Connection

Kenneth Tew to Antineoplastic Agents

Back to Details
This is a "connection" page, showing publications Kenneth Tew has written about Antineoplastic Agents.
Kenneth Tew
Connection Strength
4.032
Antineoplastic Agents
  1. Voltage-Dependent Anion Channels Influence Cytotoxicity of ME-344, a Therapeutic Isoflavone. J Pharmacol Exp Ther. 2020 08; 374(2):308-318.
    View in: PubMed
    Score: 0.408
  2. Pharmacology of ME-344, a novel cytotoxic isoflavone. Adv Cancer Res. 2019; 142:187-207.
    View in: PubMed
    Score: 0.373
  3. Glutathione-Associated Enzymes In Anticancer Drug Resistance. Cancer Res. 2016 Jan 01; 76(1):7-9.
    View in: PubMed
    Score: 0.300
  4. Redox platforms in cancer drug discovery and development. Curr Opin Chem Biol. 2011 Feb; 15(1):156-61.
    View in: PubMed
    Score: 0.210
  5. The impact of redox and thiol status on the bone marrow: Pharmacological intervention strategies. Pharmacol Ther. 2011 Feb; 129(2):172-84.
    View in: PubMed
    Score: 0.209
  6. Pharmacology of a mimetic of glutathione disulfide, NOV-002. Biomed Pharmacother. 2009 Feb; 63(2):75-8.
    View in: PubMed
    Score: 0.181
  7. Protein cysteine sulfinic acid reductase (sulfiredoxin) as a regulator of cell proliferation and drug response. Oncogene. 2008 Aug 21; 27(36):4877-87.
    View in: PubMed
    Score: 0.176
  8. NOV-002, a glutathione disulfide mimetic, as a modulator of cellular redox balance. Cancer Res. 2008 Apr 15; 68(8):2870-7.
    View in: PubMed
    Score: 0.176
  9. TLK-286: a novel glutathione S-transferase-activated prodrug. Expert Opin Investig Drugs. 2005 Aug; 14(8):1047-54.
    View in: PubMed
    Score: 0.146
  10. Glutathione S-transferases as regulators of kinase pathways and anticancer drug targets. Methods Enzymol. 2005; 401:287-307.
    View in: PubMed
    Score: 0.140
  11. Small molecule inhibition of hypoxia inducible factor-1alpha: a viable therapeutic approach? Mol Cancer Ther. 2004 Mar; 3(3):245-6.
    View in: PubMed
    Score: 0.132
  12. The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene. 2003 Oct 20; 22(47):7369-75.
    View in: PubMed
    Score: 0.129
  13. Cancer drugs, genetic variation and the glutathione-S-transferase gene family. Am J Pharmacogenomics. 2003; 3(3):157-72.
    View in: PubMed
    Score: 0.122
  14. Binding of the aminothiol WR-1065 to transcription factors influences cellular response to anticancer drugs. J Pharmacol Exp Ther. 2001 Jun; 297(3):1067-73.
    View in: PubMed
    Score: 0.109
  15. Cisplatin chemotherapy and renal function. Adv Cancer Res. 2021; 152:305-327.
    View in: PubMed
    Score: 0.108
  16. MYC Inhibition Depletes Cancer Stem-like Cells in Triple-Negative Breast Cancer. Cancer Res. 2017 12 01; 77(23):6641-6650.
    View in: PubMed
    Score: 0.084
  17. Commentary on "Proteasome Inhibitors: A Novel Class of Potent and Effective Antitumor Agents". Cancer Res. 2016 09 01; 76(17):4916-7.
    View in: PubMed
    Score: 0.078
  18. Glutathione-associated enzymes in the human cell lines of the National Cancer Institute Drug Screening Program. Mol Pharmacol. 1996 Jul; 50(1):149-59.
    View in: PubMed
    Score: 0.078
  19. Glutathione-associated enzymes in anticancer drug resistance. Cancer Res. 1994 Aug 15; 54(16):4313-20.
    View in: PubMed
    Score: 0.068
  20. Preclinical and clinical perspectives on the use of estramustine as an antimitotic drug. Pharmacol Ther. 1992 Dec; 56(3):323-39.
    View in: PubMed
    Score: 0.060
  21. Detoxification mechanisms and tumor cell resistance to anticancer drugs. Med Res Rev. 1991 Mar; 11(2):185-217.
    View in: PubMed
    Score: 0.054
  22. Regulatory functions of glutathione S-transferase P1-1 unrelated to detoxification. Drug Metab Rev. 2011 May; 43(2):179-93.
    View in: PubMed
    Score: 0.054
  23. Cytotoxicity and DNA damaging effects of a new nitrosourea, fotemustine, diethyl- 1-(3-(2-chloroethyl)-3-nitrosoureido) ethylphosphonate-S10036. Anticancer Res. 1989 Nov-Dec; 9(6):1617-22.
    View in: PubMed
    Score: 0.049
  24. Protective effects of a glutathione disulfide mimetic (NOV-002) against cisplatin induced kidney toxicity. Biomed Pharmacother. 2010 Jan; 64(1):73-6.
    View in: PubMed
    Score: 0.049
  25. Glutathione, glutathione S-transferases, and related redox enzymes in Adriamycin-resistant cell lines with a multidrug resistant phenotype. Cancer Commun. 1989; 1(2):133-9.
    View in: PubMed
    Score: 0.046
  26. Role of glutathione S-transferase Pi in cisplatin-induced nephrotoxicity. Biomed Pharmacother. 2009 Feb; 63(2):79-85.
    View in: PubMed
    Score: 0.045
  27. PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity. J Med Chem. 2006 Feb 09; 49(3):1157-64.
    View in: PubMed
    Score: 0.038
  28. Biochemical and cytotoxic properties of the isomeric forms of N,N'-bis[N-2-chloroethyl)-N-nitrosocarbamoyl] cystamine. Biochem Pharmacol. 1984 Aug 15; 33(16):2575-80.
    View in: PubMed
    Score: 0.034
  29. Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation. Br J Cancer. 2004 Jun 14; 90(12):2411-7.
    View in: PubMed
    Score: 0.034
  30. Cytotoxicity of estramustine, a steroid-nitrogen mustard derivative, through non-DNA targets. Mol Pharmacol. 1983 Sep; 24(2):324-8.
    View in: PubMed
    Score: 0.032
  31. Molecular modes of action of artesunate in tumor cell lines. Mol Pharmacol. 2003 Aug; 64(2):382-94.
    View in: PubMed
    Score: 0.032
  32. Selective cytotoxicity of haloethylnitrosoureas in a carcinoma cell line resistant to bifunctional nitrogen mustards. Mol Pharmacol. 1982 May; 21(3):729-38.
    View in: PubMed
    Score: 0.029
  33. Cellular thiols and reactive oxygen species in drug-induced apoptosis. J Pharmacol Exp Ther. 2001 Jan; 296(1):1-6.
    View in: PubMed
    Score: 0.026
  34. Double high-dose chemotherapy with stem cell rescue (HD-SCR) in patients with breast cancer - effect of sequence. Cancer Chemother Pharmacol. 2000; 45(3):239-46.
    View in: PubMed
    Score: 0.025
  35. Coordinate changes in expression of protective genes in drug-resistant cells. Chem Biol Interact. 1998 Apr 24; 111-112:199-211.
    View in: PubMed
    Score: 0.022
  36. Selenocompounds in Cancer Therapy: An Overview. Adv Cancer Res. 2017; 136:259-302.
    View in: PubMed
    Score: 0.021
  37. ATP-dependent uptake of natural product cytotoxic drugs by membrane vesicles establishes MRP as a broad specificity transporter. Proc Natl Acad Sci U S A. 1996 Jul 09; 93(14):6929-34.
    View in: PubMed
    Score: 0.019
  38. Increase of beta(III)- and beta(IVa)-tubulin isotopes in human prostate carcinoma cells as a result of estramustine resistance. Cancer Res. 1996 Jun 01; 56(11):2584-9.
    View in: PubMed
    Score: 0.019
  39. Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells. Mol Pharm. 2016 06 06; 13(6):2010-25.
    View in: PubMed
    Score: 0.019
  40. Isozyme-specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines. Cancer Chemother Pharmacol. 1996; 37(4):363-70.
    View in: PubMed
    Score: 0.019
  41. Glutathione S-transferases. Cancer Treat Res. 1996; 87:83-122.
    View in: PubMed
    Score: 0.019
  42. Glyoxalase I in detoxification: studies using a glyoxalase I transfectant cell line. Biochem J. 1995 Jul 01; 309 ( Pt 1):127-31.
    View in: PubMed
    Score: 0.018
  43. Modulation of glutathione and related enzymes in reversal of resistance to anticancer drugs. Hematol Oncol Clin North Am. 1995 Apr; 9(2):383-96.
    View in: PubMed
    Score: 0.018
  44. Glutathione-S-transferase pi as a determinant of drug resistance in transfectant cell lines. J Biol Chem. 1990 Mar 15; 265(8):4296-301.
    View in: PubMed
    Score: 0.013
  45. Mechanism of action of 2-haloethylnitrosoureas on deoxyribonucleic acid. Pathways of aqueous decomposition and pharmacological characteristics of new anticancer disulfide-linked nitrosoureas. Biochem Pharmacol. 1985 Apr 01; 34(7):1015-24.
    View in: PubMed
    Score: 0.009
  46. Cellular and in vitro transport of glutathione conjugates by MRP. Biochemistry. 1996 May 07; 35(18):5719-25.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.