Inderjit Singh to Humans
This is a "connection" page, showing publications Inderjit Singh has written about Humans.
Connection Strength
0.754
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Vascular and immunopathological role of Asymmetric Dimethylarginine (ADMA) in Experimental Autoimmune Encephalomyelitis. Immunology. 2021 11; 164(3):602-616.
Score: 0.029
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Hypoxia-inducible factor-1 drives divergent immunomodulatory functions in the pathogenesis of autoimmune diseases. Immunology. 2021 09; 164(1):31-42.
Score: 0.029
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Peroxisomal footprint in the pathogenesis of nonalcoholic steatohepatitis. Ann Hepatol. 2020 Sep - Oct; 19(5):466-471.
Score: 0.026
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Combination therapy of lovastatin and AMP-activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model. Immunology. 2018 07; 154(3):434-451.
Score: 0.023
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Biochemical, cell biological, pathological, and therapeutic aspects of Krabbe's disease. J Neurosci Res. 2016 11; 94(11):990-1006.
Score: 0.021
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MicroRNA Profiling Identifies miR-196a as Differentially Expressed in Childhood Adrenoleukodystrophy and Adult Adrenomyeloneuropathy. Mol Neurobiol. 2017 03; 54(2):1392-1403.
Score: 0.020
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STAT3 Regulation By S-Nitrosylation: Implication In Cancer. Redox Biol. 2015 08; 5:416-417.
Score: 0.020
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Functional Characterization of IPSC-Derived Brain Cells as a Model for X-Linked Adrenoleukodystrophy. PLoS One. 2015; 10(11):e0143238.
Score: 0.020
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S-Nitrosoglutathione-mediated STAT3 regulation in efficacy of radiotherapy and cisplatin therapy in head and neck squamous cell carcinoma. Redox Biol. 2015 Dec; 6:41-50.
Score: 0.019
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ABCD1 deletion-induced mitochondrial dysfunction is corrected by SAHA: implication for adrenoleukodystrophy. J Neurochem. 2015 May; 133(3):380-96.
Score: 0.018
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Histone deacetylase inhibitor upregulates peroxisomal fatty acid oxidation and inhibits apoptotic cell death in abcd1-deficient glial cells. PLoS One. 2013; 8(7):e70712.
Score: 0.017
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Caffeic acid phenethyl ester induces adrenoleukodystrophy (Abcd2) gene in human X-ALD fibroblasts and inhibits the proinflammatory response in Abcd1/2 silenced mouse primary astrocytes. Biochim Biophys Acta. 2013 Apr; 1831(4):747-58.
Score: 0.016
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HDAC inhibitor SAHA normalizes the levels of VLCFAs in human skin fibroblasts from X-ALD patients and downregulates the expression of proinflammatory cytokines in Abcd1/2-silenced mouse astrocytes. J Lipid Res. 2011 Nov; 52(11):2056-69.
Score: 0.015
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Pathomechanisms underlying X-adrenoleukodystrophy: a three-hit hypothesis. Brain Pathol. 2010 Jul; 20(4):838-44.
Score: 0.013
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Very long-chain fatty acid accumulation causes lipotoxic response via 5-lipoxygenase in cerebral adrenoleukodystrophy. J Lipid Res. 2010 Jul; 51(7):1685-95.
Score: 0.013
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Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact. J Neuroinflammation. 2009 Nov 04; 6:32.
Score: 0.013
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Neuroprotective interventions: is it too late? J Child Neurol. 2009 Sep; 24(9):1212-9.
Score: 0.013
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Peroxisomal dysfunction in inflammatory childhood white matter disorders: an unexpected contributor to neuropathology. J Child Neurol. 2009 Sep; 24(9):1147-57.
Score: 0.013
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Oxidative imbalance in nonstimulated X-adrenoleukodystrophy-derived lymphoblasts. Dev Neurosci. 2008; 30(6):410-8.
Score: 0.012
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Silencing of Abcd1 and Abcd2 genes sensitizes astrocytes for inflammation: implication for X-adrenoleukodystrophy. J Lipid Res. 2009 Jan; 50(1):135-47.
Score: 0.012
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Plasmalogen deficiency in cerebral adrenoleukodystrophy and its modulation by lovastatin. J Neurochem. 2008 Aug; 106(4):1766-79.
Score: 0.012
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Lactosylceramide: a lipid second messenger in neuroinflammatory disease. J Neurochem. 2007 Nov; 103 Suppl 1:180-91.
Score: 0.011
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Pharmacological strategies for the regulation of inducible nitric oxide synthase: neurodegenerative versus neuroprotective mechanisms. Neurochem Int. 2006 Jul; 49(2):170-82.
Score: 0.010
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Molecular organization of peroxisomal enzymes: protein-protein interactions in the membrane and in the matrix. Arch Biochem Biophys. 2006 Jul 15; 451(2):128-40.
Score: 0.010
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Sphingolipid signaling and redox regulation. Free Radic Biol Med. 2006 Jun 01; 40(11):1875-88.
Score: 0.010
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Rho/ROCK pathway as a target of tumor therapy. J Neurosci Res. 2006 Feb 01; 83(2):243-55.
Score: 0.010
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5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase. J Biol Chem. 2005 Nov 25; 280(47):39582-93.
Score: 0.010
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5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis. J Immunol. 2005 Jul 01; 175(1):566-74.
Score: 0.010
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Inhibition of peroxisomal functions due to oxidative imbalance induced by mistargeting of catalase to cytoplasm is restored by vitamin E treatment in skin fibroblasts from Zellweger syndrome-like patients. Mol Genet Metab. 2004 Dec; 83(4):297-305.
Score: 0.009
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Oral simvastatin treatment in relapsing-remitting multiple sclerosis. Lancet. 2004 May 15; 363(9421):1607-8.
Score: 0.009
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Correlation of very long chain fatty acid accumulation and inflammatory disease progression in childhood X-ALD: implications for potential therapies. Neurobiol Dis. 2003 Dec; 14(3):425-39.
Score: 0.009
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Rho A negatively regulates cytokine-mediated inducible nitric oxide synthase expression in brain-derived transformed cell lines: negative regulation of IKKalpha. Free Radic Biol Med. 2003 Nov 01; 35(9):1037-50.
Score: 0.008
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Peroxisomal fatty acid oxidation and cellular redox. Methods Enzymol. 2002; 352:361-72.
Score: 0.007
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Inducible nitric oxide synthase in the central nervous system of patients with X-adrenoleukodystrophy. J Neuropathol Exp Neurol. 2000 Dec; 59(12):1063-9.
Score: 0.007
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Identification of the pathway of alpha-oxidation of cerebronic acid in peroxisomes. Lipids. 2000 Oct; 35(10):1127-33.
Score: 0.007
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Characterization of fibroblast cytoplasmic proteins that bind to the 3' UTR of human catalase mRNA. Mol Cell Biochem. 2000 Jun; 209(1-2):9-15.
Score: 0.007
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Lovastatin therapy for X-linked adrenoleukodystrophy: clinical and biochemical observations on 12 patients. Mol Genet Metab. 2000 Apr; 69(4):312-22.
Score: 0.007
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Investigation of S-Nitrosoglutathione in stroke: A systematic review and meta-analysis of literature in pre-clinical and clinical research. Exp Neurol. 2020 06; 328:113262.
Score: 0.007
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Intraperoxisomal localization of very-long-chain fatty acyl-CoA synthetase: implication in X-adrenoleukodystrophy. Exp Cell Res. 2000 Feb 01; 254(2):309-20.
Score: 0.007
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Induction of the manganese superoxide dismutase gene by sphingomyelinase and ceramide. J Neurochem. 1999 Aug; 73(2):513-20.
Score: 0.006
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Regulation of endothelial barrier integrity by redox-dependent nitric oxide signaling: Implication in traumatic and inflammatory brain injuries. Nitric Oxide. 2019 02 01; 83:51-64.
Score: 0.006
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Localization of nervonic acid beta-oxidation in human and rodent peroxisomes: impaired oxidation in Zellweger syndrome and X-linked adrenoleukodystrophy. J Lipid Res. 1998 Nov; 39(11):2161-71.
Score: 0.006
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Restoration of phytanic acid oxidation in Refsum disease fibroblasts from patients with mutations in the phytanoyl-CoA hydroxylase gene. FEBS Lett. 1998 Jun 05; 429(1):119-22.
Score: 0.006
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Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy. FEBS Lett. 1998 Apr 24; 426(3):342-6.
Score: 0.006
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Abnormality in catalase import into peroxisomes leads to severe neurological disorder. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):2961-6.
Score: 0.006
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S-Nitrosylation in Regulation of Inflammation and Cell Damage. Curr Drug Targets. 2018; 19(15):1831-1838.
Score: 0.006
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Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. J Clin Invest. 1997 Dec 01; 100(11):2671-9.
Score: 0.006
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Biochemical features of a patient with Zellweger-like syndrome with normal PTS-1 and PTS-2 peroxisomal protein import systems: a new peroxisomal disease. Biochem Mol Med. 1997 Aug; 61(2):198-207.
Score: 0.006
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Emerging Markers of Early Brain Injury and Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage. World Neurosurg. 2017 Nov; 107:148-159.
Score: 0.006
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Regulation of STAT3 and NF-?B activations by S-nitrosylation in multiple myeloma. Free Radic Biol Med. 2017 05; 106:245-253.
Score: 0.005
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Biochemistry of peroxisomes in health and disease. Mol Cell Biochem. 1997 Feb; 167(1-2):1-29.
Score: 0.005
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Abnormality in translational regulation of catalase expression in disorders of peroxisomal biogenesis. J Neurochem. 1996 Dec; 67(6):2373-8.
Score: 0.005
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Topology of ATP-binding domain of adrenoleukodystrophy gene product in peroxisomes. Arch Biochem Biophys. 1996 Oct 15; 334(2):369-79.
Score: 0.005
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Cardiovascular Disease, Statins, and HIV. J Infect Dis. 2016 Oct 01; 214 Suppl 2:S83-92.
Score: 0.005
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Phytanic acid oxidation: normal activation and transport yet defective alpha-hydroxylation of phytanic acid in peroxisomes from Refsum disease and rhizomelic chondrodysplasia punctata. J Lipid Res. 1996 May; 37(5):1137-43.
Score: 0.005
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Epoxide hydrolase in human and rat peroxisomes: implication for disorders of peroxisomal biogenesis. J Lipid Res. 1996 Jan; 37(1):159-67.
Score: 0.005
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Ketoconazole and other imidazole derivatives are potent inhibitors of peroxisomal phytanic acid alpha-oxidation. FEBS Lett. 1995 Dec 18; 377(2):213-6.
Score: 0.005
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Molecular cloning and sequencing of human palmitoyl-CoA ligase and its tissue specific expression. Mol Cell Biochem. 1995 Oct 04; 151(1):77-81.
Score: 0.005
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The human palmitoyl-CoA ligase (FACL2) gene maps to the chromosome 4q34-q35 region by fluorescence in situ hybridization (FISH) and somatic cell hybrid panels. Genomics. 1995 Aug 10; 28(3):600-2.
Score: 0.005
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Phytanic acid oxidation: topographical localization of phytanoyl-CoA ligase and transport of phytanic acid into human peroxisomes. J Lipid Res. 1995 May; 36(5):986-97.
Score: 0.005
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Effect of hypoxia-reoxygenation on peroxisomal functions in cultured human skin fibroblasts from control and Zellweger syndrome patients. Free Radic Res. 1995 Jan; 22(1):39-46.
Score: 0.005
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Effect of vitamin D3 intake on the onset of disease in a murine model of human Krabbe disease. J Neurosci Res. 2015 Jan; 93(1):28-42.
Score: 0.005
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The protein coded by the X-adrenoleukodystrophy gene is a peroxisomal integral membrane protein. FEBS Lett. 1994 May 16; 344(2-3):211-5.
Score: 0.004
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Intraorganellar localization of CoASH-independent phytanic acid oxidation in human liver peroxisomes. FEBS Lett. 1993 Oct 25; 333(1-2):154-8.
Score: 0.004
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Refsum disease: a defect in the alpha-oxidation of phytanic acid in peroxisomes. J Lipid Res. 1993 Oct; 34(10):1755-64.
Score: 0.004
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Phytanic acid alpha-oxidation. Differential subcellular localization in rat and human tissues and its inhibition by nycodenz. J Biol Chem. 1993 May 15; 268(14):9972-9.
Score: 0.004
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Identification of phytanoyl-CoA ligase as a distinct acyl-CoA ligase in peroxisomes from cultured human skin fibroblasts. FEBS Lett. 1993 May 10; 322(2):101-4.
Score: 0.004
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Role of endogenous psychosine accumulation in oligodendrocyte differentiation and survival: implication for Krabbe disease. Brain Res. 2013 May 01; 1508:44-52.
Score: 0.004
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Phytanic acid alpha-oxidation in human cultured skin fibroblasts. Biochim Biophys Acta. 1992 Dec 10; 1180(2):221-4.
Score: 0.004
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Transport of fatty acids into human and rat peroxisomes. Differential transport of palmitic and lignoceric acids and its implication to X-adrenoleukodystrophy. J Biol Chem. 1992 Jul 05; 267(19):13306-13.
Score: 0.004
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Berry anthocyanidins synergistically suppress growth and invasive potential of human non-small-cell lung cancer cells. Cancer Lett. 2012 Dec 01; 325(1):54-62.
Score: 0.004
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Complementation in Zellweger syndrome: biochemical analysis of newly generated peroxisomes. Hum Hered. 1992; 42(3):172-8.
Score: 0.004
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Chromosomal localization of the human gene for palmitoyl-CoA ligase (FACL1). Cytogenet Cell Genet. 1992; 59(1):17-9.
Score: 0.004
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Progressive endoplasmic reticulum stress contributes to hepatocarcinogenesis in fatty acyl-CoA oxidase 1-deficient mice. Am J Pathol. 2011 Aug; 179(2):703-13.
Score: 0.004
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Rhizomelic chondrodysplasia punctata: biochemical studies of peroxisomes isolated from cultured skin fibroblasts. Arch Biochem Biophys. 1991 Apr; 286(1):277-83.
Score: 0.004
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Increased Plp1 gene expression leads to massive microglial cell activation and inflammation throughout the brain. ASN Neuro. 2010 Sep 27; 2(4):e00043.
Score: 0.003
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Cellular oxidation of lignoceric acid is regulated by the subcellular localization of lignoceroyl-CoA ligases. J Lipid Res. 1990 Apr; 31(4):583-95.
Score: 0.003
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Reversal of mouse Acyl-CoA oxidase 1 (ACOX1) null phenotype by human ACOX1b isoform [corrected]. Lab Invest. 2010 May; 90(5):696-708.
Score: 0.003
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Adrenal autoantibodies bind to adrenal subcellular fractions enriched in cytochrome-c reductase and 5'-nucleotidase. J Clin Endocrinol Metab. 1990 Jan; 70(1):95-9.
Score: 0.003
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Adrenoleukodystrophy: impaired oxidation of fatty acids due to peroxisomal lignoceroyl-CoA ligase deficiency. Arch Biochem Biophys. 1989 May 01; 270(2):722-8.
Score: 0.003
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Peroxisomal disorders. Biochemical and clinical diagnostic considerations. Am J Dis Child. 1988 Dec; 142(12):1297-301.
Score: 0.003
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Peroxisomal lignoceroyl-CoA ligase deficiency in childhood adrenoleukodystrophy and adrenomyeloneuropathy. Proc Natl Acad Sci U S A. 1988 Oct; 85(20):7647-51.
Score: 0.003
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Psychosine-induced alterations in peroxisomes of twitcher mouse liver. Arch Biochem Biophys. 2008 Sep 15; 477(2):211-8.
Score: 0.003
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Lipopolysaccharide-induced peroxisomal dysfunction exacerbates cerebral white matter injury: attenuation by N-acetyl cysteine. Exp Neurol. 2008 Apr; 210(2):560-76.
Score: 0.003
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Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy. Mol Cancer. 2007 Jul 10; 6:46.
Score: 0.003
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Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis. Am J Pathol. 2006 Sep; 169(3):1012-25.
Score: 0.003
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Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma. Am J Pathol. 2006 Sep; 169(3):1039-47.
Score: 0.003
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Immunomodulatory effects of 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitors, potential therapy for relapsing remitting multiple sclerosis. J Neuroimmunol. 2006 Sep; 178(1-2):130-9.
Score: 0.003
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Krabbe disease: psychosine-mediated activation of phospholipase A2 in oligodendrocyte cell death. J Lipid Res. 2006 Jul; 47(7):1478-92.
Score: 0.003
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N-acetylcysteine prevents endotoxin-induced degeneration of oligodendrocyte progenitors and hypomyelination in developing rat brain. J Neurosci Res. 2004 Nov 01; 78(3):347-61.
Score: 0.002
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Molecular mechanism of psychosine-induced cell death in human oligodendrocyte cell line. J Neurochem. 2003 Sep; 86(6):1428-40.
Score: 0.002
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Effect of rhinovirus challenge on antioxidant enzymes in respiratory epithelial cells. Free Radic Res. 2002 Oct; 36(10):1085-9.
Score: 0.002
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Rhinovirus-induced oxidative stress and interleukin-8 elaboration involves p47-phox but is independent of attachment to intercellular adhesion molecule-1 and viral replication. J Infect Dis. 2000 Jun; 181(6):1885-90.
Score: 0.002
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Effect of nitric oxide on rhinovirus replication and virus-induced interleukin-8 elaboration. Am J Respir Crit Care Med. 1999 Apr; 159(4 Pt 1):1193-8.
Score: 0.002
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The role of oxidative stress in rhinovirus induced elaboration of IL-8 by respiratory epithelial cells. Free Radic Biol Med. 1999 Feb; 26(3-4):454-62.
Score: 0.002
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In situ genetic complementation analysis of cells with generalized peroxisomal dysfunction. Hum Hered. 1989; 39(5):298-301.
Score: 0.001
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Reye syndrome: rate of oxidation of fatty acids in leukocytes and serum levels of lipid peroxides. J Exp Pathol. 1989; 4(3):133-9.
Score: 0.001