Connection

Kenneth Tew to Glutathione Transferase

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This is a "connection" page, showing publications Kenneth Tew has written about Glutathione Transferase.
Kenneth Tew
Connection Strength
8.332
Glutathione Transferase
  1. Development of Telintra as an Inhibitor of Glutathione S-Transferase P. Handb Exp Pharmacol. 2021; 264:71-91.
    View in: PubMed
    Score: 0.662
  2. Glutathione S-Transferase P-Mediated Protein S-Glutathionylation of Resident Endoplasmic Reticulum Proteins Influences Sensitivity to Drug-Induced Unfolded Protein Response. Antioxid Redox Signal. 2017 02 20; 26(6):247-261.
    View in: PubMed
    Score: 0.475
  3. Glutathione S-transferase P influences redox and migration pathways in bone marrow. PLoS One. 2014; 9(9):e107478.
    View in: PubMed
    Score: 0.428
  4. Glutathione-s-transferases as determinants of cell survival and death. Antioxid Redox Signal. 2012 Dec 15; 17(12):1728-37.
    View in: PubMed
    Score: 0.366
  5. The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer. Free Radic Biol Med. 2011 Jul 15; 51(2):299-313.
    View in: PubMed
    Score: 0.338
  6. Redox in redux: Emergent roles for glutathione S-transferase P (GSTP) in regulation of cell signaling and S-glutathionylation. Biochem Pharmacol. 2007 May 01; 73(9):1257-69.
    View in: PubMed
    Score: 0.247
  7. Glutathione S-transferase polymorphisms: cancer incidence and therapy. Oncogene. 2006 Mar 13; 25(11):1639-48.
    View in: PubMed
    Score: 0.237
  8. TLK-286: a novel glutathione S-transferase-activated prodrug. Expert Opin Investig Drugs. 2005 Aug; 14(8):1047-54.
    View in: PubMed
    Score: 0.227
  9. Influence of glutathione S-transferase pi and p53 expression on tumor frequency and spectrum in mice. Int J Cancer. 2005 Jan 01; 113(1):29-35.
    View in: PubMed
    Score: 0.218
  10. Glutathione S-transferases as regulators of kinase pathways and anticancer drug targets. Methods Enzymol. 2005; 401:287-307.
    View in: PubMed
    Score: 0.218
  11. Tumor cell responses to a novel glutathione S-transferase-activated nitric oxide-releasing prodrug. Mol Pharmacol. 2004 May; 65(5):1070-9.
    View in: PubMed
    Score: 0.208
  12. Increased myeloproliferation in glutathione S-transferase pi-deficient mice is associated with a deregulation of JNK and Janus kinase/STAT pathways. J Biol Chem. 2004 Mar 05; 279(10):8608-16.
    View in: PubMed
    Score: 0.203
  13. The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene. 2003 Oct 20; 22(47):7369-75.
    View in: PubMed
    Score: 0.201
  14. Resistance to phorbol 12-myristate 13-acetate-induced cell growth arrest in an HL60 cell line chronically exposed to a glutathione S-transferase pi inhibitor. Biochem Pharmacol. 2003 May 15; 65(10):1611-22.
    View in: PubMed
    Score: 0.195
  15. Cancer drugs, genetic variation and the glutathione-S-transferase gene family. Am J Pharmacogenomics. 2003; 3(3):157-72.
    View in: PubMed
    Score: 0.190
  16. Efficacy of a glutathione S-transferase pi-activated prodrug in platinum-resistant ovarian cancer cells. Mol Cancer Ther. 2002 Oct; 1(12):1089-95.
    View in: PubMed
    Score: 0.187
  17. Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus. J Biol Chem. 2001 Jun 15; 276(24):20999-1003.
    View in: PubMed
    Score: 0.168
  18. The influence of coordinate overexpression of glutathione phase II detoxification gene products on drug resistance. J Pharmacol Exp Ther. 2000 Aug; 294(2):480-7.
    View in: PubMed
    Score: 0.161
  19. Cellular response to a glutathione S-transferase P1-1 activated prodrug. Mol Pharmacol. 2000 Jul; 58(1):167-74.
    View in: PubMed
    Score: 0.160
  20. Impact of dietary supplement of Crassostrea gigas extract (JCOE) on glutathione levels and glutathione S-transferase activity in rat tissues. In Vivo. 1998 May-Jun; 12(3):299-303.
    View in: PubMed
    Score: 0.138
  21. MGST1, a GSH transferase/peroxidase essential for development and hematopoietic stem cell differentiation. Redox Biol. 2018 07; 17:171-179.
    View in: PubMed
    Score: 0.137
  22. Importance of glutathione and associated enzymes in drug response. Oncol Res. 1997; 9(6-7):295-302.
    View in: PubMed
    Score: 0.125
  23. Glutathione-associated enzymes in the human cell lines of the National Cancer Institute Drug Screening Program. Mol Pharmacol. 1996 Jul; 50(1):149-59.
    View in: PubMed
    Score: 0.121
  24. Adaptive response to glutathione S-transferase inhibitors. Br J Cancer Suppl. 1996 Jul; 27:S93-8.
    View in: PubMed
    Score: 0.121
  25. Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells. Mol Pharm. 2016 06 06; 13(6):2010-25.
    View in: PubMed
    Score: 0.120
  26. Glutathione S-transferases. Cancer Treat Res. 1996; 87:83-122.
    View in: PubMed
    Score: 0.117
  27. Influence of ethacrynic acid on glutathione S-transferase pi transcript and protein half-lives in human colon cancer cells. Biochem Pharmacol. 1995 Oct 12; 50(8):1233-8.
    View in: PubMed
    Score: 0.115
  28. Modulation of detoxification gene expression in human colon HT29 cells by glutathione-S-transferase inhibitors. Mol Pharmacol. 1995 Oct; 48(4):639-47.
    View in: PubMed
    Score: 0.115
  29. Glutathione-associated enzymes in anticancer drug resistance. Cancer Res. 1994 Aug 15; 54(16):4313-20.
    View in: PubMed
    Score: 0.106
  30. Causes and consequences of cysteine S-glutathionylation. J Biol Chem. 2013 Sep 13; 288(37):26497-504.
    View in: PubMed
    Score: 0.099
  31. Time course of glutathione S-transferase elevation in Walker mammary carcinoma cells following chlorambucil exposure. Biochem Pharmacol. 1993 Feb 09; 45(3):683-90.
    View in: PubMed
    Score: 0.096
  32. Allelic variants of glutathione S-transferase P1-1 differentially mediate the peroxidase function of peroxiredoxin VI and alter membrane lipid peroxidation. Free Radic Biol Med. 2013 Jan; 54:62-70.
    View in: PubMed
    Score: 0.094
  33. Heterogeneity of glutathione S-transferase enzyme and gene expression in ovarian carcinoma. Pharmacogenetics. 1992 Apr; 2(2):63-72.
    View in: PubMed
    Score: 0.090
  34. Increased levels of glutathione S-transferase pi transcript as a mechanism of resistance to ethacrynic acid. Biochem J. 1992 Jan 01; 281 ( Pt 1):219-24.
    View in: PubMed
    Score: 0.089
  35. Immunohistochemical localization of glutathione S-transferases alpha, mu, and pi in normal tissue and carcinomas from human colon. Carcinogenesis. 1991 Dec; 12(12):2383-7.
    View in: PubMed
    Score: 0.088
  36. Contribution of patient history to the glutathione S-transferase activity of human lung, breast and colon tissue. Carcinogenesis. 1991 Oct; 12(10):1957-61.
    View in: PubMed
    Score: 0.087
  37. Evidence for a glycoconjugate form of glutathione S-transferase pI. Int J Pept Protein Res. 1991 Jun; 37(6):565-71.
    View in: PubMed
    Score: 0.085
  38. Glutathione S-transferases in normal and malignant human colon tissue. Biochim Biophys Acta. 1991 Apr 15; 1096(3):209-16.
    View in: PubMed
    Score: 0.084
  39. Characterization of glutathione S-transferase expression in lymphocytes from chronic lymphocytic leukemia patients. Cancer Res. 1990 Jun 15; 50(12):3562-8.
    View in: PubMed
    Score: 0.080
  40. Cellular resistance to a nitric oxide releasing glutathione S-transferase P-activated prodrug, PABA/NO. Invest New Drugs. 2011 Oct; 29(5):719-29.
    View in: PubMed
    Score: 0.078
  41. Glutathione-S-transferase pi as a determinant of drug resistance in transfectant cell lines. J Biol Chem. 1990 Mar 15; 265(8):4296-301.
    View in: PubMed
    Score: 0.078
  42. Identification of a glutathione S-transferase associated with microsomes of tumor cells resistant to nitrogen mustards. Biochem Pharmacol. 1989 Jun 15; 38(12):1915-21.
    View in: PubMed
    Score: 0.074
  43. Glutathione, glutathione S-transferases, and related redox enzymes in Adriamycin-resistant cell lines with a multidrug resistant phenotype. Cancer Commun. 1989; 1(2):133-9.
    View in: PubMed
    Score: 0.072
  44. Purification of glutathione S-transferases from rat liver and Walker 256 mammary carcinoma cells by high-performance liquid chromatography and a glutathione affinity column. J Chromatogr. 1988 Dec 29; 434(1):83-93.
    View in: PubMed
    Score: 0.072
  45. Glutathione S-transferases in human prostate. Biochim Biophys Acta. 1987 Oct 08; 926(1):8-15.
    View in: PubMed
    Score: 0.066
  46. Glutathione S-transferases in nitrogen mustard-resistant and -sensitive cell lines. Mol Pharmacol. 1987 Jun; 31(6):575-8.
    View in: PubMed
    Score: 0.065
  47. Relationship of glutathione depletion and inhibition of glutathione-S-transferase activity to the antimitotic properties of estramustine. Cancer Treat Rep. 1986 Jun; 70(6):715-20.
    View in: PubMed
    Score: 0.060
  48. Increased glutathione-S-transferase activity in a cell line with acquired resistance to nitrogen mustards. Cancer Treat Rep. 1985 Jun; 69(6):677-82.
    View in: PubMed
    Score: 0.056
  49. Glutathione and ABC transporters as determinants of sensitivity to oxidative and nitrosative stress. J Nutr. 2004 Nov; 134(11):3205S-3206S.
    View in: PubMed
    Score: 0.054
  50. Sensitivity and fidelity of DNA microarray improved with integration of Amplified Differential Gene Expression (ADGE). BMC Genomics. 2003 Jul 14; 4(1):28.
    View in: PubMed
    Score: 0.049
  51. Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases. Cancer Res. 2000 Aug 01; 60(15):4053-7.
    View in: PubMed
    Score: 0.040
  52. Regulation of JNK signaling by GSTp. EMBO J. 1999 Mar 01; 18(5):1321-34.
    View in: PubMed
    Score: 0.036
  53. Tumor efficacy and bone marrow-sparing properties of TER286, a cytotoxin activated by glutathione S-transferase. Cancer Res. 1998 Jun 15; 58(12):2568-75.
    View in: PubMed
    Score: 0.035
  54. The antioxidant effects of Crassostrea gigas extract (JCOE) in human volunteers. In Vivo. 1998 May-Jun; 12(3):305-9.
    View in: PubMed
    Score: 0.034
  55. Coordinate changes in expression of protective genes in drug-resistant cells. Chem Biol Interact. 1998 Apr 24; 111-112:199-211.
    View in: PubMed
    Score: 0.034
  56. Glutathione and related enzymes in multidrug resistance. Eur J Cancer. 1996 Jun; 32A(6):967-78.
    View in: PubMed
    Score: 0.030
  57. Isozyme-specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines. Cancer Chemother Pharmacol. 1996; 37(4):363-70.
    View in: PubMed
    Score: 0.029
  58. Increased glutathione expression in cells induced by Crassostera gigas extract (JCOE). Biomed Pharmacother. 1996; 50(3-4):149-53.
    View in: PubMed
    Score: 0.029
  59. Modulation of glutathione and related enzymes in reversal of resistance to anticancer drugs. Hematol Oncol Clin North Am. 1995 Apr; 9(2):383-96.
    View in: PubMed
    Score: 0.028
  60. Phase I study of thiotepa in combination with the glutathione transferase inhibitor ethacrynic acid. Cancer Res. 1991 Nov 15; 51(22):6059-65.
    View in: PubMed
    Score: 0.022
  61. Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid. Biochem Pharmacol. 1991 Sep 12; 42(7):1504-7.
    View in: PubMed
    Score: 0.022
  62. The spontaneous and glutathione S-transferase-mediated reaction of chlorambucil with glutathione. Cancer Commun. 1990; 2(8):279-85.
    View in: PubMed
    Score: 0.019
  63. Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines. Cancer Res. 1988 Jul 01; 48(13):3622-5.
    View in: PubMed
    Score: 0.017
  64. The importance of glutathione in human disease. Biomed Pharmacother. 2003 May-Jun; 57(3-4):145-55.
    View in: PubMed
    Score: 0.012
  65. Role of redox potential and reactive oxygen species in stress signaling. Oncogene. 1999 Nov 01; 18(45):6104-11.
    View in: PubMed
    Score: 0.010
  66. Glutathione and drug resistance. Cancer Invest. 1996; 14(2):158-68.
    View in: PubMed
    Score: 0.007
  67. Determinants of drug response in a cisplatin-resistant human lung cancer cell line. Jpn J Cancer Res. 1990 May; 81(5):527-35.
    View in: PubMed
    Score: 0.005
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