Kenneth Tew to Animals
This is a "connection" page, showing publications Kenneth Tew has written about Animals.
Connection Strength
1.607
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Glutathione S-Transferase P Influences Redox Homeostasis and Response to Drugs that Induce the Unfolded Protein Response in Zebrafish. J Pharmacol Exp Ther. 2021 04; 377(1):121-132.
Score: 0.054
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Oxidative Stress in Cancer. Cancer Cell. 2020 08 10; 38(2):167-197.
Score: 0.052
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An evolving understanding of the S-glutathionylation cycle in pathways of redox regulation. Free Radic Biol Med. 2018 05 20; 120:204-216.
Score: 0.044
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ATP-binding cassette transporter-2 (ABCA2) as a therapeutic target. Biochem Pharmacol. 2018 05; 151:188-200.
Score: 0.043
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Commentary on "Proteasome Inhibitors: A Novel Class of Potent and Effective Antitumor Agents". Cancer Res. 2016 09 01; 76(17):4916-7.
Score: 0.040
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Glutathione S-Transferase P-Mediated Protein S-Glutathionylation of Resident Endoplasmic Reticulum Proteins Influences Sensitivity to Drug-Induced Unfolded Protein Response. Antioxid Redox Signal. 2017 02 20; 26(6):247-261.
Score: 0.038
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Glutathione-Associated Enzymes In Anticancer Drug Resistance. Cancer Res. 2016 Jan 01; 76(1):7-9.
Score: 0.038
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Glutathione S-transferase P influences redox and migration pathways in bone marrow. PLoS One. 2014; 9(9):e107478.
Score: 0.035
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Causes and consequences of cysteine S-glutathionylation. J Biol Chem. 2013 Sep 13; 288(37):26497-504.
Score: 0.032
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Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies. Biomed Pharmacother. 2012 Sep; 66(6):403-8.
Score: 0.030
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Glutathione-s-transferases as determinants of cell survival and death. Antioxid Redox Signal. 2012 Dec 15; 17(12):1728-37.
Score: 0.030
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S-glutathionylated serine proteinase inhibitors as plasma biomarkers in assessing response to redox-modulating drugs. Cancer Res. 2012 May 01; 72(9):2383-93.
Score: 0.029
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NrF2 /Keap1 as gatekeepers of redox homeostasis ? do they prevent or cause cancer? Pigment Cell Melanoma Res. 2011 Dec; 24(6):1078-9.
Score: 0.029
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Redox platforms in cancer drug discovery and development. Curr Opin Chem Biol. 2011 Feb; 15(1):156-61.
Score: 0.027
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ABCA2 transporter deficiency reduces incidence of TRAMP prostate tumor metastasis and cellular chemotactic migration. Cancer Lett. 2011 Jan 28; 300(2):154-61.
Score: 0.026
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The impact of redox and thiol status on the bone marrow: Pharmacological intervention strategies. Pharmacol Ther. 2011 Feb; 129(2):172-84.
Score: 0.026
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Novel role for glutathione S-transferase pi. Regulator of protein S-Glutathionylation following oxidative and nitrosative stress. J Biol Chem. 2009 Jan 02; 284(1):436-445.
Score: 0.023
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Pharmacology of a mimetic of glutathione disulfide, NOV-002. Biomed Pharmacother. 2009 Feb; 63(2):75-8.
Score: 0.023
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NOV-002, a mimetic of glutathione disulfide. Expert Opin Investig Drugs. 2008 Jul; 17(7):1075-83.
Score: 0.023
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ABCA2 as a therapeutic target in cancer and nervous system disorders. Expert Opin Ther Targets. 2008 Apr; 12(4):491-504.
Score: 0.022
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"Skittish" Abca2 knockout mice display tremor, hyperactivity, and abnormal myelin ultrastructure in the central nervous system. Mol Cell Biol. 2007 Jan; 27(1):44-53.
Score: 0.020
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Redox in redux: Emergent roles for glutathione S-transferase P (GSTP) in regulation of cell signaling and S-glutathionylation. Biochem Pharmacol. 2007 May 01; 73(9):1257-69.
Score: 0.020
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A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins. Mol Pharmacol. 2006 Feb; 69(2):501-8.
Score: 0.019
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TLK-286: a novel glutathione S-transferase-activated prodrug. Expert Opin Investig Drugs. 2005 Aug; 14(8):1047-54.
Score: 0.018
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Characterization of the ATPase activity of human ATP-binding cassette transporter-2 (ABCA2). In Vivo. 2005 Jul-Aug; 19(4):657-60.
Score: 0.018
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Influence of glutathione S-transferase pi and p53 expression on tumor frequency and spectrum in mice. Int J Cancer. 2005 Jan 01; 113(1):29-35.
Score: 0.018
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Glutathione S-transferases as regulators of kinase pathways and anticancer drug targets. Methods Enzymol. 2005; 401:287-307.
Score: 0.018
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Glutathione and ABC transporters as determinants of sensitivity to oxidative and nitrosative stress. J Nutr. 2004 Nov; 134(11):3205S-3206S.
Score: 0.017
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Human ATP-binding cassette transporter-2 (ABCA2) positively regulates low-density lipoprotein receptor expression and negatively regulates cholesterol esterification in Chinese hamster ovary cells. Biochim Biophys Acta. 2004 Jul 05; 1683(1-3):89-100.
Score: 0.017
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Tumor cell responses to a novel glutathione S-transferase-activated nitric oxide-releasing prodrug. Mol Pharmacol. 2004 May; 65(5):1070-9.
Score: 0.017
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Identification of a novel first exon of the human ABCA2 transporter gene encoding a unique N-terminus. Biochim Biophys Acta. 2004 Apr 16; 1678(1):22-32.
Score: 0.017
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Organosulfur compounds from alliaceae in the prevention of human pathologies. Biomed Pharmacother. 2004 Apr; 58(3):183-93.
Score: 0.017
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Small molecule inhibition of hypoxia inducible factor-1alpha: a viable therapeutic approach? Mol Cancer Ther. 2004 Mar; 3(3):245-6.
Score: 0.017
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Increased myeloproliferation in glutathione S-transferase pi-deficient mice is associated with a deregulation of JNK and Janus kinase/STAT pathways. J Biol Chem. 2004 Mar 05; 279(10):8608-16.
Score: 0.016
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Trace elements in human physiology and pathology. Copper. Biomed Pharmacother. 2003 Nov; 57(9):386-98.
Score: 0.016
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Trace elements in human physiology and pathology: zinc and metallothioneins. Biomed Pharmacother. 2003 Nov; 57(9):399-411.
Score: 0.016
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The antioxidant role of selenium and seleno-compounds. Biomed Pharmacother. 2003 May-Jun; 57(3-4):134-44.
Score: 0.016
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Reciprocal regulation of expression of the human adenosine 5'-triphosphate binding cassette, sub-family A, transporter 2 (ABCA2) promoter by the early growth response-1 (EGR-1) and Sp-family transcription factors. Nucleic Acids Res. 2003 Feb 01; 31(3):1097-107.
Score: 0.015
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I. Arginine. Biomed Pharmacother. 2002 Nov; 56(9):439-45.
Score: 0.015
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II. Glutamine and glutamate. Biomed Pharmacother. 2002 Nov; 56(9):446-57.
Score: 0.015
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Estrogens and environmental estrogens. Biomed Pharmacother. 2002 Feb; 56(1):36-44.
Score: 0.014
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Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia. J Clin Invest. 2021 08 16; 131(16).
Score: 0.014
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Binding of the aminothiol WR-1065 to transcription factors influences cellular response to anticancer drugs. J Pharmacol Exp Ther. 2001 Jun; 297(3):1067-73.
Score: 0.014
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Cloning and characterization of human adenosine 5'-triphosphate-binding cassette, sub-family A, transporter 2 (ABCA2). Cancer Res. 2001 Apr 15; 61(8):3339-47.
Score: 0.014
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Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus. J Biol Chem. 2001 Jun 15; 276(24):20999-1003.
Score: 0.014
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Cellular thiols and reactive oxygen species in drug-induced apoptosis. J Pharmacol Exp Ther. 2001 Jan; 296(1):1-6.
Score: 0.013
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The influence of coordinate overexpression of glutathione phase II detoxification gene products on drug resistance. J Pharmacol Exp Ther. 2000 Aug; 294(2):480-7.
Score: 0.013
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Cellular response to a glutathione S-transferase P1-1 activated prodrug. Mol Pharmacol. 2000 Jul; 58(1):167-74.
Score: 0.013
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Glutathione peptidomimetic drug modulator of multidrug resistance-associated protein. J Pharmacol Exp Ther. 1999 Dec; 291(3):1348-55.
Score: 0.012
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A seleno-hormetine protects bone marrow hematopoietic cells against ionizing radiation-induced toxicities. PLoS One. 2019; 14(4):e0205626.
Score: 0.012
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Increased expression of DNA-dependent protein kinase confers resistance to adriamycin. Biochim Biophys Acta. 1998 Jul 23; 1381(2):131-8.
Score: 0.011
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Impact of dietary supplement of Crassostrea gigas extract (JCOE) on glutathione levels and glutathione S-transferase activity in rat tissues. In Vivo. 1998 May-Jun; 12(3):299-303.
Score: 0.011
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The antioxidant effects of Crassostrea gigas extract (JCOE) in human volunteers. In Vivo. 1998 May-Jun; 12(3):305-9.
Score: 0.011
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Coordinate changes in expression of protective genes in drug-resistant cells. Chem Biol Interact. 1998 Apr 24; 111-112:199-211.
Score: 0.011
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MGST1, a GSH transferase/peroxidase essential for development and hematopoietic stem cell differentiation. Redox Biol. 2018 07; 17:171-179.
Score: 0.011
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S-Glutathionylation of estrogen receptor a affects dendritic cell function. J Biol Chem. 2018 03 23; 293(12):4366-4380.
Score: 0.011
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Selenocompounds in Cancer Therapy: An Overview. Adv Cancer Res. 2017; 136:259-302.
Score: 0.011
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MYC Inhibition Depletes Cancer Stem-like Cells in Triple-Negative Breast Cancer. Cancer Res. 2017 12 01; 77(23):6641-6650.
Score: 0.011
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Interaction of estramustine with tubulin isotypes. Biochemistry. 1997 Jan 28; 36(4):871-8.
Score: 0.010
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Adaptive response to glutathione S-transferase inhibitors. Br J Cancer Suppl. 1996 Jul; 27:S93-8.
Score: 0.010
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Glutathione S-transferase pi modulates NF-?B activation and pro-inflammatory responses in lung epithelial cells. Redox Biol. 2016 08; 8:375-82.
Score: 0.010
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Adverse Outcomes Associated with Cigarette Smoke Radicals Related to Damage to Protein-disulfide Isomerase. J Biol Chem. 2016 Feb 26; 291(9):4763-78.
Score: 0.009
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Increased glutathione expression in cells induced by Crassostera gigas extract (JCOE). Biomed Pharmacother. 1996; 50(3-4):149-53.
Score: 0.009
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Glutathione S-transferases. Cancer Treat Res. 1996; 87:83-122.
Score: 0.009
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Glyoxalase I in detoxification: studies using a glyoxalase I transfectant cell line. Biochem J. 1995 Jul 01; 309 ( Pt 1):127-31.
Score: 0.009
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Interaction of an estramustine photoaffinity analogue with cytoskeletal proteins in prostate carcinoma cells. Mol Pharmacol. 1994 Nov; 46(5):866-72.
Score: 0.009
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Reaction kinetics and targeting to cellular glutathione S-transferase of the glutathione peroxidase mimetic PhSeZnCl and its D,L-polylactide microparticle formulation. Free Radic Biol Med. 2015 Jan; 78:56-65.
Score: 0.009
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cDNA and deduced amino acid sequences of a human colon dihydrodiol dehydrogenase. Biochim Biophys Acta. 1994 Jun 28; 1186(1-2):129-32.
Score: 0.009
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Pleiotropic functions of glutathione S-transferase P. Adv Cancer Res. 2014; 122:143-75.
Score: 0.008
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Analysis of glyoxalase-I from normal and tumor tissue from human colon. Biochim Biophys Acta. 1993 Oct 20; 1182(3):311-6.
Score: 0.008
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Time course of glutathione S-transferase elevation in Walker mammary carcinoma cells following chlorambucil exposure. Biochem Pharmacol. 1993 Feb 09; 45(3):683-90.
Score: 0.008
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Preclinical and clinical perspectives on the use of estramustine as an antimitotic drug. Pharmacol Ther. 1992 Dec; 56(3):323-39.
Score: 0.008
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Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis. Mol Cell Biol. 2012 Sep; 32(17):3464-78.
Score: 0.007
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Macrophage ABCA2 deletion modulates intracellular cholesterol deposition, affects macrophage apoptosis, and decreases early atherosclerosis in LDL receptor knockout mice. Atherosclerosis. 2012 Aug; 223(2):332-41.
Score: 0.007
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Developmental expression of orphan G protein-coupled receptor 50 in the mouse brain. ACS Chem Neurosci. 2012 Jun 20; 3(6):459-72.
Score: 0.007
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Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-? production by altering Nicastrin maturation and intracellular localization. J Biol Chem. 2012 Jan 06; 287(2):1100-11.
Score: 0.007
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Cocaine-induced adaptations in cellular redox balance contributes to enduring behavioral plasticity. Neuropsychopharmacology. 2011 Nov; 36(12):2551-60.
Score: 0.007
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Evidence for a glycoconjugate form of glutathione S-transferase pI. Int J Pept Protein Res. 1991 Jun; 37(6):565-71.
Score: 0.007
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S-glutathionylation: from molecular mechanisms to health outcomes. Antioxid Redox Signal. 2011 Jul 01; 15(1):233-70.
Score: 0.007
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Detoxification mechanisms and tumor cell resistance to anticancer drugs. Med Res Rev. 1991 Mar; 11(2):185-217.
Score: 0.007
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Mechanism based chemotherapy for prostate cancer. Cancer Surv. 1991; 11:239-54.
Score: 0.007
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Glutathione-S-transferase pi as a determinant of drug resistance in transfectant cell lines. J Biol Chem. 1990 Mar 15; 265(8):4296-301.
Score: 0.006
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Preclinical pharmacokinetic analysis of NOV-002, a glutathione disulfide mimetic. Biomed Pharmacother. 2010 Sep; 64(7):493-8.
Score: 0.006
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Protective effects of a glutathione disulfide mimetic (NOV-002) against cisplatin induced kidney toxicity. Biomed Pharmacother. 2010 Jan; 64(1):73-6.
Score: 0.006
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Identification of a glutathione S-transferase associated with microsomes of tumor cells resistant to nitrogen mustards. Biochem Pharmacol. 1989 Jun 15; 38(12):1915-21.
Score: 0.006
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Glutathione, glutathione S-transferases, and related redox enzymes in Adriamycin-resistant cell lines with a multidrug resistant phenotype. Cancer Commun. 1989; 1(2):133-9.
Score: 0.006
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Estramustine--a nitrogen mustard/steroid with antimicrotubule activity. Pharmacol Ther. 1989; 43(3):299-319.
Score: 0.006
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Purification of glutathione S-transferases from rat liver and Walker 256 mammary carcinoma cells by high-performance liquid chromatography and a glutathione affinity column. J Chromatogr. 1988 Dec 29; 434(1):83-93.
Score: 0.006
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Role of glutathione S-transferase Pi in cisplatin-induced nephrotoxicity. Biomed Pharmacother. 2009 Feb; 63(2):79-85.
Score: 0.006
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Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines. Cancer Res. 1988 Jul 01; 48(13):3622-5.
Score: 0.006
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Estramustine binds MAP-2 to inhibit microtubule assembly in vitro. J Cell Sci. 1988 Mar; 89 ( Pt 3):331-42.
Score: 0.006
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Glutathione S-transferases in nitrogen mustard-resistant and -sensitive cell lines. Mol Pharmacol. 1987 Jun; 31(6):575-8.
Score: 0.005
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Hormone-independent, non-alkylating mechanism of cytotoxicity for estramustine. Urol Res. 1987; 15(3):155-60.
Score: 0.005
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Differences in the nuclear matrix phosphoproteins of a wild-type and nitrogen mustard-resistant rat breast carcinoma cell line. Cancer Res. 1986 Sep; 46(9):4672-6.
Score: 0.005
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The ATP-binding cassette transporter ABCA2 as a mediator of intracellular trafficking. Biomed Pharmacother. 2006 Nov; 60(9):587-92.
Score: 0.005
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Selection of nitrogen mustard resistance in a rat tumor cell line results in loss of guanine-O6-alkyl transferase activity. Mol Pharmacol. 1986 Jul; 30(1):77-80.
Score: 0.005
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A comparative analysis of drug-induced DNA effects in a nitrogen mustard resistant cell line expressing sensitivity to nitrosoureas. Biochem Pharmacol. 1986 Apr 01; 35(7):1171-6.
Score: 0.005
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PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity. J Med Chem. 2006 Feb 09; 49(3):1157-64.
Score: 0.005
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Dansylated estramustine, a fluorescent probe for studies of estramustine uptake and identification of intracellular targets. Proc Natl Acad Sci U S A. 1985 Dec; 82(24):8483-7.
Score: 0.005
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Antimicrotubule effects of estramustine, an antiprostatic tumor drug. Cancer Res. 1985 Aug; 45(8):3891-7.
Score: 0.005
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Poly(adenosine diphosphate-ribosylation) of nuclear matrix proteins in alkylating agent resistant and sensitive cell lines. Chem Biol Interact. 1985 Jul; 54(2):209-22.
Score: 0.005
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Increased glutathione-S-transferase activity in a cell line with acquired resistance to nitrogen mustards. Cancer Treat Rep. 1985 Jun; 69(6):677-82.
Score: 0.005
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Carbamoylation of glutathione reductase and changes in cellular and chromosome morphology in a rat cell line resistant to nitrogen mustards but collaterally sensitive to nitrosoureas. Cancer Res. 1985 May; 45(5):2326-33.
Score: 0.005
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Biochemical and cytotoxic properties of the isomeric forms of N,N'-bis[N-2-chloroethyl)-N-nitrosocarbamoyl] cystamine. Biochem Pharmacol. 1984 Aug 15; 33(16):2575-80.
Score: 0.004
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Cytotoxic properties of estramustine unrelated to alkylating and steroid constituents. Urology. 1984 Jun; 23(6 Suppl):28-33.
Score: 0.004
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Sulfur containing amino acids and human disease. Biomed Pharmacother. 2004 Jan; 58(1):47-55.
Score: 0.004
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The mechanism of action of estramustine. Semin Oncol. 1983 Sep; 10(3 Suppl 3):21-6.
Score: 0.004
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Cytotoxicity of estramustine, a steroid-nitrogen mustard derivative, through non-DNA targets. Mol Pharmacol. 1983 Sep; 24(2):324-8.
Score: 0.004
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Molecular modes of action of artesunate in tumor cell lines. Mol Pharmacol. 2003 Aug; 64(2):382-94.
Score: 0.004
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Selective cytotoxicity of haloethylnitrosoureas in a carcinoma cell line resistant to bifunctional nitrogen mustards. Mol Pharmacol. 1982 May; 21(3):729-38.
Score: 0.004
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Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases. Cancer Res. 2000 Aug 01; 60(15):4053-7.
Score: 0.003
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Cyclophosphamide and cis-dichlorodiammine platinum (11). Nonempiric scheduling to spare dose-limiting tissues in the rat. Cancer Chemother Pharmacol. 1980; 4(2):103-9.
Score: 0.003
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Double high-dose chemotherapy with stem cell rescue (HD-SCR) in patients with breast cancer - effect of sequence. Cancer Chemother Pharmacol. 2000; 45(3):239-46.
Score: 0.003
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Role of redox potential and reactive oxygen species in stress signaling. Oncogene. 1999 Nov 01; 18(45):6104-11.
Score: 0.003
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Oxidative stress induced in pathologies: the role of antioxidants. Biomed Pharmacother. 1999 May; 53(4):169-80.
Score: 0.003
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Regulation of JNK signaling by GSTp. EMBO J. 1999 Mar 01; 18(5):1321-34.
Score: 0.003
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Tumor efficacy and bone marrow-sparing properties of TER286, a cytotoxin activated by glutathione S-transferase. Cancer Res. 1998 Jun 15; 58(12):2568-75.
Score: 0.003
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The relationship of thymidine metabolism to the use of fractional incorporation as a measure of DNA synthesis and tissue proliferation. Eur J Cancer (1965). 1978 Feb; 14(2):153-68.
Score: 0.003
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Association of estramustine resistance in human prostatic carcinoma cells with modified patterns of tubulin expression. Biochem Pharmacol. 1998 Feb 01; 55(3):325-31.
Score: 0.003
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ATP-dependent uptake of natural product cytotoxic drugs by membrane vesicles establishes MRP as a broad specificity transporter. Proc Natl Acad Sci U S A. 1996 Jul 09; 93(14):6929-34.
Score: 0.002
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Cellular and in vitro transport of glutathione conjugates by MRP. Biochemistry. 1996 May 07; 35(18):5719-25.
Score: 0.002
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Isozyme-specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines. Cancer Chemother Pharmacol. 1996; 37(4):363-70.
Score: 0.002
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Glutathione and drug resistance. Cancer Invest. 1996; 14(2):158-68.
Score: 0.002
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Modulation of glutathione and related enzymes in reversal of resistance to anticancer drugs. Hematol Oncol Clin North Am. 1995 Apr; 9(2):383-96.
Score: 0.002
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Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid. Biochem Pharmacol. 1991 Sep 12; 42(7):1504-7.
Score: 0.002
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The spontaneous and glutathione S-transferase-mediated reaction of chlorambucil with glutathione. Cancer Commun. 1990; 2(8):279-85.
Score: 0.002
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Repair of DNA alkylation induced in L1210 leukemia and murine bone marrow by three chloroethylnitrosoureas. Cancer Res. 1982 Jul; 42(7):2605-8.
Score: 0.001
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Correlation of nitrosourea murine bone marrow toxicity with deoxyribonucleic acid alkylation and chromatin binding sites. Biochem Pharmacol. 1982 May 01; 31(9):1671-9.
Score: 0.001
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Modification of L1210 cell nuclear proteins by 1-methyl-1-nitrosourea and 1-methyl-3-nitro-1-nitrosoguanidine. Cancer Res. 1979 Mar; 39(3):923-8.
Score: 0.001
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Effects of cis-dichlorodiammine platinum (II) on DNA synthesis in kidney and other tissues of normal and tumour-bearing rats. Eur J Cancer (1965). 1976 Apr; 12(4):249-54.
Score: 0.001