Kumar Sambamurti to Presenilin-1
This is a "connection" page, showing publications Kumar Sambamurti has written about Presenilin-1.
Connection Strength
0.518
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Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer's disease. Curr Alzheimer Res. 2015; 12(1):32-46.
Score: 0.123
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Major carboxyl terminal fragments generated by ?-secretase processing of the Alzheimer amyloid precursor are 50 and 51 amino acids long. Am J Geriatr Psychiatry. 2013 May; 21(5):474-83.
Score: 0.109
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The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice. FASEB J. 2012 Jul; 26(7):2899-910.
Score: 0.101
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A partial failure of membrane protein turnover may cause Alzheimer's disease: a new hypothesis. Curr Alzheimer Res. 2006 Feb; 3(1):81-90.
Score: 0.066
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APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity. Biochem Biophys Res Commun. 2003 Jun 06; 305(3):502-9.
Score: 0.055
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Evidence for lymphatic A? clearance in Alzheimer's transgenic mice. Neurobiol Dis. 2014 Nov; 71:215-9.
Score: 0.030
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Vitamin D3-enriched diet correlates with a decrease of amyloid plaques in the brain of A?PP transgenic mice. J Alzheimers Dis. 2011; 25(2):295-307.
Score: 0.023
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Antisense-induced reduction of presenilin 1 expression selectively increases the production of amyloid beta42 in transfected cells. J Neurochem. 1999 Dec; 73(6):2383-8.
Score: 0.011