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This is a "connection" page, showing publications co-authored by Kenneth Tew and Danyelle Townsend.
Kenneth Tew
Connection Strength
9.834
Danyelle Townsend
  1. Glutathione-s-transferases as determinants of cell survival and death. Antioxid Redox Signal. 2012 Dec 15; 17(12):1728-37.
    View in: PubMed
    Score: 0.439
  2. The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer. Free Radic Biol Med. 2011 Jul 15; 51(2):299-313.
    View in: PubMed
    Score: 0.406
  3. Regulatory functions of glutathione S-transferase P1-1 unrelated to detoxification. Drug Metab Rev. 2011 May; 43(2):179-93.
    View in: PubMed
    Score: 0.402
  4. Redox platforms in cancer drug discovery and development. Curr Opin Chem Biol. 2011 Feb; 15(1):156-61.
    View in: PubMed
    Score: 0.394
  5. Nitrosative stress-induced s-glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein response. Cancer Res. 2009 Oct 01; 69(19):7626-34.
    View in: PubMed
    Score: 0.364
  6. Novel role for glutathione S-transferase pi. Regulator of protein S-Glutathionylation following oxidative and nitrosative stress. J Biol Chem. 2009 Jan 02; 284(1):436-445.
    View in: PubMed
    Score: 0.342
  7. Pharmacology of a mimetic of glutathione disulfide, NOV-002. Biomed Pharmacother. 2009 Feb; 63(2):75-8.
    View in: PubMed
    Score: 0.339
  8. NOV-002, a mimetic of glutathione disulfide. Expert Opin Investig Drugs. 2008 Jul; 17(7):1075-83.
    View in: PubMed
    Score: 0.334
  9. NOV-002, a glutathione disulfide mimetic, as a modulator of cellular redox balance. Cancer Res. 2008 Apr 15; 68(8):2870-7.
    View in: PubMed
    Score: 0.329
  10. A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins. Mol Pharmacol. 2006 Feb; 69(2):501-8.
    View in: PubMed
    Score: 0.279
  11. Glutathione S-transferases as regulators of kinase pathways and anticancer drug targets. Methods Enzymol. 2005; 401:287-307.
    View in: PubMed
    Score: 0.262
  12. Glutathione and ABC transporters as determinants of sensitivity to oxidative and nitrosative stress. J Nutr. 2004 Nov; 134(11):3205S-3206S.
    View in: PubMed
    Score: 0.259
  13. The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene. 2003 Oct 20; 22(47):7369-75.
    View in: PubMed
    Score: 0.241
  14. Cancer drugs, genetic variation and the glutathione-S-transferase gene family. Am J Pharmacogenomics. 2003; 3(3):157-72.
    View in: PubMed
    Score: 0.228
  15. Efficacy of a glutathione S-transferase pi-activated prodrug in platinum-resistant ovarian cancer cells. Mol Cancer Ther. 2002 Oct; 1(12):1089-95.
    View in: PubMed
    Score: 0.224
  16. Cisplatin chemotherapy and renal function. Adv Cancer Res. 2021; 152:305-327.
    View in: PubMed
    Score: 0.203
  17. Glutathione S-Transferase P Influences Redox Homeostasis and Response to Drugs that Induce the Unfolded Protein Response in Zebrafish. J Pharmacol Exp Ther. 2021 04; 377(1):121-132.
    View in: PubMed
    Score: 0.200
  18. Development of Telintra as an Inhibitor of Glutathione S-Transferase P. Handb Exp Pharmacol. 2021; 264:71-91.
    View in: PubMed
    Score: 0.199
  19. Altered redox regulation and S-glutathionylation of BiP contribute to bortezomib resistance in multiple myeloma. Free Radic Biol Med. 2020 11 20; 160:755-767.
    View in: PubMed
    Score: 0.195
  20. Voltage-Dependent Anion Channels Influence Cytotoxicity of ME-344, a Therapeutic Isoflavone. J Pharmacol Exp Ther. 2020 08; 374(2):308-318.
    View in: PubMed
    Score: 0.191
  21. S-Glutathionylated Serine Proteinase Inhibitors as Biomarkers for Radiation Exposure in Prostate Cancer Patients. Sci Rep. 2019 09 24; 9(1):13792.
    View in: PubMed
    Score: 0.182
  22. Isoflavone ME-344 Disrupts Redox Homeostasis and Mitochondrial Function by Targeting Heme Oxygenase 1. Cancer Res. 2019 08 15; 79(16):4072-4085.
    View in: PubMed
    Score: 0.179
  23. Racial disparities, cancer and response to oxidative stress. Adv Cancer Res. 2019; 144:343-383.
    View in: PubMed
    Score: 0.177
  24. Pharmacology of ME-344, a novel cytotoxic isoflavone. Adv Cancer Res. 2019; 142:187-207.
    View in: PubMed
    Score: 0.175
  25. An evolving understanding of the S-glutathionylation cycle in pathways of redox regulation. Free Radic Biol Med. 2018 05 20; 120:204-216.
    View in: PubMed
    Score: 0.164
  26. S-Glutathionylation of estrogen receptor a affects dendritic cell function. J Biol Chem. 2018 03 23; 293(12):4366-4380.
    View in: PubMed
    Score: 0.162
  27. Redox Signaling and Bioenergetics Influence Lung Cancer Cell Line Sensitivity to the Isoflavone ME-344. J Pharmacol Exp Ther. 2016 08; 358(2):199-208.
    View in: PubMed
    Score: 0.145
  28. Glutathione S-Transferase P-Mediated Protein S-Glutathionylation of Resident Endoplasmic Reticulum Proteins Influences Sensitivity to Drug-Induced Unfolded Protein Response. Antioxid Redox Signal. 2017 02 20; 26(6):247-261.
    View in: PubMed
    Score: 0.143
  29. Oxidative stress, redox regulation and diseases of cellular differentiation. Biochim Biophys Acta. 2015 Aug; 1850(8):1607-21.
    View in: PubMed
    Score: 0.130
  30. Glutathione S-transferase P influences redox and migration pathways in bone marrow. PLoS One. 2014; 9(9):e107478.
    View in: PubMed
    Score: 0.128
  31. S-glutathionylation of buccal cell proteins as biomarkers of exposure to hydrogen peroxide. BBA Clin. 2014 Dec; 2:31-9.
    View in: PubMed
    Score: 0.128
  32. Pleiotropic functions of glutathione S-transferase P. Adv Cancer Res. 2014; 122:143-75.
    View in: PubMed
    Score: 0.122
  33. Causes and consequences of cysteine S-glutathionylation. J Biol Chem. 2013 Sep 13; 288(37):26497-504.
    View in: PubMed
    Score: 0.118
  34. Sulfiredoxin redox-sensitive interaction with S100A4 and non-muscle myosin IIA regulates cancer cell motility. Biochemistry. 2012 Oct 02; 51(39):7740-54.
    View in: PubMed
    Score: 0.112
  35. Ablation of the ATP-binding cassette transporter, Abca2 modifies response to estrogen-based therapies. Biomed Pharmacother. 2012 Sep; 66(6):403-8.
    View in: PubMed
    Score: 0.110
  36. S-Glutathionylation of Protein Disulfide Isomerase Regulates Estrogen Receptor a Stability and Function. Int J Cell Biol. 2012; 2012:273549.
    View in: PubMed
    Score: 0.109
  37. S-glutathionylated serine proteinase inhibitors as plasma biomarkers in assessing response to redox-modulating drugs. Cancer Res. 2012 May 01; 72(9):2383-93.
    View in: PubMed
    Score: 0.108
  38. S-glutathionylation: from molecular mechanisms to health outcomes. Antioxid Redox Signal. 2011 Jul 01; 15(1):233-70.
    View in: PubMed
    Score: 0.102
  39. Diazeniumdiolate mediated nitrosative stress alters nitric oxide homeostasis through intracellular calcium and S-glutathionylation of nitric oxide synthetase. PLoS One. 2010 Nov 30; 5(11):e14151.
    View in: PubMed
    Score: 0.099
  40. ABCA2 transporter deficiency reduces incidence of TRAMP prostate tumor metastasis and cellular chemotactic migration. Cancer Lett. 2011 Jan 28; 300(2):154-61.
    View in: PubMed
    Score: 0.098
  41. The impact of redox and thiol status on the bone marrow: Pharmacological intervention strategies. Pharmacol Ther. 2011 Feb; 129(2):172-84.
    View in: PubMed
    Score: 0.098
  42. Cellular resistance to a nitric oxide releasing glutathione S-transferase P-activated prodrug, PABA/NO. Invest New Drugs. 2011 Oct; 29(5):719-29.
    View in: PubMed
    Score: 0.094
  43. Protective effects of a glutathione disulfide mimetic (NOV-002) against cisplatin induced kidney toxicity. Biomed Pharmacother. 2010 Jan; 64(1):73-6.
    View in: PubMed
    Score: 0.091
  44. Role of glutathione S-transferase Pi in cisplatin-induced nephrotoxicity. Biomed Pharmacother. 2009 Feb; 63(2):79-85.
    View in: PubMed
    Score: 0.085
  45. The ABCA2 transporter: intracellular roles in trafficking and metabolism of LDL-derived cholesterol and sterol-related compounds. Curr Drug Metab. 2007 Jan; 8(1):47-57.
    View in: PubMed
    Score: 0.075
  46. "Skittish" Abca2 knockout mice display tremor, hyperactivity, and abnormal myelin ultrastructure in the central nervous system. Mol Cell Biol. 2007 Jan; 27(1):44-53.
    View in: PubMed
    Score: 0.074
  47. A novel role for human sulfiredoxin in the reversal of glutathionylation. Cancer Res. 2006 Jul 01; 66(13):6800-6.
    View in: PubMed
    Score: 0.073
  48. Evaluation of lipophilins as determinants of tumor cell response to estramustine. J Pharmacol Exp Ther. 2005 Dec; 315(3):1158-62.
    View in: PubMed
    Score: 0.069
  49. Characterization of the ATPase activity of human ATP-binding cassette transporter-2 (ABCA2). In Vivo. 2005 Jul-Aug; 19(4):657-60.
    View in: PubMed
    Score: 0.068
  50. Tumor cell responses to a novel glutathione S-transferase-activated nitric oxide-releasing prodrug. Mol Pharmacol. 2004 May; 65(5):1070-9.
    View in: PubMed
    Score: 0.063
  51. Organosulfur compounds from alliaceae in the prevention of human pathologies. Biomed Pharmacother. 2004 Apr; 58(3):183-93.
    View in: PubMed
    Score: 0.062
  52. Sulfur containing amino acids and human disease. Biomed Pharmacother. 2004 Jan; 58(1):47-55.
    View in: PubMed
    Score: 0.061
  53. The importance of glutathione in human disease. Biomed Pharmacother. 2003 May-Jun; 57(3-4):145-55.
    View in: PubMed
    Score: 0.058
  54. Oxidative stress induces senescence in breast cancer stem cells. Biochem Biophys Res Commun. 2019 07 05; 514(4):1204-1209.
    View in: PubMed
    Score: 0.044
  55. A seleno-hormetine protects bone marrow hematopoietic cells against ionizing radiation-induced toxicities. PLoS One. 2019; 14(4):e0205626.
    View in: PubMed
    Score: 0.044
  56. MGST1, a GSH transferase/peroxidase essential for development and hematopoietic stem cell differentiation. Redox Biol. 2018 07; 17:171-179.
    View in: PubMed
    Score: 0.041
  57. Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase p. JCI Insight. 2016 Jun 02; 1(8).
    View in: PubMed
    Score: 0.036
  58. Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells. Mol Pharm. 2016 06 06; 13(6):2010-25.
    View in: PubMed
    Score: 0.036
  59. Glutathione S-transferase pi modulates NF-?B activation and pro-inflammatory responses in lung epithelial cells. Redox Biol. 2016 08; 8:375-82.
    View in: PubMed
    Score: 0.036
  60. Adverse Outcomes Associated with Cigarette Smoke Radicals Related to Damage to Protein-disulfide Isomerase. J Biol Chem. 2016 Feb 26; 291(9):4763-78.
    View in: PubMed
    Score: 0.035
  61. Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-? production by altering Nicastrin maturation and intracellular localization. J Biol Chem. 2012 Jan 06; 287(2):1100-11.
    View in: PubMed
    Score: 0.026
  62. Cocaine-induced adaptations in cellular redox balance contributes to enduring behavioral plasticity. Neuropsychopharmacology. 2011 Nov; 36(12):2551-60.
    View in: PubMed
    Score: 0.026
  63. PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity. J Med Chem. 2006 Feb 09; 49(3):1157-64.
    View in: PubMed
    Score: 0.018
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