Connection

Charles Smith to Animals

This is a "connection" page, showing publications Charles Smith has written about Animals.
Connection Strength

0.486
  1. Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression. Mol Cancer Res. 2015 Dec; 13(12):1591-601.
    View in: PubMed
    Score: 0.038
  2. Discovery and evaluation of inhibitors of human ceramidase. Mol Cancer Ther. 2011 Nov; 10(11):2052-61.
    View in: PubMed
    Score: 0.029
  3. Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts. Cancer Biol Ther. 2011 Mar 01; 11(5):524-34.
    View in: PubMed
    Score: 0.028
  4. Combined anticancer effects of sphingosine kinase inhibitors and sorafenib. Invest New Drugs. 2011 Dec; 29(6):1132-42.
    View in: PubMed
    Score: 0.026
  5. DHHC20: a human palmitoyl acyltransferase that causes cellular transformation. Mol Membr Biol. 2010 Apr; 27(2-3):123-36.
    View in: PubMed
    Score: 0.026
  6. A novel sphingosine kinase inhibitor induces autophagy in tumor cells. J Pharmacol Exp Ther. 2010 May; 333(2):454-64.
    View in: PubMed
    Score: 0.026
  7. Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2. J Pharmacol Exp Ther. 2010 Apr; 333(1):129-39.
    View in: PubMed
    Score: 0.026
  8. Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. J Med Chem. 2009 Jan 08; 52(1):74-86.
    View in: PubMed
    Score: 0.024
  9. Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase. Dig Dis Sci. 2008 Apr; 53(4):997-1012.
    View in: PubMed
    Score: 0.022
  10. Discovery of novel antitumor antimitotic agents that also reverse tumor resistance. J Med Chem. 2007 Jul 12; 50(14):3290-301.
    View in: PubMed
    Score: 0.022
  11. Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. Mol Cancer Res. 2005 Aug; 3(8):463-76.
    View in: PubMed
    Score: 0.019
  12. Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein. J Med Chem. 2004 Mar 11; 47(6):1413-22.
    View in: PubMed
    Score: 0.017
  13. Discovery and evaluation of inhibitors of human sphingosine kinase. Cancer Res. 2003 Sep 15; 63(18):5962-9.
    View in: PubMed
    Score: 0.017
  14. Characterization of human palmitoyl-acyl transferase activity using peptides that mimic distinct palmitoylation motifs. Biochem J. 2003 Jul 01; 373(Pt 1):91-9.
    View in: PubMed
    Score: 0.016
  15. ABC294640, A Novel Sphingosine Kinase 2 Inhibitor, Induces Oncogenic Virus-Infected Cell Autophagic Death and Represses Tumor Growth. Mol Cancer Ther. 2017 Dec; 16(12):2724-2734.
    View in: PubMed
    Score: 0.011
  16. Tissue biomarkers of drug efficacy: case studies using a MALDI-MSI workflow. Bioanalysis. 2015; 7(20):2611-9.
    View in: PubMed
    Score: 0.010
  17. The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo. Mol Cancer Ther. 2015 Dec; 14(12):2744-52.
    View in: PubMed
    Score: 0.010
  18. Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. Sci Signal. 2015 Jun 16; 8(381):ra58.
    View in: PubMed
    Score: 0.009
  19. Minocycline and doxycycline, but not other tetracycline-derived compounds, protect liver cells from chemical hypoxia and ischemia/reperfusion injury by inhibition of the mitochondrial calcium uniporter. Toxicol Appl Pharmacol. 2013 Nov 15; 273(1):172-9.
    View in: PubMed
    Score: 0.008
  20. Impact of sphingosine kinase 2 deficiency on the development of TNF-alpha-induced inflammatory arthritis. Rheumatol Int. 2013 Oct; 33(10):2677-81.
    View in: PubMed
    Score: 0.008
  21. Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats. PLoS One. 2012; 7(7):e41834.
    View in: PubMed
    Score: 0.008
  22. Rapid histamine-induced neutrophil recruitment is sphingosine kinase-1 dependent. Am J Pathol. 2012 Apr; 180(4):1740-50.
    View in: PubMed
    Score: 0.007
  23. Quinacrine sensitizes hepatocellular carcinoma cells to TRAIL and chemotherapeutic agents. Cancer Biol Ther. 2011 Aug 01; 12(3):229-38.
    View in: PubMed
    Score: 0.007
  24. Quinacrine synergizes with 5-fluorouracil and other therapies in colorectal cancer. Cancer Biol Ther. 2011 Aug 01; 12(3):239-51.
    View in: PubMed
    Score: 0.007
  25. Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion. J Hepatol. 2012 Jan; 56(1):137-45.
    View in: PubMed
    Score: 0.007
  26. Targeting NF?B mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2. Cancer Biol Ther. 2011 Apr 01; 11(7):678-89.
    View in: PubMed
    Score: 0.007
  27. The Pim protein kinases regulate energy metabolism and cell growth. Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2):528-33.
    View in: PubMed
    Score: 0.007
  28. Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase. Carcinogenesis. 2010 Oct; 31(10):1787-93.
    View in: PubMed
    Score: 0.007
  29. Sorafenib inhibits ERK1/2 and MCL-1(L) phosphorylation levels resulting in caspase-independent cell death in malignant pleural mesothelioma. Cancer Biol Ther. 2009 Dec; 8(24):2406-16.
    View in: PubMed
    Score: 0.006
  30. A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma. Blood. 2010 Jan 28; 115(4):824-33.
    View in: PubMed
    Score: 0.006
  31. PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells. Cancer Biol Ther. 2009 May; 8(9):846-53.
    View in: PubMed
    Score: 0.006
  32. Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death. Cancer Cell. 2007 Jul; 12(1):66-80.
    View in: PubMed
    Score: 0.005
  33. Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors. Cancer Res. 2005 Mar 15; 65(6):2412-21.
    View in: PubMed
    Score: 0.005
  34. Credentialing of research surgeons: can computers help in the process? J Invest Surg. 1996 May-Jun; 9(3):159-60.
    View in: PubMed
    Score: 0.003
  35. Paired box gene expression in Wilms' tumor. J Pediatr Surg. 1994 Feb; 29(2):134-41.
    View in: PubMed
    Score: 0.002
  36. Hanford miniature swine model for extracorporeal membrane oxygenation. J Invest Surg. 1993 Nov-Dec; 6(6):503-8.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.