0.063
-
Delineation of a conserved arrestin-biased signaling repertoire in vivo. Mol Pharmacol. 2015 Apr; 87(4):706-17.
Score: 0.062
-
Arrestin-dependent activation of ERK and Src family kinases. Handb Exp Pharmacol. 2014; 219:225-57.
Score: 0.058
-
Antagonism of catecholamine receptor signaling by expression of cytoplasmic domains of the receptors. Science. 1993 Mar 05; 259(5100):1453-7.
Score: 0.054
-
Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity. Methods Enzymol. 2013; 522:229-62.
Score: 0.054
-
Arrestins as regulators of kinases and phosphatases. Prog Mol Biol Transl Sci. 2013; 118:115-47.
Score: 0.054
-
Preface. The molecular biology of arrestins. Prog Mol Biol Transl Sci. 2013; 118:xv.
Score: 0.054
-
Functional signaling biases in G protein-coupled receptors: Game Theory and receptor dynamics. Mini Rev Med Chem. 2012 Aug; 12(9):831-40.
Score: 0.052
-
Phospholipase C and protein kinase C-? 2 mediate insulin-like growth factor II-dependent sphingosine kinase 1 activation. Mol Endocrinol. 2011 Dec; 25(12):2144-56.
Score: 0.049
-
Brave new world? Arrestin pathway bias in drug design. Endocr Metab Immune Disord Drug Targets. 2011 Jun; 11(2):90-1.
Score: 0.048
-
Refining efficacy: allosterism and bias in G protein-coupled receptor signaling. Methods Mol Biol. 2011; 756:3-35.
Score: 0.047
-
A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation. Sci Transl Med. 2009 Oct 07; 1(1):1ra1.
Score: 0.043
-
Essential role of c-Cbl in amphiregulin-induced recycling and signaling of the endogenous epidermal growth factor receptor. Biochemistry. 2009 Feb 24; 48(7):1462-73.
Score: 0.041
-
The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth. Biochemistry. 2008 Nov 04; 47(44):11682-92.
Score: 0.040
-
Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors. J Biol Chem. 2006 Oct 20; 281(42):31399-407.
Score: 0.035
-
Constitutive ERK1/2 activation by a chimeric neurokinin 1 receptor-beta-arrestin1 fusion protein. Probing the composition and function of the G protein-coupled receptor "signalsome". J Biol Chem. 2006 Jul 14; 281(28):19346-57.
Score: 0.034
-
beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts. J Biol Chem. 2005 Sep 16; 280(37):32157-67.
Score: 0.032
-
Composition and function of g protein-coupled receptor signalsomes controlling mitogen-activated protein kinase activity. J Mol Neurosci. 2005; 26(2-3):253-64.
Score: 0.031
-
Not so strange bedfellows: G-protein-coupled receptors and Src family kinases. Oncogene. 2004 Oct 18; 23(48):7969-78.
Score: 0.030
-
Transactivation of the epidermal growth factor receptor mediates parathyroid hormone and prostaglandin F2 alpha-stimulated mitogen-activated protein kinase activation in cultured transgenic murine osteoblasts. Mol Endocrinol. 2003 Aug; 17(8):1607-21.
Score: 0.027
-
Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus. J Biol Chem. 2002 Aug 09; 277(32):28631-40.
Score: 0.026
-
SnapShot: ?-Arrestin Functions. Cell. 2020 09 03; 182(5):1362-1362.e1.
Score: 0.023
-
Transactivation of the EGF receptor mediates IGF-1-stimulated shc phosphorylation and ERK1/2 activation in COS-7 cells. J Biol Chem. 2000 Jul 21; 275(29):22583-9.
Score: 0.023
-
Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between ?-Arrestin Isoforms. Cell Rep. 2019 09 24; 28(13):3287-3299.e6.
Score: 0.021
-
Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science. 1999 Jan 29; 283(5402):655-61.
Score: 0.020
-
Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling. J Biol Chem. 1999 Jan 15; 274(3):1185-8.
Score: 0.020
-
Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation. J Biol Chem. 1997 Feb 14; 272(7):4637-44.
Score: 0.018
-
Mitogenic signaling via G protein-coupled receptors. Endocr Rev. 1996 Dec; 17(6):698-714.
Score: 0.018
-
S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization. J Lipid Res. 2017 02; 58(2):325-338.
Score: 0.018
-
Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases. J Biol Chem. 1996 Aug 09; 271(32):19443-50.
Score: 0.017
-
Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway. J Biol Chem. 1996 May 24; 271(21):12133-6.
Score: 0.017
-
Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway. Nature. 1995 Aug 31; 376(6543):781-4.
Score: 0.016
-
Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na+/H+ exchanger. Am J Physiol Cell Physiol. 2014 Sep 15; 307(6):C554-60.
Score: 0.015
-
Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling. J Biol Chem. 1994 Feb 25; 269(8):6193-7.
Score: 0.015
-
The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers. J Biol Chem. 2013 Jun 28; 288(26):18872-84.
Score: 0.014
-
A pertussis toxin-sensitive G-protein mediates some aspects of insulin action in BC3H-1 murine myocytes. J Biol Chem. 1990 Oct 05; 265(28):16873-9.
Score: 0.011
-
Bradykinin decreases podocyte permeability through ADAM17-dependent epidermal growth factor receptor activation and zonula occludens-1 rearrangement. J Pharmacol Exp Ther. 2010 Sep 01; 334(3):775-83.
Score: 0.011
-
HDL3, but not HDL2, stimulates plasminogen activator inhibitor-1 release from adipocytes: the role of sphingosine-1-phosphate. J Lipid Res. 2010 Sep; 51(9):2619-28.
Score: 0.011
-
Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation. J Biol Chem. 2007 Oct 05; 282(40):29549-62.
Score: 0.009
-
Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression. Mol Immunol. 2007 May; 44(12):3092-9.
Score: 0.009
-
Identification of a putative nuclear localization sequence within ANG II AT(1A) receptor associated with nuclear activation. Am J Physiol Cell Physiol. 2007 Apr; 292(4):C1398-408.
Score: 0.009
-
Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation. J Biol Chem. 2006 Apr 21; 281(16):10856-64.
Score: 0.008
-
Arrestin-mediated ERK activation by gonadotropin-releasing hormone receptors: receptor-specific activation mechanisms and compartmentalization. J Biol Chem. 2006 Feb 03; 281(5):2701-10.
Score: 0.008
-
Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: a functional role for receptor-receptor interaction in vivo. Circulation. 2003 Sep 30; 108(13):1611-8.
Score: 0.007
-
beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport. J Biol Chem. 2001 Nov 23; 276(47):43663-7.
Score: 0.006
-
Mitogenic signaling in androgen sensitive and insensitive prostate cancer cell lines. J Urol. 2000 Mar; 163(3):1027-32.
Score: 0.006
-
Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science. 1998 Apr 24; 280(5363):574-7.
Score: 0.005
-
Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. J Biol Chem. 1998 Jan 09; 273(2):685-8.
Score: 0.005
-
G-protein-coupled receptors and their regulation: activation of the MAP kinase signaling pathway by G-protein-coupled receptors. Adv Second Messenger Phosphoprotein Res. 1997; 31:263-77.
Score: 0.004
-
G(o)-protein alpha-subunits activate mitogen-activated protein kinase via a novel protein kinase C-dependent mechanism. J Biol Chem. 1996 Jan 19; 271(3):1266-9.
Score: 0.004
-
Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase. Proc Natl Acad Sci U S A. 1994 Apr 26; 91(9):3637-41.
Score: 0.004