Kumar Sambamurti to Stereoisomerism
This is a "connection" page, showing publications Kumar Sambamurti has written about Stereoisomerism.
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0.060
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Synthesis of the Alzheimer drug Posiphen into its primary metabolic products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their inhibition of amyloid precursor protein, a-Synuclein synthesis, interleukin-1? release, and cholinergic action. Antiinflamm Antiallergy Agents Med Chem. 2013; 12(2):117-28.
Score: 0.026
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The experimental Alzheimer's disease drug posiphen [(+)-phenserine] lowers amyloid-beta peptide levels in cell culture and mice. J Pharmacol Exp Ther. 2007 Jan; 320(1):386-96.
Score: 0.017
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Identification of novel small molecule inhibitors of amyloid precursor protein synthesis as a route to lower Alzheimer's disease amyloid-beta peptide. J Pharmacol Exp Ther. 2006 Aug; 318(2):855-62.
Score: 0.017