Charles Smith to Mice
This is a "connection" page, showing publications Charles Smith has written about Mice.
Connection Strength
0.621
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Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression. Mol Cancer Res. 2015 Dec; 13(12):1591-601.
Score: 0.055
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Discovery and evaluation of inhibitors of human ceramidase. Mol Cancer Ther. 2011 Nov; 10(11):2052-61.
Score: 0.042
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Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts. Cancer Biol Ther. 2011 Mar 01; 11(5):524-34.
Score: 0.041
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Combined anticancer effects of sphingosine kinase inhibitors and sorafenib. Invest New Drugs. 2011 Dec; 29(6):1132-42.
Score: 0.038
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DHHC20: a human palmitoyl acyltransferase that causes cellular transformation. Mol Membr Biol. 2010 Apr; 27(2-3):123-36.
Score: 0.038
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A novel sphingosine kinase inhibitor induces autophagy in tumor cells. J Pharmacol Exp Ther. 2010 May; 333(2):454-64.
Score: 0.038
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Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2. J Pharmacol Exp Ther. 2010 Apr; 333(1):129-39.
Score: 0.038
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Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. J Med Chem. 2009 Jan 08; 52(1):74-86.
Score: 0.035
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Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase. Dig Dis Sci. 2008 Apr; 53(4):997-1012.
Score: 0.032
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Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis. Mol Cancer Res. 2005 Aug; 3(8):463-76.
Score: 0.028
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Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein. J Med Chem. 2004 Mar 11; 47(6):1413-22.
Score: 0.025
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Discovery and evaluation of inhibitors of human sphingosine kinase. Cancer Res. 2003 Sep 15; 63(18):5962-9.
Score: 0.024
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ABC294640, A Novel Sphingosine Kinase 2 Inhibitor, Induces Oncogenic Virus-Infected Cell Autophagic Death and Represses Tumor Growth. Mol Cancer Ther. 2017 Dec; 16(12):2724-2734.
Score: 0.016
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Tissue biomarkers of drug efficacy: case studies using a MALDI-MSI workflow. Bioanalysis. 2015; 7(20):2611-9.
Score: 0.014
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The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo. Mol Cancer Ther. 2015 Dec; 14(12):2744-52.
Score: 0.014
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Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. Sci Signal. 2015 Jun 16; 8(381):ra58.
Score: 0.014
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Impact of sphingosine kinase 2 deficiency on the development of TNF-alpha-induced inflammatory arthritis. Rheumatol Int. 2013 Oct; 33(10):2677-81.
Score: 0.011
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Rapid histamine-induced neutrophil recruitment is sphingosine kinase-1 dependent. Am J Pathol. 2012 Apr; 180(4):1740-50.
Score: 0.011
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Quinacrine sensitizes hepatocellular carcinoma cells to TRAIL and chemotherapeutic agents. Cancer Biol Ther. 2011 Aug 01; 12(3):229-38.
Score: 0.010
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Quinacrine synergizes with 5-fluorouracil and other therapies in colorectal cancer. Cancer Biol Ther. 2011 Aug 01; 12(3):239-51.
Score: 0.010
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Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion. J Hepatol. 2012 Jan; 56(1):137-45.
Score: 0.010
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Targeting NF?B mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2. Cancer Biol Ther. 2011 Apr 01; 11(7):678-89.
Score: 0.010
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The Pim protein kinases regulate energy metabolism and cell growth. Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2):528-33.
Score: 0.010
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Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase. Carcinogenesis. 2010 Oct; 31(10):1787-93.
Score: 0.010
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Sorafenib inhibits ERK1/2 and MCL-1(L) phosphorylation levels resulting in caspase-independent cell death in malignant pleural mesothelioma. Cancer Biol Ther. 2009 Dec; 8(24):2406-16.
Score: 0.009
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A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma. Blood. 2010 Jan 28; 115(4):824-33.
Score: 0.009
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PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells. Cancer Biol Ther. 2009 May; 8(9):846-53.
Score: 0.009
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Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death. Cancer Cell. 2007 Jul; 12(1):66-80.
Score: 0.008
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Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors. Cancer Res. 2005 Mar 15; 65(6):2412-21.
Score: 0.007
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Paired box gene expression in Wilms' tumor. J Pediatr Surg. 1994 Feb; 29(2):134-41.
Score: 0.003