Louis Luttrell to Humans
This is a "connection" page, showing publications Louis Luttrell has written about Humans.
Connection Strength
0.825
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Manifold roles of ?-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9. Sci Signal. 2018 09 25; 11(549).
Score: 0.024
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The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling. Pharmacol Rev. 2017 07; 69(3):256-297.
Score: 0.022
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Translating in vitro ligand bias into in vivo efficacy. Cell Signal. 2018 01; 41:46-55.
Score: 0.022
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GPCR Signaling Rides a Wave of Conformational Changes. Cell. 2016 Oct 20; 167(3):602-603.
Score: 0.021
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Hyperparathyroidism-jaw Tumor Syndrome: An Overlooked Cause of Severe Hypercalcemia. Am J Med Sci. 2016 Sep; 352(3):302-5.
Score: 0.020
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The conformational signature of ?-arrestin2 predicts its trafficking and signalling functions. Nature. 2016 Mar 31; 531(7596):665-8.
Score: 0.020
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Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism. Mol Pharmacol. 2015 Sep; 88(3):579-88.
Score: 0.019
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Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation. Methods. 2016 Jan 01; 92:51-63.
Score: 0.019
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Delineation of a conserved arrestin-biased signaling repertoire in vivo. Mol Pharmacol. 2015 Apr; 87(4):706-17.
Score: 0.019
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Arrestin-dependent angiotensin AT1 receptor signaling regulates Akt and mTor-mediated protein synthesis. J Biol Chem. 2014 Sep 19; 289(38):26155-26166.
Score: 0.018
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Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery. Mol Endocrinol. 2014 Mar; 28(3):281-94.
Score: 0.017
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Arrestin-dependent activation of ERK and Src family kinases. Handb Exp Pharmacol. 2014; 219:225-57.
Score: 0.017
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Emergent biological properties of arrestin pathway-selective biased agonism. J Recept Signal Transduct Res. 2013 Jun; 33(3):153-61.
Score: 0.016
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Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity. Methods Enzymol. 2013; 522:229-62.
Score: 0.016
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Arrestins as regulators of kinases and phosphatases. Prog Mol Biol Transl Sci. 2013; 118:115-47.
Score: 0.016
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Arrestin pathways as drug targets. Prog Mol Biol Transl Sci. 2013; 118:469-97.
Score: 0.016
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Preface. The molecular biology of arrestins. Prog Mol Biol Transl Sci. 2013; 118:xv.
Score: 0.016
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Phospholipase C and protein kinase C-? 2 mediate insulin-like growth factor II-dependent sphingosine kinase 1 activation. Mol Endocrinol. 2011 Dec; 25(12):2144-56.
Score: 0.015
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'Biasing' the parathyroid hormone receptor: a novel anabolic approach to increasing bone mass? Br J Pharmacol. 2011 Sep; 164(1):59-67.
Score: 0.015
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Brave new world? Arrestin pathway bias in drug design. Endocr Metab Immune Disord Drug Targets. 2011 Jun; 11(2):90-1.
Score: 0.014
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The beta-arrestin pathway-selective type 1A angiotensin receptor (AT1A) agonist [Sar1,Ile4,Ile8]angiotensin II regulates a robust G protein-independent signaling network. J Biol Chem. 2011 Jun 03; 286(22):19880-91.
Score: 0.014
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Refining efficacy: allosterism and bias in G protein-coupled receptor signaling. Methods Mol Biol. 2011; 756:3-35.
Score: 0.014
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Refining efficacy: exploiting functional selectivity for drug discovery. Adv Pharmacol. 2011; 62:79-107.
Score: 0.014
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Beyond desensitization: physiological relevance of arrestin-dependent signaling. Pharmacol Rev. 2010 Jun; 62(2):305-30.
Score: 0.013
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Diversity in arrestin function. Cell Mol Life Sci. 2009 Sep; 66(18):2953-73.
Score: 0.013
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Insulin-like growth factor-2/mannose-6 phosphate receptors. Vitam Horm. 2009; 80:667-97.
Score: 0.012
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The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth. Biochemistry. 2008 Nov 04; 47(44):11682-92.
Score: 0.012
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Heptahelical terpsichory. Who calls the tune? J Recept Signal Transduct Res. 2008; 28(1-2):39-58.
Score: 0.011
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Role of beta-arrestin-mediated desensitization and signaling in the control of angiotensin AT1a receptor-stimulated transcription. J Biol Chem. 2008 Jan 25; 283(4):2088-97.
Score: 0.011
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The insulin-like growth factor type 1 and insulin-like growth factor type 2/mannose-6-phosphate receptors independently regulate ERK1/2 activity in HEK293 cells. J Biol Chem. 2007 Sep 07; 282(36):26150-7.
Score: 0.011
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G protein-coupled receptor signaling complexity in neuronal tissue: implications for novel therapeutics. Curr Alzheimer Res. 2007 Feb; 4(1):3-19.
Score: 0.011
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Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors. J Biol Chem. 2006 Oct 20; 281(42):31399-407.
Score: 0.010
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Signal switching, crosstalk, and arrestin scaffolds: novel G protein-coupled receptor signaling in cardiovascular disease. Hypertension. 2006 Aug; 48(2):173-9.
Score: 0.010
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Constitutive ERK1/2 activation by a chimeric neurokinin 1 receptor-beta-arrestin1 fusion protein. Probing the composition and function of the G protein-coupled receptor "signalsome". J Biol Chem. 2006 Jul 14; 281(28):19346-57.
Score: 0.010
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Transmembrane signaling by G protein-coupled receptors. Methods Mol Biol. 2006; 332:3-49.
Score: 0.010
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beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts. J Biol Chem. 2005 Sep 16; 280(37):32157-67.
Score: 0.010
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The origins of diversity and specificity in g protein-coupled receptor signaling. J Pharmacol Exp Ther. 2005 Aug; 314(2):485-94.
Score: 0.009
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Composition and function of g protein-coupled receptor signalsomes controlling mitogen-activated protein kinase activity. J Mol Neurosci. 2005; 26(2-3):253-64.
Score: 0.009
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Not so strange bedfellows: G-protein-coupled receptors and Src family kinases. Oncogene. 2004 Oct 18; 23(48):7969-78.
Score: 0.009
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Ectodomain shedding-dependent transactivation of epidermal growth factor receptors in response to insulin-like growth factor type I. Mol Endocrinol. 2004 Nov; 18(11):2727-39.
Score: 0.009
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Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus. J Biol Chem. 2002 Aug 09; 277(32):28631-40.
Score: 0.008
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Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2449-54.
Score: 0.007
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Aging-related modifications to G protein-coupled receptor signaling diversity. Pharmacol Ther. 2021 07; 223:107793.
Score: 0.007
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Reply to Schierwagen et al.: ?-Arrestins in liver disease. Proc Natl Acad Sci U S A. 2020 11 03; 117(44):27085-27086.
Score: 0.007
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Longitudinal Plasma Kallikrein Levels and Their Association With the Risk of Cardiovascular Disease Outcomes in Type 1 Diabetes in DCCT/EDIC. Diabetes. 2020 11; 69(11):2440-2445.
Score: 0.007
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Pasteurella multocida toxin stimulates mitogen-activated protein kinase via G(q/11)-dependent transactivation of the epidermal growth factor receptor. J Biol Chem. 2000 Jan 21; 275(3):2239-45.
Score: 0.007
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Islet Harvest in Carbon Monoxide-Saturated Medium for Chronic Pancreatitis Patients Undergoing Islet Autotransplantation. Cell Transplant. 2019 Dec; 28(1_suppl):25S-36S.
Score: 0.007
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Activation of extracellular signal-regulated kinase in human prostate cancer. J Urol. 1999 Oct; 162(4):1537-42.
Score: 0.006
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Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between ?-Arrestin Isoforms. Cell Rep. 2019 09 24; 28(13):3287-3299.e6.
Score: 0.006
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Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases. J Biol Chem. 1999 May 14; 274(20):13978-84.
Score: 0.006
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Probing Arrestin Function Using Intramolecular FlAsH-BRET Biosensors. Methods Mol Biol. 2019; 1957:309-322.
Score: 0.006
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Analysis of longitudinal semicontinuous data using marginalized two-part model. J Transl Med. 2018 11 06; 16(1):301.
Score: 0.006
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GIT2-A keystone in ageing and age-related disease. Ageing Res Rev. 2018 May; 43:46-63.
Score: 0.006
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Plasma Connective Tissue Growth Factor (CTGF/CCN2) Levels Predict Myocardial Infarction in the Veterans Affairs Diabetes Trial (VADT) Cohort. Diabetes Care. 2018 04; 41(4):840-846.
Score: 0.006
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Autologous Mesenchymal Stem Cell and Islet Cotransplantation: Safety and Efficacy. Stem Cells Transl Med. 2018 01; 7(1):11-19.
Score: 0.006
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Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation. J Biol Chem. 1997 Feb 14; 272(7):4637-44.
Score: 0.005
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S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization. J Lipid Res. 2017 02; 58(2):325-338.
Score: 0.005
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Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases. J Biol Chem. 1996 Aug 09; 271(32):19443-50.
Score: 0.005
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Angiotensin II receptors and peritoneal dialysis-induced peritoneal fibrosis. Int J Biochem Cell Biol. 2016 08; 77(Pt B):240-50.
Score: 0.005
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Plasma Prekallikrein Is Associated With Carotid Intima-Media Thickness in Type 1 Diabetes. Diabetes. 2016 Feb; 65(2):498-502.
Score: 0.005
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Inhibition of Sphingosine Kinase 1 Ameliorates Angiotensin II-Induced Hypertension and Inhibits Transmembrane Calcium Entry via Store-Operated Calcium Channel. Mol Endocrinol. 2015 Jun; 29(6):896-908.
Score: 0.005
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Mycoplasma hominis septic arthritis: two case reports and review. Clin Infect Dis. 1994 Dec; 19(6):1067-70.
Score: 0.005
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Novel mechanism of plasma prekallikrein (PK) activation by vascular smooth muscle cells: evidence of the presence of PK activator. J Biol Regul Homeost Agents. 2014 Oct-Dec; 28(4):587-603.
Score: 0.005
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The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers. J Biol Chem. 2013 Jun 28; 288(26):18872-84.
Score: 0.004
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Textrous!: extracting semantic textual meaning from gene sets. PLoS One. 2013; 8(4):e62665.
Score: 0.004
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Angiotensin II activates NF-?B through AT1A receptor recruitment of ?-arrestin in cultured rat vascular smooth muscle cells. Am J Physiol Cell Physiol. 2013 Jun 15; 304(12):C1176-86.
Score: 0.004
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Relationship between vitamin D status and incidence of vascular events in the Veterans Affairs Diabetes Trial. Atherosclerosis. 2013 Jun; 228(2):502-7.
Score: 0.004
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Antagonism of catecholamine receptor signaling by expression of cytoplasmic domains of the receptors. Science. 1993 Mar 05; 259(5100):1453-7.
Score: 0.004
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A high-content, live-cell, and real-time approach to the quantitation of ligand-induced ?-Arrestin2 and Class A/Class B GPCR mobilization. Microsc Microanal. 2013 Feb; 19(1):150-70.
Score: 0.004
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Functional signaling biases in G protein-coupled receptors: Game Theory and receptor dynamics. Mini Rev Med Chem. 2012 Aug; 12(9):831-40.
Score: 0.004
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Low-density lipoprotein induced expression of connective tissue growth factor via transactivation of sphingosine 1-phosphate receptors in mesangial cells. Mol Endocrinol. 2012 May; 26(5):833-45.
Score: 0.004
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Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation. Mol Immunol. 2011 Oct; 49(1-2):64-74.
Score: 0.004
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Plasma kallikrein promotes epidermal growth factor receptor transactivation and signaling in vascular smooth muscle through direct activation of protease-activated receptors. J Biol Chem. 2010 Nov 05; 285(45):35206-15.
Score: 0.003
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Novel mechanisms in the regulation of G protein-coupled receptor trafficking to the plasma membrane. J Biol Chem. 2010 Oct 29; 285(44):33816-25.
Score: 0.003
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HDL3, but not HDL2, stimulates plasminogen activator inhibitor-1 release from adipocytes: the role of sphingosine-1-phosphate. J Lipid Res. 2010 Sep; 51(9):2619-28.
Score: 0.003
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Genetic variant in the promoter of connective tissue growth factor gene confers susceptibility to nephropathy in type 1 diabetes. J Med Genet. 2010 Jun; 47(6):391-7.
Score: 0.003
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Allosteric modulators of g protein-coupled receptors: future therapeutics for complex physiological disorders. J Pharmacol Exp Ther. 2009 Nov; 331(2):340-8.
Score: 0.003
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Angiotensin II-induced cyclooxygenase 2 expression in rat aorta vascular smooth muscle cells does not require heterotrimeric G protein activation. J Pharmacol Exp Ther. 2009 Jul; 330(1):118-24.
Score: 0.003
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Essential role of c-Cbl in amphiregulin-induced recycling and signaling of the endogenous epidermal growth factor receptor. Biochemistry. 2009 Feb 24; 48(7):1462-73.
Score: 0.003
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c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway. Cell Signal. 2009 Jan; 21(1):103-10.
Score: 0.003
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Connective tissue growth factor and susceptibility to renal and vascular disease risk in type 1 diabetes. J Clin Endocrinol Metab. 2008 May; 93(5):1893-900.
Score: 0.003
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Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation. J Biol Chem. 2007 Oct 05; 282(40):29549-62.
Score: 0.003
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Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression. Mol Immunol. 2007 May; 44(12):3092-9.
Score: 0.003
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Identification of a putative nuclear localization sequence within ANG II AT(1A) receptor associated with nuclear activation. Am J Physiol Cell Physiol. 2007 Apr; 292(4):C1398-408.
Score: 0.003
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Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation. J Biol Chem. 2006 Apr 21; 281(16):10856-64.
Score: 0.002
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Arrestin-mediated ERK activation by gonadotropin-releasing hormone receptors: receptor-specific activation mechanisms and compartmentalization. J Biol Chem. 2006 Feb 03; 281(5):2701-10.
Score: 0.002
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Beta-arrestin- and G protein receptor kinase-mediated calcium-sensing receptor desensitization. Mol Endocrinol. 2005 Apr; 19(4):1078-87.
Score: 0.002
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Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: a functional role for receptor-receptor interaction in vivo. Circulation. 2003 Sep 30; 108(13):1611-8.
Score: 0.002
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Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2. Proc Natl Acad Sci U S A. 2003 Sep 16; 100(19):10782-7.
Score: 0.002
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Protein kinase A and G protein-coupled receptor kinase phosphorylation mediates beta-1 adrenergic receptor endocytosis through different pathways. J Biol Chem. 2003 Sep 12; 278(37):35403-11.
Score: 0.002
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beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis. J Biol Chem. 2000 Apr 14; 275(15):11312-9.
Score: 0.002
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Mitogenic signaling in androgen sensitive and insensitive prostate cancer cell lines. J Urol. 2000 Mar; 163(3):1027-32.
Score: 0.002
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Feedback regulation of beta-arrestin1 function by extracellular signal-regulated kinases. J Biol Chem. 1999 Jun 04; 274(23):15971-4.
Score: 0.002
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The beta3-adrenergic receptor activates mitogen-activated protein kinase in adipocytes through a Gi-dependent mechanism. J Biol Chem. 1999 Apr 23; 274(17):12017-22.
Score: 0.002
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Serotonin 5-HT1A receptor-mediated Erk activation requires calcium/calmodulin-dependent receptor endocytosis. J Biol Chem. 1999 Feb 19; 274(8):4749-53.
Score: 0.002
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Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science. 1999 Jan 29; 283(5402):655-61.
Score: 0.002
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Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling. J Biol Chem. 1999 Jan 15; 274(3):1185-8.
Score: 0.002
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Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase. J Biol Chem. 1998 Jan 09; 273(2):685-8.
Score: 0.001
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G-protein-coupled receptors and their regulation: activation of the MAP kinase signaling pathway by G-protein-coupled receptors. Adv Second Messenger Phosphoprotein Res. 1997; 31:263-77.
Score: 0.001
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Mitogenic signaling via G protein-coupled receptors. Endocr Rev. 1996 Dec; 17(6):698-714.
Score: 0.001
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Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor. J Biol Chem. 1994 Jun 03; 269(22):15776-85.
Score: 0.001
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Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase. Proc Natl Acad Sci U S A. 1994 Apr 26; 91(9):3637-41.
Score: 0.001