Avtar Singh to Animals
This is a "connection" page, showing publications Avtar Singh has written about Animals.
Connection Strength
1.406
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Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity. BMC Neurosci. 2018 08 13; 19(1):50.
Score: 0.047
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Combined treatment with GSNO and CAPE accelerates functional recovery via additive antioxidant activities in a mouse model of TBI. J Neurosci Res. 2018 12; 96(12):1900-1913.
Score: 0.046
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Pathology of nNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer's Disease. Neuroscience. 2018 08 01; 384:41-53.
Score: 0.046
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GSNO promotes functional recovery in experimental TBI by stabilizing HIF-1a. Behav Brain Res. 2018 03 15; 340:63-70.
Score: 0.041
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Targeting the nNOS/peroxynitrite/calpain system to confer neuroprotection and aid functional recovery in a mouse model of TBI. Brain Res. 2016 Jan 01; 1630:159-70.
Score: 0.039
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S-nitrosoglutathione reduces tau hyper-phosphorylation and provides neuroprotection in rat model of chronic cerebral hypoperfusion. Brain Res. 2015 Oct 22; 1624:359-369.
Score: 0.038
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Promoting endothelial function by S-nitrosoglutathione through the HIF-1a/VEGF pathway stimulates neurorepair and functional recovery following experimental stroke in rats. Drug Des Devel Ther. 2015; 9:2233-47.
Score: 0.037
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Role of S-nitrosoglutathione mediated mechanisms in tau hyper-phosphorylation. Biochem Biophys Res Commun. 2015 Feb 27; 458(1):214-9.
Score: 0.036
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Effect of vitamin D3 intake on the onset of disease in a murine model of human Krabbe disease. J Neurosci Res. 2015 Jan; 93(1):28-42.
Score: 0.036
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Role of endogenous psychosine accumulation in oligodendrocyte differentiation and survival: implication for Krabbe disease. Brain Res. 2013 May 01; 1508:44-52.
Score: 0.032
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Protective role of S-nitrosoglutathione (GSNO) against cognitive impairment in rat model of chronic cerebral hypoperfusion. J Alzheimers Dis. 2013; 34(3):621-35.
Score: 0.032
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Stimulation of functional recovery via the mechanisms of neurorepair by S-nitrosoglutathione and motor exercise in a rat model of transient cerebral ischemia and reperfusion. Restor Neurol Neurosci. 2012; 30(5):383-96.
Score: 0.029
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Factors that affect postnatal bone growth retardation in the twitcher murine model of Krabbe disease. Biochim Biophys Acta. 2010 Jul-Aug; 1802(7-8):601-8.
Score: 0.026
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Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis. Glia. 2009 Jan 15; 57(2):182-93.
Score: 0.024
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Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis. Exp Neurol. 2008 Dec; 214(2):168-80.
Score: 0.023
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Psychosine-induced alterations in peroxisomes of twitcher mouse liver. Arch Biochem Biophys. 2008 Sep 15; 477(2):211-8.
Score: 0.023
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The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe disease. J Neurochem. 2008 Jun; 105(5):1820-33.
Score: 0.022
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Modulation of peroxisome proliferator-activated receptor-alpha activity by N-acetyl cysteine attenuates inhibition of oligodendrocyte development in lipopolysaccharide stimulated mixed glial cultures. J Neurochem. 2008 May; 105(3):956-70.
Score: 0.022
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Lipopolysaccharide-induced peroxisomal dysfunction exacerbates cerebral white matter injury: attenuation by N-acetyl cysteine. Exp Neurol. 2008 Apr; 210(2):560-76.
Score: 0.022
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Caffeic acid phenethyl ester reduces neurovascular inflammation and protects rat brain following transient focal cerebral ischemia. J Neurochem. 2007 Jul; 102(2):365-77.
Score: 0.021
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Post-trauma Lipitor treatment prevents endothelial dysfunction, facilitates neuroprotection, and promotes locomotor recovery following spinal cord injury. J Neurochem. 2007 Apr; 101(1):182-200.
Score: 0.021
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GSNO attenuates EAE disease by S-nitrosylation-mediated modulation of endothelial-monocyte interactions. Glia. 2007 Jan 01; 55(1):65-77.
Score: 0.021
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Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis. Am J Pathol. 2006 Sep; 169(3):1012-25.
Score: 0.020
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5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside attenuates experimental autoimmune encephalomyelitis via modulation of endothelial-monocyte interaction. J Neurosci Res. 2006 Aug 15; 84(3):614-25.
Score: 0.020
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IL-4-induced peroxisome proliferator-activated receptor gamma activation inhibits NF-kappaB trans activation in central nervous system (CNS) glial cells and protects oligodendrocyte progenitors under neuroinflammatory disease conditions: implication for CNS-demyelinating diseases. J Immunol. 2006 Apr 01; 176(7):4385-98.
Score: 0.020
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Dysfunction of peroxisomes in twitcher mice brain: a possible mechanism of psychosine-induced disease. Biochem Biophys Res Commun. 2006 Apr 28; 343(1):229-38.
Score: 0.020
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Inhibition of phosphoinositide 3 kinase-Akt (protein kinase B)-nuclear factor-kappa B pathway by lovastatin limits endothelial-monocyte cell interaction. J Neurochem. 2005 Jul; 94(1):204-14.
Score: 0.019
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Peroxisomal participation in psychosine-mediated toxicity: implications for Krabbe's disease. J Neurosci Res. 2005 Jun 15; 80(6):845-54.
Score: 0.019
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N-acetylcysteine prevents endotoxin-induced degeneration of oligodendrocyte progenitors and hypomyelination in developing rat brain. J Neurosci Res. 2004 Nov 01; 78(3):347-61.
Score: 0.018
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Attenuation of ischemia-reperfusion injury in a canine model of autologous renal transplantation. Transplantation. 2004 Sep 15; 78(5):654-9.
Score: 0.018
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Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke. J Neurosci Res. 2004 May 15; 76(4):519-27.
Score: 0.017
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The involvement of glucose metabolism in the regulation of inducible nitric oxide synthase gene expression in glial cells: possible role of glucose-6-phosphate dehydrogenase and CCAAT/enhancing binding protein. J Neurosci. 2003 Aug 20; 23(20):7470-8.
Score: 0.017
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N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia. Brain Res. 2003 May 02; 971(1):1-8.
Score: 0.016
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Attenuation of renal ischemia/reperfusion injury by a triple drug combination therapy. J Nephrol. 2003 Jan-Feb; 16(1):63-74.
Score: 0.016
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Combination therapy of N-acetylcysteine, sodium nitroprusside and phosphoramidon attenuates ischemia-reperfusion injury in rat kidney. Mol Cell Biochem. 2002 Nov; 240(1-2):9-17.
Score: 0.016
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Apoptotic positive cells in Krabbe brain and induction of apoptosis in rat C6 glial cells by psychosine. Neurosci Lett. 2002 Sep 20; 330(2):183-7.
Score: 0.015
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Vascular and immunopathological role of Asymmetric Dimethylarginine (ADMA) in Experimental Autoimmune Encephalomyelitis. Immunology. 2021 11; 164(3):602-616.
Score: 0.014
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Regulation of B cell functions by S-nitrosoglutathione in the EAE model. Redox Biol. 2021 09; 45:102053.
Score: 0.014
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GSNOR and ALDH2 alleviate traumatic spinal cord injury. Brain Res. 2021 05 01; 1758:147335.
Score: 0.014
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Detoxification of Reactive Aldehydes by Alda-1 Treatment Ameliorates Experimental Autoimmune Encephalomyelitis in Mice. Neuroscience. 2021 03 15; 458:31-42.
Score: 0.014
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Targeting GSNOR for functional recovery in a middle-aged mouse model of stroke. Brain Res. 2020 08 15; 1741:146879.
Score: 0.013
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Asymmetric dimethylarginine exacerbates cognitive dysfunction associated with cerebrovascular pathology. FASEB J. 2020 05; 34(5):6808-6823.
Score: 0.013
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S-Nitrosoglutathione Mimics the Beneficial Activity of Endothelial Nitric Oxide Synthase-Derived Nitric Oxide in a Mouse Model of Stroke. J Stroke Cerebrovasc Dis. 2019 Dec; 28(12):104470.
Score: 0.013
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Optical Pooled Screens in Human Cells. Cell. 2019 10 17; 179(3):787-799.e17.
Score: 0.013
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Regulation of IL-10 and IL-17 mediated experimental autoimmune encephalomyelitis by S-nitrosoglutathione. Immunobiology. 2018 10; 223(10):549-554.
Score: 0.012
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S-nitrosoglutathione reductase (GSNOR) inhibitor as an immune modulator in experimental autoimmune encephalomyelitis. Free Radic Biol Med. 2018 06; 121:57-68.
Score: 0.011
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Combination therapy of lovastatin and AMP-activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model. Immunology. 2018 07; 154(3):434-451.
Score: 0.011
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Regulation of STAT3 and NF-?B activations by S-nitrosylation in multiple myeloma. Free Radic Biol Med. 2017 05; 106:245-253.
Score: 0.011
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Biochemical, cell biological, pathological, and therapeutic aspects of Krabbe's disease. J Neurosci Res. 2016 11; 94(11):990-1006.
Score: 0.010
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S-Nitrosoglutathione ameliorates acute renal dysfunction in a rat model of lipopolysaccharide-induced sepsis. J Pharm Pharmacol. 2016 Oct; 68(10):1310-9.
Score: 0.010
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STAT3 Regulation By S-Nitrosylation: Implication In Cancer. Redox Biol. 2015 08; 5:416-417.
Score: 0.010
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AKP-11 - A Novel S1P1 Agonist with Favorable Safety Profile Attenuates Experimental Autoimmune Encephalomyelitis in Rat Model of Multiple Sclerosis. PLoS One. 2015; 10(10):e0141781.
Score: 0.010
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Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy. BMC Neurosci. 2015 Jul 15; 16:42.
Score: 0.009
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S-Nitrosoglutathione-mediated STAT3 regulation in efficacy of radiotherapy and cisplatin therapy in head and neck squamous cell carcinoma. Redox Biol. 2015 Dec; 6:41-50.
Score: 0.009
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Oral administration of cytosolic PLA2 inhibitor arachidonyl trifluoromethyl ketone ameliorates cauda equina compression injury in rats. J Neuroinflammation. 2015 May 15; 12:94.
Score: 0.009
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ABCD1 deletion-induced mitochondrial dysfunction is corrected by SAHA: implication for adrenoleukodystrophy. J Neurochem. 2015 May; 133(3):380-96.
Score: 0.009
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S-Nitrosoglutathione protects the spinal bladder: novel therapeutic approach to post-spinal cord injury bladder remodeling. Neurourol Urodyn. 2015 Aug; 34(6):519-26.
Score: 0.009
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STAT3 regulation by S-nitrosylation: implication for inflammatory disease. Antioxid Redox Signal. 2014 Jun 01; 20(16):2514-27.
Score: 0.009
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PPARa activation induces N(e)-Lys-acetylation of rat liver peroxisomal multifunctional enzyme type 1. Lipids. 2014 Feb; 49(2):119-31.
Score: 0.008
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Modulation of Rho-Rock signaling pathway protects oligodendrocytes against cytokine toxicity via PPAR-a-dependent mechanism. Glia. 2013 Sep; 61(9):1500-1517.
Score: 0.008
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AMP-activated protein kinase signaling protects oligodendrocytes that restore central nervous system functions in an experimental autoimmune encephalomyelitis model. Am J Pathol. 2013 Aug; 183(2):526-41.
Score: 0.008
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S-nitrosoglutathione induces ciliary neurotrophic factor expression in astrocytes, which has implications to protect the central nervous system under pathological conditions. J Biol Chem. 2013 Feb 08; 288(6):3831-43.
Score: 0.008
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The inhibitory effect of S-nitrosoglutathione on blood-brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke. J Neurochem. 2012 Nov; 123 Suppl 2:86-97.
Score: 0.008
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Interference with RhoA-ROCK signaling mechanism in autoreactive CD4+ T cells enhances the bioavailability of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis. Am J Pathol. 2012 Sep; 181(3):993-1006.
Score: 0.008
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S-nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats. J Neuroinflammation. 2011 Jul 06; 8:78.
Score: 0.007
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Synergistic activity of interleukin-17 and tumor necrosis factor-a enhances oxidative stress-mediated oligodendrocyte apoptosis. J Neurochem. 2011 Feb; 116(4):508-21.
Score: 0.007
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Activation of PPAR-? and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells. Glia. 2010 Nov 01; 58(14):1669-85.
Score: 0.007
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Involvement of AMP-activated-protein-kinase (AMPK) in neuronal amyloidogenesis. Biochem Biophys Res Commun. 2010 Sep 03; 399(4):487-91.
Score: 0.007
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Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact. J Neuroinflammation. 2009 Nov 04; 6:32.
Score: 0.006
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Reduction of lipoxidative load by secretory phospholipase A2 inhibition protects against neurovascular injury following experimental stroke in rat. J Neuroinflammation. 2009 Aug 13; 6:21.
Score: 0.006
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Peroxisomal dysfunction in inflammatory childhood white matter disorders: an unexpected contributor to neuropathology. J Child Neurol. 2009 Sep; 24(9):1147-57.
Score: 0.006
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Attenuation of lipopolysaccharide-induced inflammatory response and phospholipids metabolism at the feto-maternal interface by N-acetyl cysteine. Pediatr Res. 2008 Oct; 64(4):334-9.
Score: 0.006
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Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death. Neurosci Lett. 2008 Aug 08; 440(3):260-4.
Score: 0.006
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Lovastatin inhibits amyloid precursor protein (APP) beta-cleavage through reduction of APP distribution in Lubrol WX extractable low density lipid rafts. J Neurochem. 2008 May; 105(4):1536-49.
Score: 0.006
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Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis. Mol Pharmacol. 2008 May; 73(5):1381-93.
Score: 0.006
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Lactosylceramide: a lipid second messenger in neuroinflammatory disease. J Neurochem. 2007 Nov; 103 Suppl 1:180-91.
Score: 0.006
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T-bet is essential for the progression of experimental autoimmune encephalomyelitis. Immunology. 2006 Jul; 118(3):384-91.
Score: 0.005
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Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic-ischemic brain injury in neonatal rats. Pediatr Res. 2006 May; 59(5):684-9.
Score: 0.005
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Cerebrovascular protection by various nitric oxide donors in rats after experimental stroke. Nitric Oxide. 2006 Sep; 15(2):114-24.
Score: 0.005
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5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase. J Biol Chem. 2005 Nov 25; 280(47):39582-93.
Score: 0.005
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HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis. FASEB J. 2005 Sep; 19(11):1407-21.
Score: 0.005
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The use of N-acetylcysteine for the prevention of hypertension in the reduced uterine perfusion pressure model for preeclampsia in Sprague-Dawley rats. Am J Obstet Gynecol. 2005 Sep; 193(3 Pt 2):952-6.
Score: 0.005
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Involvement of phospholipase A2 and lipoxygenase in lipopolysaccharide-induced inducible nitric oxide synthase expression in glial cells. Glia. 2005 Jul; 51(1):13-21.
Score: 0.005
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5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis. J Immunol. 2005 Jul 01; 175(1):566-74.
Score: 0.005
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Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats. J Neurosci Res. 2005 Feb 01; 79(3):340-50.
Score: 0.005
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S-Nitrosoglutathione reduces inflammation and protects brain against focal cerebral ischemia in a rat model of experimental stroke. J Cereb Blood Flow Metab. 2005 Feb; 25(2):177-92.
Score: 0.005
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A novel role of lactosylceramide in the regulation of tumor necrosis factor alpha-mediated proliferation of rat primary astrocytes. Implications for astrogliosis following neurotrauma. J Biol Chem. 2005 Apr 08; 280(14):13742-51.
Score: 0.005
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Adenosine kinase inhibitor attenuates the expression of inducible nitric oxide synthase in glial cells. Neuropharmacology. 2005 Jan; 48(1):151-60.
Score: 0.005
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Dual role of cAMP in iNOS expression in glial cells and macrophages is mediated by differential regulation of p38-MAPK/ATF-2 activation and iNOS stability. Free Radic Biol Med. 2004 Dec 01; 37(11):1834-44.
Score: 0.005
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The 15-deoxy-delta12,14-prostaglandin J2 inhibits the inflammatory response in primary rat astrocytes via down-regulating multiple steps in phosphatidylinositol 3-kinase-Akt-NF-kappaB-p300 pathway independent of peroxisome proliferator-activated receptor gamma. J Immunol. 2004 Oct 15; 173(8):5196-208.
Score: 0.004
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Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment. Brain Res. 2004 Oct 01; 1022(1-2):1-11.
Score: 0.004
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Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E. Free Radic Biol Med. 2004 Aug 01; 37(3):325-38.
Score: 0.004
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Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin. J Neurosci Res. 2004 Jul 01; 77(1):63-81.
Score: 0.004
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A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases. J Neurosci. 2004 Jun 30; 24(26):5942-54.
Score: 0.004
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The role of neutral sphingomyelinase produced ceramide in lipopolysaccharide-mediated expression of inducible nitric oxide synthase. J Neurochem. 2004 Feb; 88(3):583-93.
Score: 0.004
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Potential targets of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor for multiple sclerosis therapy. J Immunol. 2004 Jan 15; 172(2):1273-86.
Score: 0.004
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5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase. J Neurosci. 2004 Jan 14; 24(2):479-87.
Score: 0.004
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Rho A negatively regulates cytokine-mediated inducible nitric oxide synthase expression in brain-derived transformed cell lines: negative regulation of IKKalpha. Free Radic Biol Med. 2003 Nov 01; 35(9):1037-50.
Score: 0.004