Connection

Besim Ogretmen to Drug Resistance, Neoplasm

This is a "connection" page, showing publications Besim Ogretmen has written about Drug Resistance, Neoplasm.
Connection Strength

1.657
  1. Targeting FLT3-ITD signaling mediates ceramide-dependent mitophagy and attenuates drug resistance in AML. Blood. 2016 10 13; 128(15):1944-1958.
    View in: PubMed
    Score: 0.460
  2. Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A. Blood. 2011 Jun 02; 117(22):5941-52.
    View in: PubMed
    Score: 0.318
  3. Alterations of ceramide/sphingosine 1-phosphate rheostat involved in the regulation of resistance to imatinib-induced apoptosis in K562 human chronic myeloid leukemia cells. J Biol Chem. 2007 Apr 13; 282(15):10922-34.
    View in: PubMed
    Score: 0.238
  4. Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma. Nat Commun. 2019 03 21; 10(1):1296.
    View in: PubMed
    Score: 0.138
  5. Negative regulation of MDR1 promoter activity in MCF-7, but not in multidrug resistant MCF-7/Adr, cells by cross-coupled NF-kappa B/p65 and c-Fos transcription factors and their interaction with the CAAT region. Biochemistry. 1999 Feb 16; 38(7):2189-99.
    View in: PubMed
    Score: 0.137
  6. Molecular mechanisms of loss of beta 2-microglobulin expression in drug-resistant breast cancer sublines and its involvement in drug resistance. Biochemistry. 1998 Aug 18; 37(33):11679-91.
    View in: PubMed
    Score: 0.132
  7. Sphingolipid metabolism in cancer signalling and therapy. Nat Rev Cancer. 2018 Jan; 18(1):33-50.
    View in: PubMed
    Score: 0.125
  8. Proteinase-3, a serine protease which mediates doxorubicin-induced apoptosis in the HL-60 leukemia cell line, is downregulated in its doxorubicin-resistant variant. Oncogene. 2002 Aug 01; 21(33):5160-74.
    View in: PubMed
    Score: 0.043
  9. Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer. J Biol Chem. 2022 02; 298(2):101492.
    View in: PubMed
    Score: 0.042
  10. PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells. J Clin Invest. 2013 Oct; 123(10):4144-57.
    View in: PubMed
    Score: 0.023
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.