Kenneth Tew to Humans
This is a "connection" page, showing publications Kenneth Tew has written about Humans.
Connection Strength
1.279
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Reductive stress in cancer. Adv Cancer Res. 2021; 152:383-413.
Score: 0.029
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Development of Telintra as an Inhibitor of Glutathione S-Transferase P. Handb Exp Pharmacol. 2021; 264:71-91.
Score: 0.028
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Oxidative Stress in Cancer. Cancer Cell. 2020 08 10; 38(2):167-197.
Score: 0.027
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Voltage-Dependent Anion Channels Influence Cytotoxicity of ME-344, a Therapeutic Isoflavone. J Pharmacol Exp Ther. 2020 08; 374(2):308-318.
Score: 0.027
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S-Glutathionylated Serine Proteinase Inhibitors as Biomarkers for Radiation Exposure in Prostate Cancer Patients. Sci Rep. 2019 09 24; 9(1):13792.
Score: 0.026
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Isoflavone ME-344 Disrupts Redox Homeostasis and Mitochondrial Function by Targeting Heme Oxygenase 1. Cancer Res. 2019 08 15; 79(16):4072-4085.
Score: 0.025
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Racial disparities, cancer and response to oxidative stress. Adv Cancer Res. 2019; 144:343-383.
Score: 0.025
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Pharmacology of ME-344, a novel cytotoxic isoflavone. Adv Cancer Res. 2019; 142:187-207.
Score: 0.025
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An evolving understanding of the S-glutathionylation cycle in pathways of redox regulation. Free Radic Biol Med. 2018 05 20; 120:204-216.
Score: 0.023
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ATP-binding cassette transporter-2 (ABCA2) as a therapeutic target. Biochem Pharmacol. 2018 05; 151:188-200.
Score: 0.023
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Preface. Adv Cancer Res. 2017; 136:xi-xiv.
Score: 0.021
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Redox Signaling and Bioenergetics Influence Lung Cancer Cell Line Sensitivity to the Isoflavone ME-344. J Pharmacol Exp Ther. 2016 08; 358(2):199-208.
Score: 0.020
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Glutathione-Associated Enzymes In Anticancer Drug Resistance. Cancer Res. 2016 Jan 01; 76(1):7-9.
Score: 0.020
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Oxidative stress, redox regulation and diseases of cellular differentiation. Biochim Biophys Acta. 2015 Aug; 1850(8):1607-21.
Score: 0.018
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Causes and consequences of cysteine S-glutathionylation. J Biol Chem. 2013 Sep 13; 288(37):26497-504.
Score: 0.017
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Sulfiredoxin redox-sensitive interaction with S100A4 and non-muscle myosin IIA regulates cancer cell motility. Biochemistry. 2012 Oct 02; 51(39):7740-54.
Score: 0.016
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Glutathione-s-transferases as determinants of cell survival and death. Antioxid Redox Signal. 2012 Dec 15; 17(12):1728-37.
Score: 0.015
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S-glutathionylated serine proteinase inhibitors as plasma biomarkers in assessing response to redox-modulating drugs. Cancer Res. 2012 May 01; 72(9):2383-93.
Score: 0.015
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NrF2 /Keap1 as gatekeepers of redox homeostasis ? do they prevent or cause cancer? Pigment Cell Melanoma Res. 2011 Dec; 24(6):1078-9.
Score: 0.015
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Drug resistance in cancer. Editorial. Biochem Pharmacol. 2012 Apr 15; 83(8):985-6.
Score: 0.015
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The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer. Free Radic Biol Med. 2011 Jul 15; 51(2):299-313.
Score: 0.014
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Regulatory functions of glutathione S-transferase P1-1 unrelated to detoxification. Drug Metab Rev. 2011 May; 43(2):179-93.
Score: 0.014
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Diazeniumdiolate mediated nitrosative stress alters nitric oxide homeostasis through intracellular calcium and S-glutathionylation of nitric oxide synthetase. PLoS One. 2010 Nov 30; 5(11):e14151.
Score: 0.014
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Redox platforms in cancer drug discovery and development. Curr Opin Chem Biol. 2011 Feb; 15(1):156-61.
Score: 0.014
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The impact of redox and thiol status on the bone marrow: Pharmacological intervention strategies. Pharmacol Ther. 2011 Feb; 129(2):172-84.
Score: 0.014
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Redox metabolism and malignancy. Curr Opin Pharmacol. 2010 Aug; 10(4):362-8.
Score: 0.013
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Nitrosative stress-induced s-glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein response. Cancer Res. 2009 Oct 01; 69(19):7626-34.
Score: 0.013
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Novel role for glutathione S-transferase pi. Regulator of protein S-Glutathionylation following oxidative and nitrosative stress. J Biol Chem. 2009 Jan 02; 284(1):436-445.
Score: 0.012
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Pharmacology of a mimetic of glutathione disulfide, NOV-002. Biomed Pharmacother. 2009 Feb; 63(2):75-8.
Score: 0.012
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NOV-002, a mimetic of glutathione disulfide. Expert Opin Investig Drugs. 2008 Jul; 17(7):1075-83.
Score: 0.012
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Protein cysteine sulfinic acid reductase (sulfiredoxin) as a regulator of cell proliferation and drug response. Oncogene. 2008 Aug 21; 27(36):4877-87.
Score: 0.012
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NOV-002, a glutathione disulfide mimetic, as a modulator of cellular redox balance. Cancer Res. 2008 Apr 15; 68(8):2870-7.
Score: 0.012
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ABCA2 as a therapeutic target in cancer and nervous system disorders. Expert Opin Ther Targets. 2008 Apr; 12(4):491-504.
Score: 0.012
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Redox in redux: Emergent roles for glutathione S-transferase P (GSTP) in regulation of cell signaling and S-glutathionylation. Biochem Pharmacol. 2007 May 01; 73(9):1257-69.
Score: 0.010
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A novel role for human sulfiredoxin in the reversal of glutathionylation. Cancer Res. 2006 Jul 01; 66(13):6800-6.
Score: 0.010
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Glutathione S-transferase polymorphisms: cancer incidence and therapy. Oncogene. 2006 Mar 13; 25(11):1639-48.
Score: 0.010
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A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins. Mol Pharmacol. 2006 Feb; 69(2):501-8.
Score: 0.010
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Evaluation of lipophilins as determinants of tumor cell response to estramustine. J Pharmacol Exp Ther. 2005 Dec; 315(3):1158-62.
Score: 0.010
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TLK-286: a novel glutathione S-transferase-activated prodrug. Expert Opin Investig Drugs. 2005 Aug; 14(8):1047-54.
Score: 0.010
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Characterization of the ATPase activity of human ATP-binding cassette transporter-2 (ABCA2). In Vivo. 2005 Jul-Aug; 19(4):657-60.
Score: 0.010
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Glutathione S-transferases as regulators of kinase pathways and anticancer drug targets. Methods Enzymol. 2005; 401:287-307.
Score: 0.009
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Glutathione and ABC transporters as determinants of sensitivity to oxidative and nitrosative stress. J Nutr. 2004 Nov; 134(11):3205S-3206S.
Score: 0.009
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Human ATP-binding cassette transporter-2 (ABCA2) positively regulates low-density lipoprotein receptor expression and negatively regulates cholesterol esterification in Chinese hamster ovary cells. Biochim Biophys Acta. 2004 Jul 05; 1683(1-3):89-100.
Score: 0.009
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Association of ABCA2 expression with determinants of Alzheimer's disease. FASEB J. 2004 Jul; 18(10):1129-31.
Score: 0.009
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Identification of a novel first exon of the human ABCA2 transporter gene encoding a unique N-terminus. Biochim Biophys Acta. 2004 Apr 16; 1678(1):22-32.
Score: 0.009
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Organosulfur compounds from alliaceae in the prevention of human pathologies. Biomed Pharmacother. 2004 Apr; 58(3):183-93.
Score: 0.009
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The role of carotenoids in the prevention of human pathologies. Biomed Pharmacother. 2004 Mar; 58(2):100-10.
Score: 0.009
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Small molecule inhibition of hypoxia inducible factor-1alpha: a viable therapeutic approach? Mol Cancer Ther. 2004 Mar; 3(3):245-6.
Score: 0.009
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Amplified differential gene expression microarray. Methods Mol Biol. 2004; 258:95-106.
Score: 0.009
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Trace elements in human physiology and pathology. Copper. Biomed Pharmacother. 2003 Nov; 57(9):386-98.
Score: 0.009
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Trace elements in human physiology and pathology: zinc and metallothioneins. Biomed Pharmacother. 2003 Nov; 57(9):399-411.
Score: 0.009
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The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene. 2003 Oct 20; 22(47):7369-75.
Score: 0.009
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Phytosterols in the prevention of human pathologies. Biomed Pharmacother. 2003 Oct; 57(8):321-5.
Score: 0.008
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Sensitivity and fidelity of DNA microarray improved with integration of Amplified Differential Gene Expression (ADGE). BMC Genomics. 2003 Jul 14; 4(1):28.
Score: 0.008
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Resistance to phorbol 12-myristate 13-acetate-induced cell growth arrest in an HL60 cell line chronically exposed to a glutathione S-transferase pi inhibitor. Biochem Pharmacol. 2003 May 15; 65(10):1611-22.
Score: 0.008
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The antioxidant role of selenium and seleno-compounds. Biomed Pharmacother. 2003 May-Jun; 57(3-4):134-44.
Score: 0.008
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Reciprocal regulation of expression of the human adenosine 5'-triphosphate binding cassette, sub-family A, transporter 2 (ABCA2) promoter by the early growth response-1 (EGR-1) and Sp-family transcription factors. Nucleic Acids Res. 2003 Feb 01; 31(3):1097-107.
Score: 0.008
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Cancer drugs, genetic variation and the glutathione-S-transferase gene family. Am J Pharmacogenomics. 2003; 3(3):157-72.
Score: 0.008
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Integration of amplified differential gene expression (ADGE) and DNA microarray. IUBMB Life. 2002 Dec; 54(6):335-8.
Score: 0.008
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I. Arginine. Biomed Pharmacother. 2002 Nov; 56(9):439-45.
Score: 0.008
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II. Glutamine and glutamate. Biomed Pharmacother. 2002 Nov; 56(9):446-57.
Score: 0.008
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Efficacy of a glutathione S-transferase pi-activated prodrug in platinum-resistant ovarian cancer cells. Mol Cancer Ther. 2002 Oct; 1(12):1089-95.
Score: 0.008
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Estrogens and environmental estrogens. Biomed Pharmacother. 2002 Feb; 56(1):36-44.
Score: 0.008
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Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia. J Clin Invest. 2021 08 16; 131(16).
Score: 0.007
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Binding of the aminothiol WR-1065 to transcription factors influences cellular response to anticancer drugs. J Pharmacol Exp Ther. 2001 Jun; 297(3):1067-73.
Score: 0.007
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Gene expression profiling using a novel method: amplified differential gene expression (ADGE). Nucleic Acids Res. 2001 May 15; 29(10):E46.
Score: 0.007
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Cisplatin chemotherapy and renal function. Adv Cancer Res. 2021; 152:305-327.
Score: 0.007
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Nrf2 inhibition sensitizes breast cancer stem cells to ionizing radiation via suppressing DNA repair. Free Radic Biol Med. 2021 06; 169:238-247.
Score: 0.007
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Cloning and characterization of human adenosine 5'-triphosphate-binding cassette, sub-family A, transporter 2 (ABCA2). Cancer Res. 2001 Apr 15; 61(8):3339-47.
Score: 0.007
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Cellular thiols and reactive oxygen species in drug-induced apoptosis. J Pharmacol Exp Ther. 2001 Jan; 296(1):1-6.
Score: 0.007
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Altered redox regulation and S-glutathionylation of BiP contribute to bortezomib resistance in multiple myeloma. Free Radic Biol Med. 2020 11 20; 160:755-767.
Score: 0.007
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The influence of coordinate overexpression of glutathione phase II detoxification gene products on drug resistance. J Pharmacol Exp Ther. 2000 Aug; 294(2):480-7.
Score: 0.007
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Cellular response to a glutathione S-transferase P1-1 activated prodrug. Mol Pharmacol. 2000 Jul; 58(1):167-74.
Score: 0.007
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Glutathione peptidomimetic drug modulator of multidrug resistance-associated protein. J Pharmacol Exp Ther. 1999 Dec; 291(3):1348-55.
Score: 0.006
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Genomic sequence of human glyoxalase-I: analysis of promoter activity and its regulation. Gene. 1999 Nov 15; 240(1):149-55.
Score: 0.006
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Nrf2-modulation by seleno-hormetic agents and its potential for radiation protection. Biofactors. 2020 Mar; 46(2):239-245.
Score: 0.006
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Glutathione conjugate interactions with DNA-dependent protein kinase. J Pharmacol Exp Ther. 1999 Sep; 290(3):1101-6.
Score: 0.006
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Oxidative stress induces senescence in breast cancer stem cells. Biochem Biophys Res Commun. 2019 07 05; 514(4):1204-1209.
Score: 0.006
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A seleno-hormetine protects bone marrow hematopoietic cells against ionizing radiation-induced toxicities. PLoS One. 2019; 14(4):e0205626.
Score: 0.006
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Increased expression of DNA-dependent protein kinase confers resistance to adriamycin. Biochim Biophys Acta. 1998 Jul 23; 1381(2):131-8.
Score: 0.006
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The antioxidant effects of Crassostrea gigas extract (JCOE) in human volunteers. In Vivo. 1998 May-Jun; 12(3):305-9.
Score: 0.006
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Coordinate changes in expression of protective genes in drug-resistant cells. Chem Biol Interact. 1998 Apr 24; 111-112:199-211.
Score: 0.006
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Amplification of the ATP-binding cassette 2 transporter gene is functionally linked with enhanced efflux of estramustine in ovarian carcinoma cells. Cancer Res. 1998 Apr 01; 58(7):1332-7.
Score: 0.006
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Selenocompounds in Cancer Therapy: An Overview. Adv Cancer Res. 2017; 136:259-302.
Score: 0.006
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MYC Inhibition Depletes Cancer Stem-like Cells in Triple-Negative Breast Cancer. Cancer Res. 2017 12 01; 77(23):6641-6650.
Score: 0.006
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Interaction of estramustine with tubulin isotypes. Biochemistry. 1997 Jan 28; 36(4):871-8.
Score: 0.005
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Importance of glutathione and associated enzymes in drug response. Oncol Res. 1997; 9(6-7):295-302.
Score: 0.005
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Promoter analysis of a human dihydrodiol dehydrogenase. Biochem Biophys Res Commun. 1996 Nov 12; 228(2):524-9.
Score: 0.005
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Glutathione-associated enzymes in the human cell lines of the National Cancer Institute Drug Screening Program. Mol Pharmacol. 1996 Jul; 50(1):149-59.
Score: 0.005
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Adaptive response to glutathione S-transferase inhibitors. Br J Cancer Suppl. 1996 Jul; 27:S93-8.
Score: 0.005
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Glutathione and related enzymes in multidrug resistance. Eur J Cancer. 1996 Jun; 32A(6):967-78.
Score: 0.005
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Effects of chronic ethacrynic acid exposure on glutathione conjugation and MRP expression in human colon tumor cells. Biochem Biophys Res Commun. 1996 May 06; 222(1):111-5.
Score: 0.005
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Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells. Mol Pharm. 2016 06 06; 13(6):2010-25.
Score: 0.005
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Glutathione S-transferase pi modulates NF-?B activation and pro-inflammatory responses in lung epithelial cells. Redox Biol. 2016 08; 8:375-82.
Score: 0.005
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Adverse Outcomes Associated with Cigarette Smoke Radicals Related to Damage to Protein-disulfide Isomerase. J Biol Chem. 2016 Feb 26; 291(9):4763-78.
Score: 0.005
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Increased glutathione expression in cells induced by Crassostera gigas extract (JCOE). Biomed Pharmacother. 1996; 50(3-4):149-53.
Score: 0.005
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Glutathione S-transferases. Cancer Treat Res. 1996; 87:83-122.
Score: 0.005
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Influence of ethacrynic acid on glutathione S-transferase pi transcript and protein half-lives in human colon cancer cells. Biochem Pharmacol. 1995 Oct 12; 50(8):1233-8.
Score: 0.005
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Modulation of detoxification gene expression in human colon HT29 cells by glutathione-S-transferase inhibitors. Mol Pharmacol. 1995 Oct; 48(4):639-47.
Score: 0.005
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Glyoxalase I in detoxification: studies using a glyoxalase I transfectant cell line. Biochem J. 1995 Jul 01; 309 ( Pt 1):127-31.
Score: 0.005
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Modulation of P-glycoprotein activity by estramustine is limited by binding to plasma proteins. Cancer. 1995 May 15; 75(10):2597-604.
Score: 0.005
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Interaction of an estramustine photoaffinity analogue with cytoskeletal proteins in prostate carcinoma cells. Mol Pharmacol. 1994 Nov; 46(5):866-72.
Score: 0.005
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Reaction kinetics and targeting to cellular glutathione S-transferase of the glutathione peroxidase mimetic PhSeZnCl and its D,L-polylactide microparticle formulation. Free Radic Biol Med. 2015 Jan; 78:56-65.
Score: 0.005
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Glutathione-associated enzymes in anticancer drug resistance. Cancer Res. 1994 Aug 15; 54(16):4313-20.
Score: 0.005
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cDNA and deduced amino acid sequences of a human colon dihydrodiol dehydrogenase. Biochim Biophys Acta. 1994 Jun 28; 1186(1-2):129-32.
Score: 0.004
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Regulation of human dihydrodiol dehydrogenase by Michael acceptor xenobiotics. J Biol Chem. 1994 Jun 03; 269(22):15558-62.
Score: 0.004
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P-glycoprotein binding and modulation of the multidrug-resistant phenotype by estramustine. J Natl Cancer Inst. 1994 May 04; 86(9):688-94.
Score: 0.004
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Peroxiredoxin VI oxidation in cerebrospinal fluid correlates with traumatic brain injury outcome. Free Radic Biol Med. 2014 Jul; 72:210-21.
Score: 0.004
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Pleiotropic functions of glutathione S-transferase P. Adv Cancer Res. 2014; 122:143-75.
Score: 0.004
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Analysis of glyoxalase-I from normal and tumor tissue from human colon. Biochim Biophys Acta. 1993 Oct 20; 1182(3):311-6.
Score: 0.004
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Overproduction of a 37.5-kDa cytosolic protein structurally related to prostaglandin F synthase in ethacrynic acid-resistant human colon cells. Mol Pharmacol. 1993 Jun; 43(6):845-53.
Score: 0.004
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Cloning and characterization of human colon glyoxalase-I. J Biol Chem. 1993 Mar 15; 268(8):5661-7.
Score: 0.004
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Preclinical and clinical perspectives on the use of estramustine as an antimitotic drug. Pharmacol Ther. 1992 Dec; 56(3):323-39.
Score: 0.004
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Allelic variants of glutathione S-transferase P1-1 differentially mediate the peroxidase function of peroxiredoxin VI and alter membrane lipid peroxidation. Free Radic Biol Med. 2013 Jan; 54:62-70.
Score: 0.004
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Combined antimicrotubule activity of estramustine and taxol in human prostatic carcinoma cell lines. Cancer Res. 1992 Aug 15; 52(16):4433-40.
Score: 0.004
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Developmental expression of orphan G protein-coupled receptor 50 in the mouse brain. ACS Chem Neurosci. 2012 Jun 20; 3(6):459-72.
Score: 0.004
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Heterogeneity of glutathione S-transferase enzyme and gene expression in ovarian carcinoma. Pharmacogenetics. 1992 Apr; 2(2):63-72.
Score: 0.004
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Increased levels of glutathione S-transferase pi transcript as a mechanism of resistance to ethacrynic acid. Biochem J. 1992 Jan 01; 281 ( Pt 1):219-24.
Score: 0.004
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Immunohistochemical localization of glutathione S-transferases alpha, mu, and pi in normal tissue and carcinomas from human colon. Carcinogenesis. 1991 Dec; 12(12):2383-7.
Score: 0.004
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Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-? production by altering Nicastrin maturation and intracellular localization. J Biol Chem. 2012 Jan 06; 287(2):1100-11.
Score: 0.004
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Contribution of patient history to the glutathione S-transferase activity of human lung, breast and colon tissue. Carcinogenesis. 1991 Oct; 12(10):1957-61.
Score: 0.004
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Resistance to the antimitotic drug estramustine is distinct from the multidrug resistant phenotype. Br J Cancer. 1991 Aug; 64(2):267-73.
Score: 0.004
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Evidence for a glycoconjugate form of glutathione S-transferase pI. Int J Pept Protein Res. 1991 Jun; 37(6):565-71.
Score: 0.004
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S-glutathionylation: from molecular mechanisms to health outcomes. Antioxid Redox Signal. 2011 Jul 01; 15(1):233-70.
Score: 0.004
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Glutathione S-transferases in normal and malignant human colon tissue. Biochim Biophys Acta. 1991 Apr 15; 1096(3):209-16.
Score: 0.004
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The effects of estramustine on metaphase and anaphase in DU 145 prostatic carcinoma cells. Eur J Cell Biol. 1991 Apr; 54(2):268-76.
Score: 0.004
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Detoxification mechanisms and tumor cell resistance to anticancer drugs. Med Res Rev. 1991 Mar; 11(2):185-217.
Score: 0.004
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Mechanism based chemotherapy for prostate cancer. Cancer Surv. 1991; 11:239-54.
Score: 0.004
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Characterization of glutathione S-transferase expression in lymphocytes from chronic lymphocytic leukemia patients. Cancer Res. 1990 Jun 15; 50(12):3562-8.
Score: 0.003
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Cellular resistance to a nitric oxide releasing glutathione S-transferase P-activated prodrug, PABA/NO. Invest New Drugs. 2011 Oct; 29(5):719-29.
Score: 0.003
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Glutathione-S-transferase pi as a determinant of drug resistance in transfectant cell lines. J Biol Chem. 1990 Mar 15; 265(8):4296-301.
Score: 0.003
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Cytotoxicity and DNA damaging effects of a new nitrosourea, fotemustine, diethyl- 1-(3-(2-chloroethyl)-3-nitrosoureido) ethylphosphonate-S10036. Anticancer Res. 1989 Nov-Dec; 9(6):1617-22.
Score: 0.003
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Intracellular effects of estramustine (Estracyt/Emcyt). Prog Clin Biol Res. 1989; 303:169-75.
Score: 0.003
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Estramustine--a nitrogen mustard/steroid with antimicrotubule activity. Pharmacol Ther. 1989; 43(3):299-319.
Score: 0.003
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Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines. Cancer Res. 1988 Jul 01; 48(13):3622-5.
Score: 0.003
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Glutathione S-transferases in human prostate. Biochim Biophys Acta. 1987 Oct 08; 926(1):8-15.
Score: 0.003
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The ATP-binding cassette transporter ABCA2 as a mediator of intracellular trafficking. Biomed Pharmacother. 2006 Nov; 60(9):587-92.
Score: 0.003
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Relationship of glutathione depletion and inhibition of glutathione-S-transferase activity to the antimitotic properties of estramustine. Cancer Treat Rep. 1986 Jun; 70(6):715-20.
Score: 0.003
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PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity. J Med Chem. 2006 Feb 09; 49(3):1157-64.
Score: 0.002
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Dansylated estramustine, a fluorescent probe for studies of estramustine uptake and identification of intracellular targets. Proc Natl Acad Sci U S A. 1985 Dec; 82(24):8483-7.
Score: 0.002
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Antimicrotubule effects of estramustine, an antiprostatic tumor drug. Cancer Res. 1985 Aug; 45(8):3891-7.
Score: 0.002
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Biochemical and cytotoxic properties of the isomeric forms of N,N'-bis[N-2-chloroethyl)-N-nitrosocarbamoyl] cystamine. Biochem Pharmacol. 1984 Aug 15; 33(16):2575-80.
Score: 0.002
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Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation. Br J Cancer. 2004 Jun 14; 90(12):2411-7.
Score: 0.002
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Cytotoxic properties of estramustine unrelated to alkylating and steroid constituents. Urology. 1984 Jun; 23(6 Suppl):28-33.
Score: 0.002
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Sulfur containing amino acids and human disease. Biomed Pharmacother. 2004 Jan; 58(1):47-55.
Score: 0.002
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Alkylating agent interactions with the nuclear matrix. Biochem Pharmacol. 1983 Dec 01; 32(23):3509-16.
Score: 0.002
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The mechanism of action of estramustine. Semin Oncol. 1983 Sep; 10(3 Suppl 3):21-6.
Score: 0.002
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Cytotoxicity of estramustine, a steroid-nitrogen mustard derivative, through non-DNA targets. Mol Pharmacol. 1983 Sep; 24(2):324-8.
Score: 0.002
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Molecular modes of action of artesunate in tumor cell lines. Mol Pharmacol. 2003 Aug; 64(2):382-94.
Score: 0.002
-
The importance of glutathione in human disease. Biomed Pharmacother. 2003 May-Jun; 57(3-4):145-55.
Score: 0.002
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Polyphenols: do they play a role in the prevention of human pathologies? Biomed Pharmacother. 2002 Jun; 56(4):200-7.
Score: 0.002
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Enhancement of nitrosourea cytotoxicity in vitro using hydrocortisone. Biochem Pharmacol. 1982 Mar 15; 31(6):1179-80.
Score: 0.002
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Influence of hydrocortisone on the binding of nitrosoureas to nuclear chromatin subfractions. Cancer Res. 1980 Oct; 40(10):3697-3703.
Score: 0.002
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Double high-dose chemotherapy with stem cell rescue (HD-SCR) in patients with breast cancer - effect of sequence. Cancer Chemother Pharmacol. 2000; 45(3):239-46.
Score: 0.002
-
Role of redox potential and reactive oxygen species in stress signaling. Oncogene. 1999 Nov 01; 18(45):6104-11.
Score: 0.002
-
Oxidative stress induced in pathologies: the role of antioxidants. Biomed Pharmacother. 1999 May; 53(4):169-80.
Score: 0.002
-
Estramustine resistance correlates with tau over-expression in human prostatic carcinoma cells. Int J Cancer. 1998 Aug 12; 77(4):626-31.
Score: 0.001
-
Tumor efficacy and bone marrow-sparing properties of TER286, a cytotoxin activated by glutathione S-transferase. Cancer Res. 1998 Jun 15; 58(12):2568-75.
Score: 0.001
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Association of estramustine resistance in human prostatic carcinoma cells with modified patterns of tubulin expression. Biochem Pharmacol. 1998 Feb 01; 55(3):325-31.
Score: 0.001
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Increase of beta(III)- and beta(IVa)-tubulin isotopes in human prostate carcinoma cells as a result of estramustine resistance. Cancer Res. 1996 Jun 01; 56(11):2584-9.
Score: 0.001
-
Cellular and in vitro transport of glutathione conjugates by MRP. Biochemistry. 1996 May 07; 35(18):5719-25.
Score: 0.001
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Isozyme-specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines. Cancer Chemother Pharmacol. 1996; 37(4):363-70.
Score: 0.001
-
Glutathione and drug resistance. Cancer Invest. 1996; 14(2):158-68.
Score: 0.001
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Modulation of glutathione and related enzymes in reversal of resistance to anticancer drugs. Hematol Oncol Clin North Am. 1995 Apr; 9(2):383-96.
Score: 0.001
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Pharmakokinetics and bioavailability study of ethacrynic acid as a modulator of drug resistance in patients with cancer. J Pharmacol Exp Ther. 1994 Sep; 270(3):1186-91.
Score: 0.001
-
Phase II study of estramustine and vinblastine, two microtubule inhibitors, in hormone-refractory prostate cancer. J Clin Oncol. 1992 Nov; 10(11):1754-61.
Score: 0.001
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Depletion of glutathione in normal and malignant human cells in vivo by buthionine sulfoximine: clinical and biochemical results. J Natl Cancer Inst. 1992 Feb 19; 84(4):264-7.
Score: 0.001
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Phase I study of thiotepa in combination with the glutathione transferase inhibitor ethacrynic acid. Cancer Res. 1991 Nov 15; 51(22):6059-65.
Score: 0.001
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Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid. Biochem Pharmacol. 1991 Sep 12; 42(7):1504-7.
Score: 0.001
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Interaction of forskolin with the P-glycoprotein multidrug transporter. Biochemistry. 1991 Aug 27; 30(34):8371-9.
Score: 0.001
-
Determinants of drug response in a cisplatin-resistant human lung cancer cell line. Jpn J Cancer Res. 1990 May; 81(5):527-35.
Score: 0.001
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Estramustine binds a MAP-1-like protein to inhibit microtubule assembly in vitro and disrupt microtubule organization in DU 145 cells. J Cell Biol. 1988 Dec; 107(6 Pt 2):2647-56.
Score: 0.001
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Immunofluorescent studies of the anti-microtubule effects of the anti-cancer drug estramustine. Anticancer Res. 1987 Nov-Dec; 7(6):1165-71.
Score: 0.001
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Mechanism of action of 2-haloethylnitrosoureas on deoxyribonucleic acid. Pathways of aqueous decomposition and pharmacological characteristics of new anticancer disulfide-linked nitrosoureas. Biochem Pharmacol. 1985 Apr 01; 34(7):1015-24.
Score: 0.001
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Effect of 1-methyl-1-nitrosourea on poly(adenosine diphosphate-ribose) polymerase activity at the nucleosomal level. Cancer Res. 1979 Apr; 39(4):1405-10.
Score: 0.000
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Nitrosourea interaction with chromatin and effect on poly(adenosine diphosphate ribose) polymerase activity. Cancer Res. 1979 Apr; 39(4):1411-7.
Score: 0.000