Kumar Sambamurti to Aspartic Acid Endopeptidases
This is a "connection" page, showing publications Kumar Sambamurti has written about Aspartic Acid Endopeptidases.
Connection Strength
1.481
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Beta-secretase: structure, function, and evolution. CNS Neurol Disord Drug Targets. 2008 Jun; 7(3):278-94.
Score: 0.322
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Beta-secretase processing of the Alzheimer's amyloid protein precursor (APP). J Mol Neurosci. 2003; 20(3):233-9.
Score: 0.221
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Lipid rafts play an important role in A beta biogenesis by regulating the beta-secretase pathway. J Mol Neurosci. 2002 Aug-Oct; 19(1-2):31-5.
Score: 0.215
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Evidence of a novel mechanism for partial ?-secretase inhibition induced paradoxical increase in secreted amyloid ? protein. PLoS One. 2014; 9(3):e91531.
Score: 0.120
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Taking down the unindicted co-conspirators of amyloid beta-peptide-mediated neuronal death: shared gene regulation of BACE1 and APP genes interacting with CREB, Fe65 and YY1 transcription factors. Curr Alzheimer Res. 2006 Dec; 3(5):475-83.
Score: 0.073
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A partial failure of membrane protein turnover may cause Alzheimer's disease: a new hypothesis. Curr Alzheimer Res. 2006 Feb; 3(1):81-90.
Score: 0.068
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Gene structure and organization of the human beta-secretase (BACE) promoter. FASEB J. 2004 Jun; 18(9):1034-6.
Score: 0.060
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Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization. J Mol Neurosci. 2004; 24(1):137-43.
Score: 0.059
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APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity. Biochem Biophys Res Commun. 2003 Jun 06; 305(3):502-9.
Score: 0.057
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Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme. J Biol Chem. 2003 Jan 24; 278(4):2081-4.
Score: 0.055
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Characterization of recombinant, soluble beta-secretase from an insect cell expression system. Mol Pharmacol. 2001 Mar; 59(3):619-26.
Score: 0.049
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Rivastigmine modifies the a-secretase pathway and potentially early Alzheimer's disease. Transl Psychiatry. 2020 02 03; 10(1):47.
Score: 0.045
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Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein. J Biol Chem. 1999 Sep 17; 274(38):26810-4.
Score: 0.044
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The secretion of amyloid beta-peptides is inhibited in the tacrine-treated human neuroblastoma cells. Brain Res Mol Brain Res. 1998 Nov 20; 62(2):131-40.
Score: 0.042
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High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice. J Neurochem. 2008 Jul; 106(1):475-85.
Score: 0.020
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Functional characterization of the 5' flanking region of the BACE gene: identification of a 91 bp fragment involved in basal level of BACE promoter expression. FASEB J. 2004 Jun; 18(9):1037-9.
Score: 0.015
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Evidence that secretase cleavage of cell surface Alzheimer amyloid precursor occurs after normal endocytic internalization. J Neurosci Res. 1995 Apr 01; 40(5):694-706.
Score: 0.008
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Cellular processing and proteoglycan nature of amyloid precursor proteins. Ann N Y Acad Sci. 1993 Sep 24; 695:132-8.
Score: 0.007